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Anesthesia. --- Bird. --- Blood. --- Cannulation. --- Catheterization. --- Collection. --- Conscious rats. --- Decapitation. --- Laboratory. --- Mammals. --- Physiological-responses. --- Prolactin. --- Stress. --- Vascular-access.

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Male Purdue-Wistar rats were handled for 20 days in infancy or were not disturbed (total N = 324). In adulthood these animals were subdivided and exposed to one of three electric shock intensities (0.2, 0.5, or 0.8 mA) for durations of 2, 5, 10, 15, 30, or 60 min. Following the termination of shock, the animals were killed immediately, 5 min afterwards, or 15 min afterwards; and the free plasma corticosterone was assayed. Both duration of shock and time between shock termination and decapitation affected the magnitude of the corticoid response; these effects were additive and permit the general conclusion that the major parameter is total time between shock onset and killing. Rats handled in infancy were found to have a greater amount of plasma corticosterone at the time that shock was terminated, but their rate of release of corticosterone during the subsequent 15 min was less than that of nonhandled controls.

Adulthood. --- Animal. --- Animals. --- Control. --- Corticosterone response. --- Corticosterone. --- Decapitation. --- Development. --- Duration. --- Electric shock. --- Function. --- Infantile stimulation. --- Male. --- Parameters. --- Plasma corticosterone. --- Plasma-corticosterone. --- Plasma. --- Rat. --- Rats. --- Release. --- Response. --- Shock. --- Stimulation. --- Stress. --- Time.