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Periodical
JAK-STAT
ISSN: 21623996 21623988 21623945 2162397X

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Book
Receptors, membrane transport and signal transduction
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ISBN: 3540504214 3642742025 3642742009 Year: 1989 Volume: vol 29 Publisher: Berlin : Springer,

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Periodical
Journal of cell communication and signaling
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ISSN: 1873961X 18739601

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Keywords

Cell interaction --- Cell Communication. --- Signal Transduction. --- Cell Biology. --- Societies, Scientific. --- Cell interaction. --- Cellular Biology --- Cytology --- Biologies, Cell --- Biologies, Cellular --- Biology, Cell --- Biology, Cellular --- Cell Biologies --- Cellular Biologies --- Cell-cell interaction --- Cell communication --- Cellular communication (Biology) --- Cellular interaction --- Intercellular communication --- American Psychological Association --- Scientific Societies --- Scientific Society --- Society, Scientific --- Receptor Mediated Signal Transduction --- Signal Transduction Pathways --- Signal Transduction Systems --- Receptor-Mediated Signal Transduction --- Signal Pathways --- Pathway, Signal --- Pathway, Signal Transduction --- Pathways, Signal --- Pathways, Signal Transduction --- Receptor-Mediated Signal Transductions --- Signal Pathway --- Signal Transduction Pathway --- Signal Transduction System --- Signal Transduction, Receptor-Mediated --- Signal Transductions --- Signal Transductions, Receptor-Mediated --- System, Signal Transduction --- Systems, Signal Transduction --- Transduction, Signal --- Transductions, Signal --- Cell Interaction --- Cell-to-Cell Interaction --- Cell Communications --- Cell Interactions --- Cell to Cell Interaction --- Cell-to-Cell Interactions --- Communication, Cell --- Communications, Cell --- Interaction, Cell --- Interaction, Cell-to-Cell --- Interactions, Cell --- Interactions, Cell-to-Cell --- Cell Communication --- Signal Transduction --- Societies, Scientific --- Receptor-CD3 Complex, Antigen, T-Cell --- Receptor Cross-Talk --- Feedback, Physiological --- Gasotransmitters --- Cellular control mechanisms --- Life Sciences --- Biology --- Cell Signaling

Cell-cell signaling in bacteria
Authors: ---
ISBN: 1555811493 9781555811495 Year: 1999 Publisher: Washington : ASM Press,


Article
Modulation of hippocampal plasticity and cognitive behavior by short-term blueberry supplementation in aged rats.

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During aging, reductions in hippocampal neurogenesis are associated with memory decline indicating a causal relationship. Indeed, insulin-like growth factor-1 (IGF-1), a major activator of the extracellular receptor kinase pathway that is central in learning and memory processes, is also a key modulator of hippocampal neurogenesis. Previously, we showed that age-related declines in spatial memory tasks can be improved by antioxidant-rich diets containing blueberries. In this study, to begin to understand the mechanisms responsible for the beneficial effects of blueberries, we assessed changes in hippocampal plasticity parameters such as hippocampal neurogenesis, extracellular receptor kinase activation, and IGF-1 and IGF-1R levels in blueberry-supplemented aged animals. Our results show that all these parameters of hippocampal neuronal plasticity are increased in supplemented animals and aspects such as proliferation, extracellular receptor kinase activation and IGF-1 and IGF-1R levels correlate with improvements in spatial memory. Therefore, cognitive improvements afforded by polyphenolic-rich fruits such as blueberries appear, in part, to be mediated by their effects on hippocampal plasticity

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