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Respiratory syncytial virus (RSV) was first identified half a century ago in 1956. Following its discovery, the virus soon became recognised as a major viral pathogen causing extensive outbreaks of respiratory tract infections in both the very young and in vulnerable adults. It is an unusual virus in that it can cause repeated reinfections throughout life. The topics covered within this volume are wide ranging in scope from the most basic molecular biology of the virus to the clinical picture of RSV in the developing world. The internationally recognised experts were invited not only to revi
Respiratory organs --- Respiratory syncytial virus. --- Diseases. --- Pseudomyxoviruses --- Respiratory diseases --- Paramyxoviruses
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Respiratory organs --- Respiratory syncytial virus. --- Diseases. --- Pseudomyxoviruses --- Paramyxoviruses --- Respiratory diseases
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In this online Open Access book on "Human RSV Infections", several distinguished authors contribute their experience in respiratory syncytial virology. A major focus lies on the fascinating pathophysiology of RSV and represents recent and actual work on different mechanisms involved in the complex pathogenesis of the virus. The second section elucidates epidemiologic and diagnostic aspects of RSV infection covering a more clinical view of RSV disease. At last, treatment modalities including the search for a vaccine that is still not in sight are discussed and conclude this book, thus building up a circle that runs from experimental models of RSV related lung disease over clinical aspects of disease to the latest news of therapeutic and prophylactic approaches to human RSV infection.
Respiratory infections. --- Respiratory syncytial virus. --- Pseudomyxoviruses --- Paramyxoviruses --- Respiratory organs --- Respiratory tract infections --- Upper respiratory infections --- Upper respiratory tract infections --- Infection --- Infections --- Diseases --- Infectious & contagious diseases
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Although respiratory syncytial virus (RSV) has been a high priority for vaccine development for over 50 years now, still no vaccine is available and none has yet demonstrated sufficient promise to move to licensure. The success of RSV immune prophylaxis and the availability of ever more powerful tools to study the immune response and pathogenesis of disease, combined with the ability to construct a wide variety of vaccines using different vaccine platforms, give us grounds to believe that an RSV vaccine is within reach. This book brings together in one source what is currently known about the virus: its clinical and epidemiologic features; the host response and pathogenesis of the disease; vaccines, vaccine platforms, and treatment; and animal and tissue culture models of RSV infection. It is designed to organize the critical information relevant to RSV vaccine development, facilitate the assimilation of data, and speed progress toward producing a safe and effective vaccine.
Emerging infectious diseases. --- Medicine. --- Vaccines. --- Models, Animal --- Pneumovirus Infections --- Models, Biological --- Animal Diseases --- Viral Vaccines --- Investigative Techniques --- Vaccines --- Paramyxoviridae Infections --- Models, Theoretical --- Diseases --- Biological Products --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Mononegavirales Infections --- RNA Virus Infections --- Complex Mixtures --- Chemicals and Drugs --- Virus Diseases --- Disease Models, Animal --- Respiratory Syncytial Virus Vaccines --- Respiratory Syncytial Virus Infections --- Biology --- Health & Biological Sciences --- Microbiology & Immunology --- Respiratory syncytial virus --- Respiratory organs --- Vaccination. --- Diseases. --- Respiratory diseases --- Emerging infections --- New infectious diseases --- Re-emerging infectious diseases --- Reemerging infectious diseases --- Pseudomyxoviruses --- Virology. --- Infectious diseases. --- Pediatrics. --- Biomedicine. --- Vaccine. --- Infectious Diseases. --- Pneumology/Respiratory System. --- Biologicals --- Paediatrics --- Pediatric medicine --- Medicine --- Children --- Microbiology --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Medical sciences --- Pathology --- Physicians --- Health and hygiene --- Communicable diseases --- Paramyxoviruses --- Medical virology. --- Pneumology. --- Medical microbiology --- Virology --- Virus diseases --- Respiratory organs—Diseases. --- Pharmacology. --- Human beings --- Illness --- Illnesses --- Morbidity --- Sickness --- Sicknesses --- Epidemiology --- Health --- Sick --- Drug effects --- Medical pharmacology --- Chemicals --- Chemotherapy --- Drugs --- Pharmacy --- Physiological effect
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