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book (5)


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English (5)


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2022 (1)

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2018 (1)

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Book
Breaking tolerance to pancreatic cancer unresponsiveness to chemotherapy
Author:
ISBN: 0128176628 012817661X Year: 2019 Publisher: London, England : Academic Press,


Book

Book
Resistance to Targeted Therapies in Lymphomas
Authors: ---
ISBN: 3030244245 3030244237 Year: 2019 Publisher: Cham : Springer International Publishing : Imprint: Springer,

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Abstract

This volume will review different classes of "target" drugs that have been developed, approved, or are under investigation in the field of lymphoma therapy. The discussion will not only be on the understanding of the mechanisms of action or clinical response of those agents, but also help the reader to understand the nature of lymphoma biology in patients who relapse or are refractor after exposure to those drugs. Contributors will discuss what is currently known about mechanisms of tumor-related or host-related resistance, and how to overcome this resistance. This understanding is crucial given the dismal outcomes of patients with relapsed or refractory lymphomas. The book provides a unique opportunity to review and reflect on the recent successes and pitfalls of the modern lymphoma therapy era. .


Book
Biological Mechanisms of Minimal Residual Disease and Systemic Cancer
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ISBN: 3319977466 3319977458 Year: 2018 Publisher: Cham : Springer International Publishing : Imprint: Springer,

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This book focuses on the biological mechanisms of minimal residual disease (MRD) and recurrence. It integrates this biology in solid cancers and in hematological malignancies. It reports also on technological advancements for monitoring MRD, derived from mechanistic insights. Chapters in solid and hematological malignancies address stem cell biology, genetics, epigenetics and micro-environmental regulation of dormant MRD. Novel insight into technologies for molecular phenotyping of MRD and monitoring of CTCs, DTCs and cell free RNA and DNA are also addressed extensively. Five chapters explore the above concepts in solid cancers such as prostate, breast, melanoma, head and neck and esophageal. Two chapters also explore the basic mechanisms of vascular biology targeting and epigenetic mechanisms regulating pluripotency programs during dormancy. Similar biology is explored in hematological malignancies such as T-ALL, CML, AML and multiple myeloma in additional four chapters. This book is edited and prefaced by Dr. Julio Aguirre-Ghiso, an expert in dormancy and recurrence. The chapters are written by world-recognized experts Drs. Ravi Bahtia, Samir Parekh, Russel Taichman, Monica Guzman, David Hoon, Denis Schewe, Irmela Jeremias, Cyrus Ghajar, Maria Soledad Sosa and Nicholas Stoecklein. The topic of this book is of particular interest to both basic cancer cell biologists and physician scientists that are working to provide a more integrated view of the biology of MRD and to those interested in working on or learning about this paradigm. The integrated and cross-disciplinary focus of the book from biology to medicine seeks to help bridge gaps to improve cancer care and prevent recurrences.


Book
Cancer, Complexity, Computation
Authors: --- ---
ISBN: 9783031043796 Year: 2022 Publisher: Cham Springer International Publishing :Imprint: Springer

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Keywords

Neoplasms. --- Patient-Specific Modeling. --- Precision Medicine. --- Tumor Microenvironment. --- Theranostic Nanomedicine. --- Drug Resistance, Neoplasm. --- Antineoplastic Agent Resistance --- Neoplasm Drug Resistance --- Resistance, Antineoplastic Agent --- Resistance, Antineoplastic Drug --- Antibiotic Resistance, Neoplasm --- Antineoplastic Drug Resistance --- Drug Resistance, Antineoplastic --- Photothermal Theranostics --- Nanomedicine, Theranostic --- Nanomedicines, Theranostic --- Photothermal Theranostic --- Theranostic Nanomedicines --- Cancer Microenvironment --- Cancer Microenvironments --- Microenvironment, Cancer --- Microenvironment, Tumor --- Microenvironments, Cancer --- Microenvironments, Tumor --- Tumor Microenvironments --- P Health --- P-Health --- Personalized Medicine --- Theranostics --- Individualized Medicine --- Predictive Medicine --- Medicine, Individualized --- Medicine, Personalized --- Medicine, Precision --- Medicine, Predictive --- Theranostic --- Pharmacogenomic Variants --- Pharmacogenetics --- Patient-Specific Modeling --- Patient-Specific Computational Modeling --- Physiome --- Computational Modeling, Patient-Specific --- Modeling, Patient-Specific --- Patient Specific Computational Modeling --- Patient Specific Modeling --- Physiomes --- Models, Biological --- Precision Medicine --- Benign Neoplasms --- Malignancy --- Malignant Neoplasms --- Neoplasia --- Neoplasm --- Neoplasms, Benign --- Cancer --- Tumors --- Benign Neoplasm --- Cancers --- Malignancies --- Malignant Neoplasm --- Neoplasias --- Neoplasm, Benign --- Neoplasm, Malignant --- Neoplasms, Malignant --- Tumor --- Medical Oncology --- Enginyeria biomèdica --- Resistència als medicaments --- Farmacoresistència --- Farmacologia --- Resistència a la insulina --- Efecte dels medicaments sobre els microorganismes --- Carcinomes --- Malalties neoplàstiques --- Neoplàsies --- Neoplasmes --- Patologia --- Càncer --- Feocromocitoma --- Fibromes --- Marcadors tumorals --- Mesotelioma --- Miomes --- Pòlips (Patologia) --- Sarcoïdosi --- Sarcoma --- Teratoma --- Tumors de parts toves --- Tumors en els animals --- Classificació de tumors --- Oncologia --- Quistos --- Enginyeria clínica --- Enginyeria mèdica --- Bioenginyeria --- Biofísica --- Enginyeria --- Medicina --- Electrònica mèdica --- Enginyeria de teixits --- Materials biomèdics --- Aparells i instruments mèdics --- Biomedical engineering. --- Research. --- Treatment. --- Clinical engineering --- Medical engineering --- Bioengineering --- Biophysics --- Engineering --- Medicine --- Cancer therapy --- Cancer treatment --- Cancer research --- Therapy

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