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HEPARITIN SULFATE --- LIVER --- PROSTATE --- FIBROBLAST GROWTH FACTOR --- HEPARITIN SULFATE --- LIVER --- PROSTATE --- FIBROBLAST GROWTH FACTOR

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Fibroblast growth factors. --- Receptors, Fibroblast Growth Factor. --- Fibroblast Growth Factor 2. --- Cartilage-Derived Growth Factor --- Class II Heparin-Binding Growth Factor --- FGF-2 --- FGF2 --- Fibroblast Growth Factor-2 --- Heparin-Binding Growth Factor Class II --- Prostate Epithelial Cell Growth Factor --- Prostatropin --- Basic Fibroblast Growth Factor --- Fibroblast Growth Factor, Basic --- HBGF-2 --- Cartilage Derived Growth Factor --- FGF 2 --- FGF Receptor --- Fibroblast Growth Factor Receptor --- Heparin-Binding Growth Factor Receptor --- FGF Receptors --- Fibroblast Growth Factor Receptors --- Receptors, FGF --- Heparin Binding Growth Factor Receptor --- Receptor, FGF --- Fibroblast Growth Factors --- Fibroblast growth factor --- Growth factors --- Mitogens

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This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact

Science: general issues --- Pharmacology --- FGF (fibroblast growth factor) --- regeneration --- development --- metabolic regulation --- ischema-reperfusion injury

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Fibroblast Growth Factors. --- DNA Synthesis Factor --- Fibroblast Growth Factor --- Fibroblast Growth Regulatory Factor --- Growth Factor, Fibroblast --- Growth Factors, Fibroblast --- Fibroblast growth factors --- Congresses. --- congresses. --- Fibroblast Growth Factors --- Fibroblast growth factor --- Growth factors --- Mitogens --- Congresses --- Fibroblast growth factors - Congresses. --- FIBROBLAST GROWTH FACTOR --- CONGRESSES

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The fibroblast growth factors (FGFs) represent one of the relatively few families of extracellular signalling peptides that have been shown in recent decades to be key regulators of metazoan development. FGFs are required for multiple processes in both protostome and deuterostome groups. Given the wide range of regulatory roles attributed to the FGFs, it is perhaps not surprising that misregulation of this signalling pathway has been implicated in a number of human disease conditions. The focus of the present review is to look at the fundamental components of the FGF pathway and illustrate how this highly conserved regulatory cassette has been deployed to regulate multiple, diverse processes during vertebrate development. This review will explore examples from several vertebrate model organisms and include discussions of the role of FGF signalling in regulating the establishment of the mesoderm, neural patterning, morphogenesis, myogenesis, limb development, and the establishment of right-left asymmetry.

Fibroblast growth factors. --- Vertebrates -- Development. --- Vertebrates -- Growth & development. --- Fibroblast Growth Factors --- Chordata --- Intercellular Signaling Peptides and Proteins --- Animals --- Biological Factors --- Proteins --- Eukaryota --- Peptides --- Amino Acids, Peptides, and Proteins --- Organisms --- Chemicals and Drugs --- Fibroblast Growth Factor 1 --- Vertebrates --- Zoology --- Human Anatomy & Physiology --- Health & Biological Sciences --- Animal Biochemistry --- Animal Anatomy & Embryology --- Growth factors. --- Growth. --- Fibroblast Growth Factors. --- growth & development. --- Fibroblast growth factor --- Mesoderm --- Neurectoderm --- Xenopus --- Organogenesis --- Somites --- Limb --- MyoD --- Somitogenesis --- Morphogenesis --- Left-right asymmetry --- MAPK --- Sprouty --- ERK --- Map kinase phosphatase --- Signal transduction