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The concept of endocarditis has evolved significantly over the years. While initially associated with patients with advanced co-morbidities, such as renal failure and chronic immunosuppression, endocarditis now spans many diverse disciplines. As such, the importance of advanced diagnostic imagining tools, a better understanding of the pathophysiology of not only the infectious (and non-infectious) disease process but also of cardiac structural abnormalities, and the growing literature on management cannot be underemphasized. This book broadens our collective understanding of the spectrum of diagnostic and therapeutic challenges that all areas of medicine must appreciate when faced with the challenging clinical problem of endocarditis.

Endocarditis.

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Endocarditis. --- Endocarditis --- Auscultation. --- History.

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Endocarditis, Bacterial

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Infective endocarditis is a devastating disease that affects the heart´s inner lining, typically due to bacterial infections. The infection harms the valves, causing them to leak, and creates clots that move to other organs, including the brain. Patients with congenital heart disease and prosthetic valves and those who use intravenous drugs are at considerable risk. Surgical procedures and dental extraction may lead to endocarditis in vulnerable patients. The management of endocarditis involves a multidisciplinary team that includes a cardiologist and infectious disease specialists with competence in echocardiography and other imaging as well as thoracic surgery. This book explores diverse aspects of infective endocarditis and discusses recent advances in its diagnosis and treatment.

Endocarditis. --- Diagnosis.

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Endocarditis is an inflammation of the lining of the heart and valves. It can be due to a non-infectious cause but when the inflammation is associated with an infection, usually bacterial, it is known as infective endocarditis. It is typically characterized by the development of a large septic thrombus on one of the cardiac valves. As this thrombus grows, it can lead to valve failure or may fragment forming a septic embolus that is associated with high mortality if the target of the embolus is the brain, heart or lung. This book reviews multi-organ complications associated with Infective endocarditis including significant recent advances in molecular mechanisms underlying thrombus formation on the cardiac valve, anti-microbial treatment and surgery.

Infective endocarditis. --- Bacterial endocarditis --- Endocarditis, Bacterial --- Infectious endocarditis --- Endocarditis --- Heart --- Infections --- Cardiovascular medicine