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Toxicity testing.

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The approach of this project was based on the assumption that relevant toxicity data can be extracted from the risk-phrases that have been assigned to the chemical substances and published on official and advisory lists, and that this information can be transformed into one figure representing the level of toxicity. The overall purpose of this project was to facilitate the integration of the assessment of chemical substances in Life Cycle Assessment. This is put into practice by the following tasks: Establish a database with data on human toxicity and ecotoxicity for chemical substances derived from risk-phrases. Establish a software that can calculate effect factors according to the EDIP Methodology from these data. It was furthermore the purpose to apply this model to calculate effect factors for substances present on official - and advisory lists.

Toxicity testing.

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Toxicity testing

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First published in 1989, this book acknowledges that new drugs, food additives and other compounds need to be carefully screened for toxic side-effects. The bulk of this study is devoted to the practical questions of 'what toxicological studies should we perform?' and 'how should we perform them?' Compounds which undergo toxicity testing may be conveniently categorised as those which are intended for administration to man and those which are not. The former include pharmaceuticals to be used medicinally or prophylactically and chemicals which are added to our food, drinks or medicine to improve their stability, appearance or palatability. Since it is on pharmaceuticals that the most comprehensive toxicological evaluations are generally performed, this book has been directed primarily towards to toxicological evaluation of potential new drugs. The principles and methodology of toxicological evaluation of other types of compounds are essentially similar.

Toxicity testing.

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This assessment is a toxicity assessment developed by the U.S. EPA's Office of Research and Development (ORD) Center for Public Health and Environmental Assessment (CPHEA). A provisional peer-reviewed toxicity value (PPRTV) is defined as a toxicity value derived for use in the Superfund Program. This assessment for perfluorobutane sulfonic acid (PFBS) updates and replaces the 2014 PPRTV assessment for PFBS.

Toxicity testing.