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Due to the emergence of organocatalysis as a highly active and very exciting field of research both in academia and the life sciences industry, an Ernst Schering Research Foundation Symposium was organized in 2007 to bring together the scientific leaders in this field and to discuss the basics and current progress of organocatalysis and its application in drug discovery. Various aspects of organocatalysis are addressed in this volume, covering a broad range of synthetic transformations such as functional group interconversions as well as CC- and CX-bond formations and their applications in natural product and drug syntheses. In addition, the design and scope of various catalyst systems are discussed, from small molecules, to peptides, to genetically engineered enzymes.

Asymmetric synthesis --- Catalysis --- Asymmetric induction --- Induction, Asymmetric --- Synthesis, Asymmetric --- Asymmetry (Chemistry) --- Organic compounds --- Synthesis

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The world is chiral. Most of the molecules in it are chiral, and asymmetric synthesis is an important means by which enantiopure chiral molecules may be obtained for study and sale. Using examples from the literature of asymmetric synthesis, this book presents a detailed analysis of the factors that govern stereoselectivity in organic reactions. After an explanation of the basic physical-organic principles governing stereoselective reactions, the authors provide a detailed, annotated glossary of stereochemical terms. A chapter on ""Practical Aspects of Asymmetric Synthesis"" provide

Asymmetric synthesis. --- Asymmetric synthesis --- Chemistry --- Physical Sciences & Mathematics --- Organic Chemistry --- Asymmetric induction --- Induction, Asymmetric --- Synthesis, Asymmetric --- Asymmetry (Chemistry) --- Organic compounds --- Synthesis

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Les applications des auxiliaires, des réactifs et des catalyseurs chiraux en synthèse asymétrique. L'ouvrage expose les principales réactions de la synthèse asymétrique et offre une approche critique des différente méthologies à partir d'exemples récents.

Asymmetric synthesis. --- Catalysis. --- Chirality. --- Ligands (Biochemistry) --- Biochemistry --- Stereochemistry --- Symmetry (Physics) --- Enantiomers --- Activation (Chemistry) --- Chemistry, Physical and theoretical --- Surface chemistry --- Asymmetric induction --- Induction, Asymmetric --- Synthesis, Asymmetric --- Asymmetry (Chemistry) --- Organic compounds --- Synthesis

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Organic compounds --- Iridium catalysts. --- Asymmetric synthesis. --- Synthesis. --- Asymmetric induction --- Induction, Asymmetric --- Synthesis, Asymmetric --- Asymmetry (Chemistry) --- Catalysts, Iridium --- Platinum group catalysts --- Chemistry, Organic --- Chemistry, Synthetic organic --- Organic synthesis (Chemistry) --- Synthetic organic chemistry --- Synthesis

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Qi-Lin Zhou and Jian-Hua Xie: Chiral Spiro Catalysts.- Fuk Loi Lam, Fuk Yee Kwong and Albert S. C. Chan: Chiral Phosphorus Ligands with Interesting Properties and Practical Applications.- Jiang Pan, Hui-Lei Yu, Jian-He Xu, Guo-Qiang Lin: Advances in Biocatalysis: Enzymatic Reactions and Their Applications.- Mei-Xiang Wang: Enantioselective Biotransformations of Nitriles.- Man Kin Wong, Yiu Chung Yip and Dan Yang: Asymmetric Epoxidation Catalyzed by Chiral Ketones.- W. J. Liu, N. Li and L. Z. Gong: Asymmetric Organocatalysis.- Qing-Hua Fan and Kuiling Ding: Enantioselective Catalysis with Structurally Tunable Immobilized Catalysts.- Chang-Hua Ding, Xue-Long Hou: Transition Metal-Catalyzed Asymmetric Allylation.- Jian Zhou and Yong Tang: Enantioselective Reactions with Trisoxazolines.- Xiang-Ping Hu, Duo-Sheng Wang, Chang-Bin Yu, Yong-Gui Zhou, and Zhuo Zheng: Adventure in Asymmetric Hydrogenation: Synthesis of Chiral Phosphorus Ligands and Asymmetric Hydrogenation of Heteroaromtics.

Catalysis --- Asymmetric synthesis --- Chemistry --- Physical Sciences & Mathematics --- Physical & Theoretical Chemistry --- Organic Chemistry --- Catalysis. --- Asymmetric synthesis. --- Asymmetric induction --- Induction, Asymmetric --- Synthesis, Asymmetric --- Chemistry. --- Organic chemistry. --- Organometallic chemistry. --- Organometallic Chemistry. --- Organic Chemistry. --- Activation (Chemistry) --- Chemistry, Physical and theoretical --- Surface chemistry --- Asymmetry (Chemistry) --- Organic compounds --- Synthesis --- Chemistry, Organic. --- Organic chemistry --- Organometallic chemistry . --- Chemistry, Organometallic --- Metallo-organic chemistry --- Chemistry, Organic