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Introduction: As anticancer intravenous chemotherapies (AIVC) are high-risk medications, there are different ways of securing the preparation circuit. In this context, the Centre Hospitalier Universitaire UCL Namur, site Godinne opted for AIVC Anticipated Circuit of Prescription and Preparation (ACPP).Purpose: to evaluate the impact of the ACPP protocol on the quality and timing of medications preparation with a primary objective of 40% decrease of the mean daily variances. Method: daily reorganization of the process chain. Ali AIVC patients over fourteen weeks were included in a before and after study. Results : 210 patients were included in the before group and 207 patients in the after group (19% of them were included in the ACPP protocol). A 21% decrease of the mean daily variances has been observed with the ACPP (p = 0.11, standard deviation ranging from 1.27 to 0.83 (p = 0.025)). The patient's mean waiting time decreased from 128 to 114 minutes (p = 0.005) between the before/after groups and to 60 minutes for the ACPP (p < 0.001). One of the 174 bags was lost in the ACPP. Discussion: the mean daily variance enabled us to observe an improvement of the timing of production without reaching our 40% decrease objective. The mean waiting time has significantly decreased but remains above 30 minutes. The losing rate in the ACPP protocol is under 2% as desired. The failure to reach our preset objectives can. be explained by the fact that the ACPP is a new concept in the clinic. Conclusion : ACPP helped to improve pharmacy activities and to decrease patients waiting time but also to keep a similar security and to avoid lasses. However, the study should be conducted on a larger cohort and over a longer period to confirm the impact of the project.

Prescriptions --- Pharmacy Service, Hospital --- Chemotherapy, Cancer, Regional Perfusion --- Administration, Intravenous