Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Extracellular Vesicles --- Extracellular Matrix --- Coated vesicles --- Cytology --- Extracellular matrix --- Extracellular Vesicles. --- Extracellular Matrix.

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact

myokines --- exercise --- muscle-derived secreted factors --- circulating miRNA --- extracellular vesicles

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Extracellular Vesicles --- Extracellular Matrix --- Coated vesicles --- Cytology --- Extracellular matrix --- Coated vesicles. --- Cytology. --- Extracellular matrix. --- Extracellular Vesicles. --- Extracellular Matrix.

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact

Science: general issues --- Physiology --- myokines --- exercise --- muscle-derived secreted factors --- circulating miRNA --- extracellular vesicles

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Plasticity is the hallmark of stem cells. At the same time, stem cells, like any other cell type, are influenced by their microenvironment and respond to it accordingly. A specific microenvironment is defined by a variety of factors, including biological and chemical factors, cell-cell interactions, but also metabolic and mechanical cues. Such dynamic and specialized microenvironment where the stem cells reside is considered a stem cell niche. Tissue injury as well as malignant tissue alterations lead to changes in the niche influencing the plasticity and biology of residing stem cells. Similarly, the niche changes upon tissue damage, which eventually induces differentiation of stem cells and ultimately regeneration of the tissue.

microenvironment --- stem cells --- tissue regeneration --- immunomodulation --- extracellular vesicles (EVs) --- oxygen tension --- plasticity --- imaging