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While the first edition of the critically acclaimed and highly popular Circadian Physiologyoffered a concise but rigorous review of basic and applied research on circadian rhythms, this newest edition provides educators with the primary textbook they need to support a course on this cutting-edge topic. Maintaining the same accessible multidisciplinary approach of the original, this volume provides a thorough grounding in a broad range of topics, while offering instructors many unique advantages. This impressive handbook provides the foundation, along with the supplementary material, and all the implementation details necessary to run a cutting-edge class on an exceptionally timely and intriguing topic. This edition of Circadian Physiologynot only updates the material covered in the original, but it also expands its length and scope, presenting many new findings, such as the discovery of new retinal photoreceptors, the identification of several non-hypothalamic circadian pacemakers, and the elucidation of genomic and proteomic mechanisms of biological timing. Three times the length of the original, this volume includes approximately 730 figures and 5,000 bibliographic references, making it a true handbook of circadian physiology.
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Providing an up-to-date overview of the field, this state-of-the-art reference details how sleep and circadian rhythms are interconnected, revealing the impact of various disease states on, and the molecular and genetic basis for, disrupted sleep and circadian rhythmicity and their effects on physical and mental health, safety, performance, and productivity. Integrates current and rapidly advancing discoveries of sleep and circadian rhythms! Offering an integrative approach to research findings from basic science to clinical points of view, Regulation of Sleep and Circadian Rhythms discussesthe three developmental stages of sleep in mammals the evolution of circadian timing brainstem regulation of sleep non-REM sleep and thalamocortical function cognitive correlates of behavioral states dysfunctional sleep sleep homeostasis neuroanatomy of circadian control acute effects of light organization of vertebrate circadian timing systems production, sites, and mechanisms of melatonin genetic aspects of pathological human sleep sleep alterations associated with age, disease, and psychiatric state and more! Complete with over 3200 references, tables, and figures, Regulation of Sleep and Circadian Rhythms is an essential resource for clinical neurologists and neurobiologists, pulmonologists, psychiatrists and behavioral scientists, endocrinologists and neuroendocrinologists, chronobiologists, sleep specialists, general medicine practitioners and internists, gerontologists, psychologists, and graduate and medical school students in these disciplines.
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