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This book describes the tools, developed by the author, for perturbing endogenous mechano-sensitive ion channels for magneto-mechanical neuro-modulation. He explores the ways in which these tools compare against existing ones such as electricity, chemicals, optogenetics, and techniques like thermos/magneto-genetics. The author also reports on two platforms—magnetic ratcheting and magnetic microfluidics for directed evolution and high throughput culture of magnetotactic bacteria—that produce high quality magnetic nanoparticles for biomedical applications like neural stimulations. This thesis was submitted to and approved by the University of California, Los Angeles. Introduces technology for non-invasive control of neural activities that offer deep tissue penetration and controllable dosage; Examines the effects of biomechanical forces on cellular functions; Explores how to improve the reproducibility and uptake of magnetic tools for non-invasive neural modulation.
Engineering. --- Nanoscale science. --- Nanoscience. --- Nanostructures. --- Biomedical engineering. --- Nanotechnology. --- Biomedical Engineering. --- Nanoscale Science and Technology. --- Neural stimulation. --- Magnetic nanoparticle hyperthermia. --- Hyperthermia, Magnetic fluid --- Hyperthermia, Magnetic nanoparticle --- Hyperthermia, Magnetic nanoparticle-based --- Magnetic fluid hyperthermia --- Magnetic nanoparticle-based hyperthermia --- MNH (Magnetic nanoparticle hyperthermia) --- Thermotherapy --- Nerve stimulation --- Stimulation, Neural --- Electric stimulation --- Electrodiagnosis --- Electrophysiology --- Electrotherapeutics --- Biomedical Engineering and Bioengineering. --- Molecular technology --- Nanoscale technology --- High technology --- Clinical engineering --- Medical engineering --- Bioengineering --- Biophysics --- Engineering --- Medicine --- Nanoscience --- Physics --- Nano science --- Nanoscale science --- Nanosciences --- Science
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In recent years, micro- and nanosystems with magnetic properties have been extensively investigated in many fields, ranging from physics to medicine. The research in these areas has lately shown that if the magnetic compounds are opportunely functionalized and modified with moieties and specific functional groups, a plethora of challenging multidisciplinary applications is available, including the development of magnetically controlled particles, stimuli-responsive materials, magnetically guided chemical/drug-delivery systems, sensors, spintronics, separation and purification of contaminated groundwater and soils, ferrofluids and magnetorheological fluids, contrast agents for MRI, and internal sources of heat for the thermoablation of cancer. Magnetic compounds have been found to be highly selective and effective in all these application fields, from the molecular level to the microscale. This book aims at underlining the latest advances in the field of magnetic compounds, nanosystems, and materials, covering a large variety of topics related to novel synthesis and functionalization methods and the properties, applications, and use of magnetic systems in chemistry, materials science, diagnostics, and medical therapy.
Research & information: general --- paramagnetic properties --- gadolinium oxide --- relaxation agents --- nanoparticles --- magnetic materials --- nanostructured materials --- magnetic nanoparticles --- magnetometry --- magnetic hysteresis --- magnetic domain visualization --- magnetic resonance imaging --- magnetic fluid hyperthermia --- magnetic particle toxicity --- magnetically-guided drug delivery systems --- magnetite nanoparticles --- magnetic resonance imaging (MRI), polymeric core–shells --- magnetic submicron core–shells --- drug delivery --- adsorption --- magnetic separation --- nanotechnology --- water treatments --- iron oxide nanoparticles --- positive contrast agents --- ligands --- molecular magnetism --- single-ion magnets (SIMs) or monometallic single-molecule magnets --- single-molecule magnets (SMMs) --- synthetic strategies --- 3d-, 4d- and 5d-metal complexes as SIMs and SMMs --- heavy metals --- nanocomposite --- hybrid --- multi-metal --- water --- magnetic particle and nanoparticles --- single-molecule magnets --- MRI contrast agents
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In recent years, micro- and nanosystems with magnetic properties have been extensively investigated in many fields, ranging from physics to medicine. The research in these areas has lately shown that if the magnetic compounds are opportunely functionalized and modified with moieties and specific functional groups, a plethora of challenging multidisciplinary applications is available, including the development of magnetically controlled particles, stimuli-responsive materials, magnetically guided chemical/drug-delivery systems, sensors, spintronics, separation and purification of contaminated groundwater and soils, ferrofluids and magnetorheological fluids, contrast agents for MRI, and internal sources of heat for the thermoablation of cancer. Magnetic compounds have been found to be highly selective and effective in all these application fields, from the molecular level to the microscale. This book aims at underlining the latest advances in the field of magnetic compounds, nanosystems, and materials, covering a large variety of topics related to novel synthesis and functionalization methods and the properties, applications, and use of magnetic systems in chemistry, materials science, diagnostics, and medical therapy.
paramagnetic properties --- gadolinium oxide --- relaxation agents --- nanoparticles --- magnetic materials --- nanostructured materials --- magnetic nanoparticles --- magnetometry --- magnetic hysteresis --- magnetic domain visualization --- magnetic resonance imaging --- magnetic fluid hyperthermia --- magnetic particle toxicity --- magnetically-guided drug delivery systems --- magnetite nanoparticles --- magnetic resonance imaging (MRI), polymeric core–shells --- magnetic submicron core–shells --- drug delivery --- adsorption --- magnetic separation --- nanotechnology --- water treatments --- iron oxide nanoparticles --- positive contrast agents --- ligands --- molecular magnetism --- single-ion magnets (SIMs) or monometallic single-molecule magnets --- single-molecule magnets (SMMs) --- synthetic strategies --- 3d-, 4d- and 5d-metal complexes as SIMs and SMMs --- heavy metals --- nanocomposite --- hybrid --- multi-metal --- water --- magnetic particle and nanoparticles --- single-molecule magnets --- MRI contrast agents
Choose an application
In recent years, micro- and nanosystems with magnetic properties have been extensively investigated in many fields, ranging from physics to medicine. The research in these areas has lately shown that if the magnetic compounds are opportunely functionalized and modified with moieties and specific functional groups, a plethora of challenging multidisciplinary applications is available, including the development of magnetically controlled particles, stimuli-responsive materials, magnetically guided chemical/drug-delivery systems, sensors, spintronics, separation and purification of contaminated groundwater and soils, ferrofluids and magnetorheological fluids, contrast agents for MRI, and internal sources of heat for the thermoablation of cancer. Magnetic compounds have been found to be highly selective and effective in all these application fields, from the molecular level to the microscale. This book aims at underlining the latest advances in the field of magnetic compounds, nanosystems, and materials, covering a large variety of topics related to novel synthesis and functionalization methods and the properties, applications, and use of magnetic systems in chemistry, materials science, diagnostics, and medical therapy.
Research & information: general --- paramagnetic properties --- gadolinium oxide --- relaxation agents --- nanoparticles --- magnetic materials --- nanostructured materials --- magnetic nanoparticles --- magnetometry --- magnetic hysteresis --- magnetic domain visualization --- magnetic resonance imaging --- magnetic fluid hyperthermia --- magnetic particle toxicity --- magnetically-guided drug delivery systems --- magnetite nanoparticles --- magnetic resonance imaging (MRI), polymeric core–shells --- magnetic submicron core–shells --- drug delivery --- adsorption --- magnetic separation --- nanotechnology --- water treatments --- iron oxide nanoparticles --- positive contrast agents --- ligands --- molecular magnetism --- single-ion magnets (SIMs) or monometallic single-molecule magnets --- single-molecule magnets (SMMs) --- synthetic strategies --- 3d-, 4d- and 5d-metal complexes as SIMs and SMMs --- heavy metals --- nanocomposite --- hybrid --- multi-metal --- water --- magnetic particle and nanoparticles --- single-molecule magnets --- MRI contrast agents --- paramagnetic properties --- gadolinium oxide --- relaxation agents --- nanoparticles --- magnetic materials --- nanostructured materials --- magnetic nanoparticles --- magnetometry --- magnetic hysteresis --- magnetic domain visualization --- magnetic resonance imaging --- magnetic fluid hyperthermia --- magnetic particle toxicity --- magnetically-guided drug delivery systems --- magnetite nanoparticles --- magnetic resonance imaging (MRI), polymeric core–shells --- magnetic submicron core–shells --- drug delivery --- adsorption --- magnetic separation --- nanotechnology --- water treatments --- iron oxide nanoparticles --- positive contrast agents --- ligands --- molecular magnetism --- single-ion magnets (SIMs) or monometallic single-molecule magnets --- single-molecule magnets (SMMs) --- synthetic strategies --- 3d-, 4d- and 5d-metal complexes as SIMs and SMMs --- heavy metals --- nanocomposite --- hybrid --- multi-metal --- water --- magnetic particle and nanoparticles --- single-molecule magnets --- MRI contrast agents
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