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This Special Issue covers both the in vitro and in vivo evaluation of marine carotenoids with anti-inflammatory and anticancer activities as well as clinical trials conducted in humans. Among the properties of carotenoids discussed in this book, it is worth highlighting the potential of astaxanthin and its precursor metabolite, adonixanthin, since oral administration of these carotenoids has shown beneficial effects on glioblastoma for the first time by suppressing cell proliferation and migration. In addition, astaxanthin has been shown to inhibit Helicobacter pylori-induced gastric carcinoma cell motility and, consequently, cancer progression through the inhibition of cytoskeleton reorganization. In addition, a carotenoid-containing lipid extract of Gloeothece sp. has demonstrated antioxidant, anti-inflammatory, and anticancer properties in vitro.

Helicobacter pylori --- gastric carcinoma --- astaxanthin --- cell motility --- cell migration --- bioavailability --- carotenoids --- marine --- nanoformulation --- oxidative stress --- reactive oxygen species --- brain --- cancer --- oral administration --- paracoccsu carotinifaciens --- xanthophyll carotenoid --- photodamage --- skin cancer --- photoaging --- marine carotenoids --- fucoxanthin --- xanthophylls --- natural compounds --- algae --- bioactive --- health --- neuroprotective agent --- neuroinflammation --- neurological diseases --- microalgae --- inflammation --- breast cancer --- bacterioruberin --- antioxidant --- pro-oxidant --- lutein --- β-carotene --- linolenic acid --- linoleic acid --- lipidic compounds --- PUFAs

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This Special Issue covers both the in vitro and in vivo evaluation of marine carotenoids with anti-inflammatory and anticancer activities as well as clinical trials conducted in humans. Among the properties of carotenoids discussed in this book, it is worth highlighting the potential of astaxanthin and its precursor metabolite, adonixanthin, since oral administration of these carotenoids has shown beneficial effects on glioblastoma for the first time by suppressing cell proliferation and migration. In addition, astaxanthin has been shown to inhibit Helicobacter pylori-induced gastric carcinoma cell motility and, consequently, cancer progression through the inhibition of cytoskeleton reorganization. In addition, a carotenoid-containing lipid extract of Gloeothece sp. has demonstrated antioxidant, anti-inflammatory, and anticancer properties in vitro.

Medicine --- Helicobacter pylori --- gastric carcinoma --- astaxanthin --- cell motility --- cell migration --- bioavailability --- carotenoids --- marine --- nanoformulation --- oxidative stress --- reactive oxygen species --- brain --- cancer --- oral administration --- paracoccsu carotinifaciens --- xanthophyll carotenoid --- photodamage --- skin cancer --- photoaging --- marine carotenoids --- fucoxanthin --- xanthophylls --- natural compounds --- algae --- bioactive --- health --- neuroprotective agent --- neuroinflammation --- neurological diseases --- microalgae --- inflammation --- breast cancer --- bacterioruberin --- antioxidant --- pro-oxidant --- lutein --- β-carotene --- linolenic acid --- linoleic acid --- lipidic compounds --- PUFAs --- Helicobacter pylori --- gastric carcinoma --- astaxanthin --- cell motility --- cell migration --- bioavailability --- carotenoids --- marine --- nanoformulation --- oxidative stress --- reactive oxygen species --- brain --- cancer --- oral administration --- paracoccsu carotinifaciens --- xanthophyll carotenoid --- photodamage --- skin cancer --- photoaging --- marine carotenoids --- fucoxanthin --- xanthophylls --- natural compounds --- algae --- bioactive --- health --- neuroprotective agent --- neuroinflammation --- neurological diseases --- microalgae --- inflammation --- breast cancer --- bacterioruberin --- antioxidant --- pro-oxidant --- lutein --- β-carotene --- linolenic acid --- linoleic acid --- lipidic compounds --- PUFAs

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The Special Issue “Marine Anti-Inflammatory and Antioxidants Agents 2021” collected the latest research, both in vitro and in vivo, on natural compounds from a variety of deep-sea organisms with anti-inflammatory and/or antioxidant properties as potential candidates for new drug discovery, and more generally for the field of marine biotechnology. The research presented here discusses the potential benefits of certain peptides and proteins derived from oysters, blue mussels, and cyanobacteria, as well as the carotenoid pigment astaxanthin, which is found in a variety of marine organisms. This Special Issue has carved out an important space for crude extracts from marine products, such as microalgae and green algae, highlighting their potential benefits to human health. Finally, the Special Issue includes a review of the benefits of some natural compounds derived from the algal biome against inflammatory bowel diseases, as well as a research article identifying the presence of the OvoA gene in arthropods for the first time. Through an excursus of high-quality research, this Special Issue provides the entire scientific community with new tools and insights to catch a molecular treasure for human health from the sea.

Medicine --- Pharmacology --- algal biome --- polysaccharides --- bioactive entities --- engineered cues --- therapeutic attributes --- inflammatory bowel disease --- microalgae --- Tisochrysis lutea --- fucoxanthin --- inflammation --- RAW 264.7 --- microRNA --- astaxanthin --- dendritic cells --- sepsis --- immune dysfunction --- lipopolysaccharide --- oxidative stress --- Ulva lactuca --- polysaccharide --- D-galactose --- kidney --- oyster peptides --- spermatogenesis --- apoptosis --- hormone --- testis --- C-phycoerythrin --- Phormidium persicinum --- acute kidney injury --- mercury --- endoplasmic reticulum stress --- bioactive peptide --- cytoprotective --- endothelial dysfunction --- blue mussel --- acute liver injury --- ferroptosis --- oyster --- peptide --- pyroptosis --- zooplankton --- natural products --- antioxidant --- transcriptome mining --- n/a

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The Special Issue “Marine Anti-Inflammatory and Antioxidants Agents 2021” collected the latest research, both in vitro and in vivo, on natural compounds from a variety of deep-sea organisms with anti-inflammatory and/or antioxidant properties as potential candidates for new drug discovery, and more generally for the field of marine biotechnology. The research presented here discusses the potential benefits of certain peptides and proteins derived from oysters, blue mussels, and cyanobacteria, as well as the carotenoid pigment astaxanthin, which is found in a variety of marine organisms. This Special Issue has carved out an important space for crude extracts from marine products, such as microalgae and green algae, highlighting their potential benefits to human health. Finally, the Special Issue includes a review of the benefits of some natural compounds derived from the algal biome against inflammatory bowel diseases, as well as a research article identifying the presence of the OvoA gene in arthropods for the first time. Through an excursus of high-quality research, this Special Issue provides the entire scientific community with new tools and insights to catch a molecular treasure for human health from the sea.

algal biome --- polysaccharides --- bioactive entities --- engineered cues --- therapeutic attributes --- inflammatory bowel disease --- microalgae --- Tisochrysis lutea --- fucoxanthin --- inflammation --- RAW 264.7 --- microRNA --- astaxanthin --- dendritic cells --- sepsis --- immune dysfunction --- lipopolysaccharide --- oxidative stress --- Ulva lactuca --- polysaccharide --- D-galactose --- kidney --- oyster peptides --- spermatogenesis --- apoptosis --- hormone --- testis --- C-phycoerythrin --- Phormidium persicinum --- acute kidney injury --- mercury --- endoplasmic reticulum stress --- bioactive peptide --- cytoprotective --- endothelial dysfunction --- blue mussel --- acute liver injury --- ferroptosis --- oyster --- peptide --- pyroptosis --- zooplankton --- natural products --- antioxidant --- transcriptome mining --- n/a

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Carotenoids are a group of approximately 600 compounds synthesized by photosynthetic organisms. These pigments are abundant in fruits and vegetables, as well as in certain animal products such as eggs and salmon, being responsible for their colorful appearance. The bioactive properties of certain carotenoids in human health are clear, as some of these compounds have antioxidant properties and serve as the only precursors of vitamin A in nature. The aim of this Special Issue entitled “Carotenoids and Human Health” is to provide the scientific community with an updated perspective of this exciting and growing research area. We compiled 19 papers from some of the most prominent scientists in the carotenoid field, including seven literature reviews and 12 original publication, covering topics such as cancer, obesity, vision, cognitive function, and skin health.

membrane transporters --- RAR --- browning --- astaxanthin --- Vitamin A --- case-control study --- ?-carotene --- transcriptomic analysis --- new-born --- carotenes --- cancer-related cognitive impairment --- androgen --- beta-carotene --- eicosapentanoic acid --- mango by-products --- mangiferin --- cell culture --- chronic disease --- Akkermansia --- animal --- intestine --- carotenoids --- alcoholic fatty liver disease --- Phaeodactylum tricornutum --- carotenoid --- tomato --- colourless carotenoids --- preterm mothers --- inflammation --- ?-Cryptoxanthin --- adipocytes --- vitamin A --- gastric cancer --- food ingredients --- brain --- gut microbiota --- zeaxanthin --- nutricosmetics --- brown adipose tissue --- bioactive compounds --- breastfeeding --- aging --- oxidative stress --- retinoids --- phytofluene --- glaucoma --- H. pylori --- retinoid --- tomato extract --- retinol --- ?-cryptoxanthin --- microalgae --- fucoxanthin --- obesity --- macular pigment --- carotene --- photoprotection --- adipose tissue --- lutein --- metabolic syndrome --- Caenorhabditis elegans --- functional foods --- beta-cryptoxanthin --- retinoic acid --- nutrition --- lycopene --- bioavailability --- nutraceuticals --- adipocyte --- ?-tocopherol --- phytoene --- memory --- cosmeceuticals --- antioxidants --- mature milk --- RXR --- fat reduction --- xanthophylls --- colostrum --- smoking --- overweight --- provitamin A --- public health --- Korea --- ?-carotene oxygenase 1 --- cognition --- full-term mothers --- hippocampus --- alpha-carotene --- prostate cancer --- hypertension