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Thrombosis --- Blood platelets --- Blood platelet aggregation --- Blood-vessels --- Endothelium

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Membrane Lipids --- Phospholipids --- Platelet Aggregation --- Blood Platelets --- metabolism --- metabolism --- physiology

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Vaso-occlusive disorders including unstable angina, myocardial infarction, transient ischemic attacks, stroke and peripheral artery disease remain the major sources of morbidity and mortality in western civilization. Platelet activation and resulting platelet aggregation play a major role in the pathogenesis of these thromboembolic diseases. Recognition of the contribution of platelets to the pathophysiology of cardiovascular disease has provided impetus for the continued search for new antiplatelet agents. Hence, over the past two decades many strategies have been evaluated in the search for

Pharmaceutical chemistry --- Congresses --- Chemistry --- Physical sciences --- Chimie pharmaceutique --- Platelet Aggregation Inhibitors

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Platelet Aggregation --- Blood Platelets --- Cardiopulmonary Bypass --- Blood Cell Count --- drug effects --- drug effects

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Tissue Plasminogen Activator --- Platelet Aggregation --- Streptokinase --- Azo Compounds --- Diamide --- pharmacology --- drug effects --- pharmacology --- pharmacology --- pharmacology