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Blood group antigens --- Antigens --- Blood Group Antigens --- Antigen --- Erythrocytes --- Isoantigens --- immunology --- ANTIGENS --- BLOOD GROUPS --- HANDBOOKS --- IMMUNOLOGY

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The HLA FactsBook presents up-to-date and comprehensive information on the HLA genes in a manner that is accessible to both beginner and expert alike. The focus of the book is on the polymorphic HLA genes (HLA-A, B, C, DP, DQ, and DR) that are typed for in clinical HLA laboratories. Each gene has a dedicated section in which individual entries describe the structure, functions, and population distribution of groups of related allotypes. Fourteen introductory chapters provide a beginner's guide to the basic structure, function, and genetics of the HLA genes, as well as to the nomenclatur

HLA histocompatibility antigens --- Histocompatibility antigens. --- Isoantigens --- HL-A histocompatibility antigens --- HLA antigens --- HLA transplantation antigens --- Human leukocyte antigens --- Transplantation antigens, Human --- Histocompatibility antigens --- Major histocompatibility complex

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GENETICS, POPULATION --- ANTIBODIES, MONOCLONAL --- BLOOD CHEMICAL ANALYSIS --- DNA --- ELECTROPHORESIS --- ISOANTIGENS --- STAINS AND STAINING --- CONGRESSES --- DIAGNOSTIC USE --- STATISTICS AND NUMERICAL DATA --- METABOLISM --- Genetics, Population

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This third volume of "Uveitis and Immunological Disorders" in Essentials in Ophthalmology provides up-to-date, relevant information for the reader. Our knowledge and understanding of immune mechanisms has increased exponentially over the past few years and has expanded to disorders such as diabetic retinopathy and macular degeneration. This volume will provide the ophthalmologist with practical information on how to diagnose and treat these difficult, and in some cases, blinding disorders. In addition, there are important discussions of the mechanisms underlying these conditions, which incorporate the most recent, up-to-date research material available. "Summary for the Clinician" and "Core Messages" sections enhance the value of each chapter. This volume was written by authors who are leaders in their field. Important and provocative questions dealing with recent developments are raised. Topics covered include: To do or not to do? HLA typing in keratoplasty Acute anterior uveitis and HLA-B27: what is new? Keratouveitis: new aspects on diagnosis and management Steroid sensitivity in uveitis Is Behcet’s retinal vasculitis different from idiopathic retinal vasculitis? Is the diagnosis important in sight-threatening non-infectious uveitis? Uveitis and multiple sclerosis: is there a real link? Inflammation and AMD: what is the evidence? Diabetic retinopathy: an inflammatory disorder? Pathophysiology and its consequences. This highly practical and clinically relevant volume is valuable to all those involved in the handling and treatment of patients with ocular inflammation. In addition, it provides fresh perspectives and insights into our current understanding of common disorders such as diabetic retinopathy and macular degeneration.

Eye -- Diseases -- Immunological aspects. --- Eye -- Immunology. --- Eye Diseases -- immunology. --- Eye Diseases -- physiopathology. --- Eye Diseases -- therapy. --- Uveitis -- immunology. --- Uveitis. --- HLA-B27 Antigen --- Eye Diseases --- Uveitis --- HLA-B Antigens --- Uveal Diseases --- Diseases --- HLA Antigens --- Histocompatibility Antigens Class I --- Histocompatibility Antigens --- Antigens, Surface --- Isoantigens --- Antigens --- Biological Factors --- Chemicals and Drugs --- Ophthalmology & Optometry --- Medicine --- Health & Biological Sciences --- Eye --- Immunological aspects. --- Eyeball --- Eyes --- Visual system --- Uvea --- Inflammation --- Medicine. --- Ophthalmology. --- Medicine & Public Health. --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Medical sciences --- Pathology --- Physicians --- Face --- Photoreceptors --- Vision

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We have entered the era of molecular immunohematology in which DNA is analyzed to predict red blood cell and platelet phenotypes. Indeed, many laboratories and blood banks across the world have already adopted and implemented molecular techniques. Some fear that serology is now becoming outdated, but immunohematology techniques often supplement the work of serologists, and several leading serology laboratories are the very same ones that were early adopters of molecular immunohematology. This book is a thorough review of molecular immunohematology and is aimed at anyone interested in how it is changing blood bank and transfusion medicine. BeadChip Molecular Immunohematology opens with a history of serology before it provides an overview of gene expression, how genetic variations translate into antigenic differences on the surfaces of cells, and techniques that have been developed to detect genetic variations. It then describes in detail the BeadChip technology developed by BioArray Solutions, the molecular immunohematology system that has been most widely adopted in blood blank laboratories. The remainder of the book focuses on analyses and case studies from around the world to describe how molecular immunohematology is being used in various settings for various purposes. It includes a discussion of the significant advances that have been made to incorporate Rh testing on the BeadChip platform as well as the potential use of that system.

Blood banks -- Congresses. --- Blood banks. --- Blood Group Antigens. --- Blood Grouping and Crossmatching. --- Blood Transfusion -- methods. --- Gene Expression Profiling. --- Hematologic Diseases -- immunology. --- Immunohematology. --- Blood --- Immunology --- Medical laboratories --- Medicine --- Monoclonal antibodies --- Nucleic Acid Hybridization --- Molecular Probe Techniques --- Genetic Techniques --- Isoantigens --- Investigative Techniques --- Microarray Analysis --- Sequence Analysis --- Biological Specimen Banks --- Antigens, Surface --- Histocompatibility Testing --- Hematologic Tests --- Immunologic Tests --- Antigens --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Microchip Analytical Procedures --- Laboratory Techniques and Procedures --- Health Facilities --- Blood Grouping and Crossmatching --- Oligonucleotide Array Sequence Analysis --- Methods --- Blood Group Antigens --- Gene Expression Profiling --- Blood Banks --- Biological Factors --- Health Care Facilities, Manpower, and Services --- Immunologic Techniques --- Chemistry Techniques, Analytical --- Diagnosis --- Chemicals and Drugs --- Health Care --- Health & Biological Sciences --- Hematologic Diseases --- Transfusion --- Immunology. --- Medical laboratories. --- Medicine. --- Monoclonal antibodies. --- Antibodies, Monoclonal --- Monoclonal immunoglobulins --- Clinical sciences --- Medical profession --- Immunobiology --- Blood transfusion --- Blood transfusion therapy --- Hemotherapy --- Transfusion medicine --- Transfusion of blood --- Transfusion therapy --- Transfusion therapy, Blood --- Transfusion. --- Antibodies. --- Laboratory medicine. --- Molecular biology. --- Blood transfusion. --- Biomedicine. --- Biomedicine general. --- Laboratory Medicine. --- Molecular Medicine. --- Blood Transfusion Medicine. --- Human biology --- Life sciences --- Medical sciences --- Pathology --- Physicians --- Serology --- Immunoglobulins --- Molecular cloning --- Diagnosis, Laboratory --- Health facilities --- Laboratories --- Surgery --- Blood banks --- Blood groups --- Hospitals --- Transfusion-free surgery --- Transfusion committees --- Biomedicine, general. --- Health Workforce --- Molecular biochemistry --- Molecular biophysics --- Biochemistry --- Biophysics --- Biomolecules --- Systems biology --- Clinical medicine --- Clinical pathology --- Diagnostic laboratory tests --- Laboratory diagnosis --- Laboratory medicine --- Medical laboratory diagnosis --- Antibodies --- Immune globulins --- Immune serum globulin --- Blood proteins --- Globulins --- Plasma cells --- Antibody diversity --- Bacterial immunoglobulin-binding proteins