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Piperidine : structure, preparation, reactivity, and synthetic applications of piperidine and its derivates
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ISBN: 0444883487 1322269203 148329093X 9780444883483 Year: 1991 Volume: 43 Publisher: Amsterdam: Elsevier,

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Abstract

Piperidine, one of the simplest heterocyclic systems, is found in nature as part of several alkaloid compounds. Both natural and especially unnatural piperidine derivatives present interesting pharmacological properties. From a structural viewpoint, the conformation of piperidine has been the subject of one of the fiercest controversies in structural organic chemistry in the last few years. As a result of the combined use of several spectroscopic techniques, the conformational behavior of most types of piperidine-related compounds has been clarified. Some piperidine derivatives, namely, N-acyl


Multi
Piperidine-based drug discovery
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ISBN: 9780128134283 0128134283 9780128051573 0128051574 Year: 2017 Publisher: Amsterdam, Netherlands : Elsevier,

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Piperidine-Based Drug Discovery outlines the complexities of Piperidine scaffold use in drug discovery, including derivative chemistry, structural properties, methods of synthesis and practical implementations. Piperidine scaffolds are the cornerstones of over 70 commercialized drugs (including multiple blockbusters). Designed as a guide for both experts and students working in this and related areas, it is hoped that this volume will encourage and inspire the continued design and development of novel pharmaceuticals based on Piperidine and its derivatives. Heterocyclic compounds are of central importance to medicinal chemistry, as demonstrated by the high percentage of marketable drugs that feature heterocyclic fragments in their structures. As starting points for drug discovery they offer a broad range of attractive properties, and a detailed understanding of the particular characteristics of each is of great benefit to researchers. The most commonly used heterocycle among US FDA approved pharmaceuticals, Piperidine is an extremely important building block in the synthesis of medicinal agents. This heterocycle and its derivatives exhibit a number of important functionalities and have been employed variously as CNS modulators, antiaggregants, anticoagulants, antihistamines, anti-cancer drugs and analgesics.


Dissertation
Préparation et introduction de motifs pseudolipidiques dans des peptides de synthèse : induction "in vivo" d'une réponse immune T cytotoxique spécifique.
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Year: 1990

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Book
Piperidine-based drug discovery
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ISBN: 0128134283 0128051574 9780128134283 9780128051573 Year: 2017 Publisher: Amsterdam, Netherlands

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Book
Modern selective fungicides : Properties, applications, mechanisms of action.
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ISBN: 3334604551 Year: 1995 Publisher: Jena : Gustav Fischer,

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Book
Ritalin : theory and practice
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ISBN: 0585211434 Year: 2000 Publisher: [Place of publication not identified] M A Liebert Publishers

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Keywords

Methylphenidate --- Attention-deficit hyperactivity disorder --- Pharmacology --- Drug Therapy --- Attention Deficit Disorder with Hyperactivity --- Piperidines --- Biological Science Disciplines --- Attention Deficit and Disruptive Behavior Disorders --- Phenylacetates --- Therapeutics --- Heterocyclic Compounds, 1-Ring --- Mental Disorders Diagnosed in Childhood --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Acids, Carbocyclic --- Natural Science Disciplines --- Mental Disorders --- Carboxylic Acids --- Disciplines and Occupations --- Heterocyclic Compounds --- Chemicals and Drugs --- Organic Chemicals --- Psychiatry and Psychology --- Pediatrics --- Medicine --- Health & Biological Sciences --- Chemotherapy --- Organic Chemical --- Chemical, Organic --- Chemicals, Organic --- Heterocyclic Compound --- Compound, Heterocyclic --- Compounds, Heterocyclic --- Polycyclic Compounds --- Benzeneacetates --- Benzeneacetic Acids --- Phenylacetic Acids --- Acids, Benzeneacetic --- Acids, Phenylacetic --- Carboxylic Acid --- Acid, Carboxylic --- Acids, Carboxylic --- Behavior Disorders --- Diagnosis, Psychiatric --- Mental Disorders, Severe --- Psychiatric Diagnosis --- Mental Illness --- Psychiatric Diseases --- Psychiatric Disorders --- Psychiatric Illness --- Illness, Mental --- Mental Disorder --- Mental Disorder, Severe --- Mental Illnesses --- Psychiatric Disease --- Psychiatric Disorder --- Psychiatric Illnesses --- Severe Mental Disorder --- Severe Mental Disorders --- Mentally Ill Persons --- Natural Sciences --- Physical Sciences --- Discipline, Natural Science --- Disciplines, Natural Science --- Natural Science --- Natural Science Discipline --- Physical Science --- Science, Natural --- Science, Physical --- Sciences, Natural --- Sciences, Physical --- Carbocyclic Acids --- Child Mental Disorders --- Disorders Usually Diagnosed in Infancy, Childhood or Adolescence --- Child Mental Disorder --- Disorder, Child Mental --- Disorder, Neurodevelopmental --- Disorders, Child Mental --- Disorders, Neurodevelopmental --- Mental Disorder, Child --- Mental Disorders, Child --- Neurodevelopmental Disorder --- Heterocyclic Cpds, 1-Ring --- 1-Ring Heterocyclic Compounds --- 1-Ring Heterocyclic Cpds --- Heterocyclic Compounds, 1 Ring --- Heterocyclic Cpds, 1 Ring --- Therapy --- Treatment --- Therapeutic --- Therapies --- Treatments --- Disease --- Attention Deficit and Disruptive Behavioral Disorders --- Disruptive Behavior Disorder --- Disruptive Behavioral Disorder --- Oppositional Defiant Disorder --- Behavior Disorder, Disruptive --- Behavioral Disorder, Disruptive --- Defiant Disorder, Oppositional --- Disorder, Disruptive Behavioral --- Disruptive Behavioral Disorders --- Problem Behavior --- Biologic Sciences --- Biological Science --- Science, Biological --- Sciences, Biological --- Biological Sciences --- Life Sciences --- Biologic Science --- Biological Science Discipline --- Discipline, Biological Science --- Disciplines, Biological Science --- Life Science --- Science Discipline, Biological --- Science Disciplines, Biological --- Science, Biologic --- Science, Life --- Sciences, Biologic --- Sciences, Life --- Pyridines --- ADDH --- Attention Deficit Disorders with Hyperactivity --- Attention Deficit Hyperactivity Disorders --- Attention Deficit-Hyperactivity Disorder --- Attention Deficit Disorder --- Attention Deficit Hyperactivity Disorder --- Brain Dysfunction, Minimal --- Hyperkinetic Syndrome --- Minimal Brain Dysfunction --- Attention Deficit Disorders --- Attention Deficit-Hyperactivity Disorders --- Deficit Disorder, Attention --- Deficit Disorders, Attention --- Deficit-Hyperactivity Disorder, Attention --- Deficit-Hyperactivity Disorders, Attention --- Disorder, Attention Deficit --- Disorder, Attention Deficit-Hyperactivity --- Disorders, Attention Deficit --- Disorders, Attention Deficit-Hyperactivity --- Dysfunction, Minimal Brain --- Syndromes, Hyperkinetic --- Therapy, Drug --- Pharmacotherapy --- Chemotherapies --- Drug Therapies --- Pharmacotherapies --- Therapies, Drug --- Pharmaceutical Preparations --- Pharmacologic Actions --- Centedrin --- Concerta --- Daytrana --- Equasym --- Metadate --- Methylin --- Methylphenidate Hydrochloride --- Phenidylate --- Ritalin --- Ritalin-SR --- Ritaline --- Tsentedrin --- Hydrochloride, Methylphenidate --- Ritalin SR --- Pharmacologies --- ADD (Child behavior disorder) --- ADHD (Child behavior disorder) --- Attention deficit disorder with hyperactivity --- Attention deficit disorders --- Hyperactive child syndrome --- Hyperkinesia in children --- Hyperkinetic syndrome --- Behavior disorders in children --- Minimal brain dysfunction in children --- Methylphenidate hydrochloride --- Methylphenidylacetate hydrochloride --- Ritalin (Trademark) --- Central nervous system stimulants --- Piperidine --- therapy --- drug therapy --- therapeutic use --- pharmacology --- Attention-deficit hyperactivity disorder. --- Pharmacology. --- Methylphenidate. --- Drug Therapy. --- Attention Deficit Disorder with Hyperactivity. --- Piperidines. --- Biological Science Disciplines. --- Attention Deficit and Disruptive Behavior Disorders. --- Phenylacetates. --- Therapeutics. --- Heterocyclic Compounds, 1-Ring. --- Neurodevelopmental Disorders. --- Acids, Carbocyclic. --- Natural Science Disciplines. --- Mental Disorders. --- Carboxylic Acids. --- Heterocyclic Compounds. --- Organic Chemicals. --- Chemotherapy.

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