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Fast Facts: Hypertension provides a concise readable refresher on this common and potentially devastating condition.

Hypertension. --- Blood pressure, High --- High blood pressure --- Vascular hypertension --- Blood circulation disorders

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Hypertension, known as a "silent killer" is widely prevalent and a major risk factor for cardiovascular diseases. It afflicts more than one billion population worldwide and is a leading cause of morbidity and mortality. The authors of the chapters look from different angles to hypertension, sharing their new knowledge and experience in the direction of deep understanding and more clarification of the disease providing an invaluable resource not only for clinicians, but also for all medical sciences students and health providers.

Hypertension. --- Blood pressure, High --- High blood pressure --- Vascular hypertension --- Blood circulation disorders --- Pharmacology

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Primary care physicians have a leading role to play in screening for hypertension and ensuring that patients receive the most appropriate treatment. Fast Facts: Hypertension provides a concise readable refresher on this common and potentially devastating condition.

Hypertension. --- Blood pressure, High --- High blood pressure --- Vascular hypertension --- Blood circulation disorders

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Essential hypertension is still an important health care problem. It is necessary to investigate its mechanisms in animal models. The potential clinical importance of such experimental research might be expected. This Special Issue concerned several important topics. First, several studies focused on the pathophysiological mechanisms responsible for blood pressure elevation during hypertension development, organ damage in chronic hypertension, and drugs targeting hypertension and/or its complications. Other studies were interested in the participation of central and peripheral blood pressure control, changes in vascular structure and function, and neural, humoral, and endocrine factors. Furthermore, the contribution of altered redox signaling, chronic inflammation, microbiome changes, and interactions of genetic and environmental factors were evaluated in multiple papers. Finally, special attention was paid to the progress in pharmacological tools for the control of hypertension and associated organ damage, genetic modifications to alter blood pressure levels, and non-pharmacological interventions attenuating hypertension or its complications. The original articles or reviews covered the interesting aspects of the pathophysiology of hypertension and associated end-organ damage, the use of various experimental hypertensive models, and the importance of specific environmental factors acting in distinct phases of the ontogeny. We especially appreciate the presentation of new ideas and the critical discussion of traditional theories.

Hypertension. --- Blood pressure, High --- High blood pressure --- Vascular hypertension --- Blood circulation disorders

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Hypertension --- physiopathology --- therapy --- Blood pressure, High --- High blood pressure --- Vascular hypertension --- Blood circulation disorders --- physiopathology. --- therapy. --- Hypertension - physiopathology --- Hypertension - therapy