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The second edition of Transfusion Medicine and Hemostasis continues to be the only "pocket-size" quick reference for pathology residents and transfusion medicine fellows. It covers all topics in blood banking, transfusion medicine, and clinical and laboratory based coagulation. Short, focused chapters, organized by multiple hierarchical headings, are supplemented with up to 10 suggested reading citations. This single reference covers essentially all the topics required to meet the goals and objectives of a major program in transfusion medicine and clinical coagulation. New chapters in the coagulation testing section reflect the development of new tests available and their incorporation into clinical practice. Coverage includes essential updates on the importance of new cellular therapies, peripheral blood and bone marrow hematopoietic progenitor cells, as well as cord blood banking and regenerative medicine. The authors also examine advances in the understanding of molecular testing and pathogen reduction in two separate quality control chapters (one for blood centers and one for hospitals). Updated content covers new coagulation tests, cellular therapies, and quality control issuesEasy to use, with focused, well-defined chapters in a standardized format throughoutOffers quick "cross-reference" lists at the end of each chapter Includes lists of common abbreviations and indexes that cross reference diagnostic, clinical and therapeutic commonalities.
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All patients arriving at hospital with chest pain suggestive of myocardial ischemia require an immediate 12-lead ECG and medical assessment. Management will depend on the type of acute coronary syndrome (ACS) diagnosed. 'Fast Facts: Acute Coronary Syndromes' is an international evidence-based primer that focuses on optimizing patient outcomes via accurate initial diagnosis, appropriate risk stratification and proper therapeutic decision-making in line with both American and European management guidelines. This refreshingly readable handbook simplifies the complexities involved in the care of patients with ACS by: • Familiarizing readers with the common pathophysiology underlying all ACS • Detailing the specifics of clinical assessment (targeted history, symptom-oriented physical exam, electrocardiography, cardiac biomarkers and imaging) • Assisting best practice in ischemic risk stratification and assessment of bleeding risk • Outlining coronary revascularization techniques, reperfusion strategies and preventive measures • Providing an update on potent antithrombotic therapy (antiplatelet agents and anticoagulants) • Clearly explaining the latest developments that are likely to be implemented in the near future. In this fast-changing field it is difficult for healthcare professionals to remain current and virtually impossible to fully understand all of the subtle nuances of the available clinical trial data. This comprehensive handbook is therefore the essential resource for all healthcare professionals looking for up-to-date, easy-to read information that will assist best practice in the identification and management of all patients with ACS. Contents: • Pathophysiology • Diagnosis • Risk stratification and decision-making • Coronary revascularization • Unstable angina/non-ST-segment elevation myocardial infarction • ST-segment elevation myocardial infarction • Secondary prevention of coronary artery disease • Developments • Useful resources
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Our understanding of the mechanisms and management of cardiac arrhythmias has improved dramatically in recent years thanks to continuing basic research coupled with technological advances. 'Fast Facts: Cardiac Arrhythmias' translates this improved understanding into straightforward guidance for managing patients presenting with signs of cardiac arrhythmia. The third edition of this highly readable handbook has been thoroughly updated to include recent pharmacological advances, such as the gradual replacement of warfarin anticoagulation with the novel direct oral anticoagulants. Also discussed are technological advances, including the use of smartphone and smartwatch systems to record heart rhythms, and the latest thinking on catheter and surgical ablation. New chapters have been added on the management of syncope and sudden cardiac death. These complement well-illustrated chapters describing normal conduction within the heart, the underlying mechanisms of arrhythmias and general investigation and management principles, as well as chapters discussing the definition, causes, diagnosis and management of specific arrhythmias. Other highlights include chapters on the rare, but increasingly recognized, inherited arrhythmias, as well as on the use of pacemakers and implantable cardioverter defibrillators. Of interest to primary care practitioners, nurses, medical students, technicians and cardiologists in training, this practical review of the mechanisms of heart rhythm abnormality and the contemporary therapies available provides a useful resource for improving patient care. Contents: • Normal conduction and mechanisms of arrhythmias • Presentation • Syncope • Sudden cardiac death • Investigation • Management principles • Supraventricular arrhythmias • Atrial flutter and atypical atrial flutter • Atrial fibrillation • Ventricular arrhythmias • Rare and inherited arrhythmias • Cardiac devices: pacemakers and defibrillators
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Recent progress in interventional therapies has revolutionized the management of cardiac arrhythmias, resulting in a remarkable improvement in outcomes for patients. Yet the diagnosis and management of arrhythmias are still viewed as a complex and inaccessible area of modern cardiology. 'Fast Facts: Cardiac Arrhythmias' cuts through the technical detail to provide a better understanding of how the patient with arrhythmia presents, and how the problem should be best investigated and managed. Highlights include: • Succinct descriptions with clear well-annotated illustrations of normal conduction and the mechanisms of arrhythmias • A simple classification of arrhythmias based on 12-lead ECG patterns • A comprehensive review of presenting signs and symptoms, with key questions to ask the patient • A logical approach to investigation: predict it (history and examination), wait for it (monitoring) or provoke it (electrophysiological testing) • Practical information on management options: pharmacological therapy, direct cardioversion, catheter ablation and cardiac devices • The latest international guidelines on atrial fibrillation and catheter and surgical ablation • Important pharmacological updates, including the latest thinking on anticoagulation. This highly readable handbook is a practical resource for all primary care physicians, cardiologists in training, cardiac nurses, technicians and medical students seeking a better understanding of the mechanisms of arrhythmias and the contemporary therapies available, with a view to improving patient care. Contents: • Conduction within the heart • Classification and mechanisms of arrhythmias • Presenting signs and symptoms • Investigation • Management principles • Supraventricular arrhythmias • Atrial flutter • Atrial fibrillation • Ventricular arrhythmias • Rare and unusual arrhythmias • Cardiac devices: Pacemakers and defibrillators • Useful resources
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A better understanding of the mechanisms and pathophysiological pathways of heart failure (HF), improved management of associated comorbidities, and advances in identifying genetic cardiac disease have led to a near-revolution in the management of patients in terms of pharmacological treatments, surgery and devices. These developments have transformed outcomes and HF-associated mortality, and gene therapies further promise a brighter future for patients who experience the debilitating effects of HF.This new edition of 'Fast Facts: Heart Failure' starts with the definitions of HF (different types of HF require different treatments), then provides the latest thinking on mechanisms and clinical stages, underlying causes and the assessment and management of comorbidities. This is followed by simple diagnostic criteria and a comprehensive overview of investigations. The management chapters focus on the importance of self-care education and healthy lifestyle choices, together with the latest recommendations for pharmacological treatment, device therapy and cardiac surgery from international guidelines. The final chapter on developments is an indication of the ongoing innovation in this rapidly moving field.Table of Contents:• Definitions, classification and epidemiology• Pathophysiology and clinical stages• Causes• Comorbidities• Diagnosis• General management and lifestyle considerations• Pharmacological treatment• Non-pharmacological management• Advanced HF therapies• Prognosis• Developments and future directions
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Effective new treatments - from drugs to surgery to devices - are revolutionizing both outcome and wellbeing in patients with heart failure. Written with the non-specialist in mind, this practical resource distills a lot of complex information into a refreshingly readable format, with clear informative diagrams and useful pull-out tables. Highlights include: • a concise discussion of the pathophysiological mechanisms that lead to heart failure • a detailed review of the causes and comorbidities of heart failure • simple advice on diagnosis and investigation • clear management principles, including healthy lifestyle choices for patients • evidence-based guidance on first- and second-line drug therapies and medical management that targets the underlying cause • a comprehensive overview of non-pharmacological treatment options, including devices and transplantation • important information on palliative care in end-stage heart failure. 'Fast Facts: Heart Failure' is the ideal resource for primary care providers, specialist nurses and cardiology trainees, and a good introduction to heart failure for all healthcare professionals who care for the elderly. Contents: • Definitions and epidemiology • Pathophysiology and clinical stages • Causes • Comorbidities • Diagnosis • General management and lifestyle considerations • Pharmacological treatment • Non-pharmacological treatment • Prognosis • Clinical trials and developments • Useful resources
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'Fast Facts: Hyperlipidemia' provides a crisp and accurate summary of lipid disorders using clear language and illustrations. Directed at a broad range of healthcare professionals, from primary care physicians to specialists, this updated fifth edition addresses the importance of considering lipoprotein particles, not just their lipids. The authors, renowned experts from the UK and USA, interpret clinical trial evidence in the context of pathogenesis and provide practical solutions to the routine problems encountered in the clinical management of hyperlipidemias. Contents: • Lipids and lipoproteins - structure and physiology • Epidemiology and pathophysiology • Familial (monogenic) hypercholesterolemia • Polygenic hypercholesterolemia and combined hyperlipidemia • Hypertriglyceridemia • Familial dysbetalipoproteinemia • Dyslipidemia in insulin resistance, the metabolic syndrome and diabetes mellitus • Secondary hyperlipidemia • Dietary treatment • Drug treatment • When to treat • Biochemical tests • Useful resources
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