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ASPARTATE AMINOTRANSFERASE --- ANALYSIS

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Glutamate is the major excitatory neurotransmitter in the brain and dysfunction of glutamate transmission is the likely cause of a variety of diseases including neurodegeneration following cerebral ischemia, Huntington's chorea, amyotrophic lateral sclerosis, epilepsy, spasticity, emesis, chronic pain, and schizophrenia. Excitatory amino acid receptor agonists and antagonists are therefore of major interest as potential drugs for central nervous system disorders. Excitatory Amino Acids is the first book entirely dedicated to the results of human testing of modulators of excitatory amino

Excitatory amino acids. --- Excitatory amino acids --- Methyl aspartate --- Pathophysiology. --- Receptors.

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The NMDA receptor plays a critical role in the development of the central nervous system and in adult neuroplasticity, learning, and memory. Therefore, it is not surprising that this receptor has been widely studied. However, despite the importance of rhythms for the sustenance of life, this aspect of NMDAR function remains poorly studied. Written by one of the world's leading authorities on NMDA receptors, ""Biology of the NMDA Receptor"" brings together virtually all the players in this important field.

Methyl aspartate. --- Receptors, N-Methyl-D-Aspartate. --- Methyl aspartate --- Receptors, Ionotropic Glutamate --- Receptors, Glutamate --- Ligand-Gated Ion Channels --- Receptors, Amino Acid --- Receptors, N-Methyl-D-Aspartate --- Receptors. --- Brain research --- Methyl aspartic acid --- Methylaspartate --- Methylaspartic acid --- N-methyl-D-aspartate --- N-methyl-D-aspartic acid --- NMDA (Chemistry) --- Brain --- Research. --- Aspartic acid --- Excitatory amino acids

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This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact

NMDAR = N-methyl-d-aspartate receptor --- Enzymes - metabolism --- enzyme drug target --- d-serine --- L-serine

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Glutamate is the major excitatory neurotransmitter in the brain and dysfunction of glutamate transmission is the likely cause of a variety of diseases including neurodegeneration following cerebral ischemia, Huntington's chorea, amyotrophic lateral sclerosis, epilepsy, spasticity, emesis, chronic pain, and schizophrenia. Excitatory amino acid receptor agonists and antagonists are therefore of major interest as potential drugs for central nervous system disorders. Excitatory Amino Acids is the first book entirely dedicated to the results of human testing of modulators of excitatory amino

Excitatory amino acids. --- Excitatory amino acids --- Methyl aspartate --- Methyl aspartic acid --- Methylaspartate --- Methylaspartic acid --- N-methyl-D-aspartate --- N-methyl-D-aspartic acid --- NMDA (Chemistry) --- Aspartic acid --- Amino acid neurotransmitters --- Pathophysiology. --- Receptors.