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Huntington's disease
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ISBN: 1283579944 9786613892393 0191549681 0191607371 9780191549687 9780199212019 0199212015 9781283579940 Year: 2008 Publisher: Oxford Oxford University Press

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Abstract

Huntington's disease is a genetically inherited condition which results in severe nerve-cell damage in the brain. The hereditary and debilitative nature of the disease means that many people are involved either directly or indirectly by this condition. The recent identification of the faulty gene involved has made the diagnosis of this condition simpler. The majority of people develop the disease between the ages of 35 and 55 years, so for those aware of their genetic risk there aredilemmas to consider - should you have a test to see if you have the gene? Should you start a family?The new edit


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Juvenile Huntington's disease
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ISBN: 0191753211 1283582198 9786613894649 0191575283 9780191575280 9781283582193 9780199236121 0199236127 9780191753213 6613894648 Year: 2009 Publisher: Oxford New York Oxford University Press

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Abstract

Huntington's disease (HD) is an inherited progressive neurodegenerative disorder. Although onset of Huntington's Disease usually occurs in adulthood, the age of onset of the condition is extremely variable with approximately 5-10% of cases having an onset of less than 20 years, or Juvenile Huntington's Disease (JHD). While JHD shares many of the clinical features of adult HD (e.g., chorea and personality disorders), patients with JHD often experience additional problems includingseizures, dystonia and Parkinsonism. Diagnosis in patients with JHD is often delayed because of the failure of clini

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