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Drugs, sex and a pack of unscrupulous men circling, circling - it was always going to get ugly but no-one foresaw the tragic death of a young woman.
Australians --- Drugs --- Drug overdose --- Overdosage of drugs --- Overdose of drugs --- Poisoning --- Medication errors --- Aussies --- Ethnology --- Overdose. --- Overdosage --- Dosage --- Brimble, Dianne. --- Accidental poisoning --- Trials --- Victims of crimes --- Wrongful death
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"According to the CDC, between 1999 and 2017, more than 700,000 Americans died as a result of drug overdose. In 2017, the number of overdose deaths involving opioids (including prescription opioids and illegal opioids such as heroin and illicitly manufactured fentanyl) was 6 times higher than in 1999. The news is rife with stories surrounding the opioid crisis-from settlements with drug companies, to effective treatment options-even the resistance among museums to accept donations from the Sackler family (which built its fortune on pharmaceutical sales of OxyContin). What was once perceived as a marginal problem has now entered the mainstream, and this book looks at its rise. Nancy Campbell, professor and department head in STS at RPI, traces the history of overdose and overdose prevention. Her research centers on how ideas about drugs and drug addiction have changed over time. She wants to know what we actually know about drug addiction, and how we know it. Why do we have the drug policies that we do? And why do we consider some drugs to cause social problems, and others to solve them. Most importantly, Campbell asks, why did it take tens of thousands of opioid-related overdose deaths annually before a movement rose up to put this technology into the hands of those who needed it most? The book centers around the political contexts within which overdose and overdose prevention became problems that could be solved with a technological fix. As is the case with all such fixes, the social, political, and economic terrain within which they are implemented matter for their success. The book provides an accessible history of how naloxone works in the United States and the United Kingdom, both places that have experienced exponential increases in overdose deaths during the early 21st century (albeit at different scales). As a historical book, it interweaves the story of naloxone's predecessor, nalorphine, with the story of the pharmacological dynamics of the so-called narcotic antagonists. All of the technical terms involved-agonists, antagonists, opioids, and opiates, are clearly defined in the introduction, and in punchy, non-technical prose at that. But it is the story of the protagonists-the people of naloxone-that matters most to Campbell. The protagonists of these social and scientific movements have broadened naloxone access, changing law, medicine, and society-and have saved countless lives. This book, then, traces the story of a single molecule through its multiple social lives, from the enclaves of its past into the wider worlds of its present. We're starting to see a number of books on the market about this epidemic, but what Campbell is doing here is looking specifically at the social movement (the harm reduction movement) aimed at preventing preventable deaths, and the role Naloxone has played in those efforts. Campbell concludes on a powerful note, pointing out that even though we have a technology that can help stop-in-its tracks sudden death, until we start really examining the root causes and circumstances surrounding the rise in opioid abuse and uptake in the first place, this problem is going nowhere"--
Drugs --- Naloxone. --- Overdose. --- Narcotics --- Overdose --- Alkaloids --- Narcotic antagonists --- Drug overdose --- Overdosage of drugs --- Overdose of drugs --- Poisoning --- Medication errors --- Overdosage --- Dosage --- United States --- United Kingdom --- Great Britain --- Isle of Man
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""Grounded equally in solid clinical practice and uniquely relevant research, and tragically leavened by the personal bereavement of two of the book's authors, Devastating Losses sheds new and compassionate light on the experience of a child's death to traumatic causes."". Robert A. Neimeyer , PhD. Editor, Death Studies. ""This volume is a pioneering and long overdue work, a study not only of grieving parents who lost a child to suicide but also of parents whose children succumbed to drug overdoses. The authors have done a masterful job of blending their quantitative research findings and the
Children --- Parents --- Bereavement --- Drugs --- Suicide victims --- Suicides --- Victims of suicide --- Dead --- Victims of crimes --- Drug overdose --- Overdosage of drugs --- Overdose of drugs --- Poisoning --- Medication errors --- Mourning --- Death --- Psychological aspects. --- Psychology. --- Overdose. --- Family relationships. --- Overdosage --- Dosage --- Psychological aspects
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Nonclinical Assessment of Abuse Potential for New Pharmaceuticals offers a complete reference on the current international regulatory guidelines and details best practice methodology for the three standard animal models used to evaluate abuse potential: physical dependence, self-administration and drug discrimination. This book also includes chapters on alternative models and examples of when you should use these alternatives. Case histories are provided at the end of the book to show how the data generated from the animal models play a pivitol role in the submission package for a new drug. By incorporating all of this information into one book, Nonclinical Assessment of Abuse Potential for New Pharmaceuticals is your single resource for everything you need to know to understand and implement the assessment of abuse liability. Provides a consolidated overview of the complex regulatory landscape Offers best practice methodology for conducting animal studies, including selection of doses and positive control agents that will help you improve your own abuse potential studies Includes real-life examples to illustrate how nonclinical data fit into the submission strategy.
Drug abuse. --- Drugs. --- Psychopharmacology. --- Drug Evaluation, Preclinical --- Models, Animal --- Substance-Related Disorders --- Investigative Techniques --- Mental Disorders --- Drug Discovery --- Diseases --- Evaluation Studies as Topic --- Psychiatry and Psychology --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Substance Abuse --- Social Welfare & Social Work --- Social Sciences --- Drugs --- Opioids --- Overdose. --- Opium-like agents --- Analgesics --- Narcotics --- Opium --- Drug overdose --- Overdosage of drugs --- Overdose of drugs --- Poisoning --- Medication errors --- Drug use --- Substance abuse --- Overdosage --- Dosage
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Drug abuse --- Drugs --- Emergency medical services --- Hospitals --- Drug abuse. --- Emergency medical services. --- Substance-Related Disorders --- Emergency Service, Hospital --- Overdose --- Emergency services --- Utilization --- Overdose. --- Utilization. --- epidemiology. --- statistics & numerical data. --- Drug Abuse Warning Network --- Drug Abuse Warning Network. --- United States. --- Benevolent institutions --- Infirmaries --- Health facilities --- Utilization of hospital emergency services --- Hospital utilization --- Emergency health services --- Emergency medical care --- Emergency medicine --- Medical care --- Rescue work --- Drug overdose --- Overdosage of drugs --- Overdose of drugs --- Poisoning --- Medication errors --- Drug use --- Substance abuse --- Medicaments --- Medications --- Medicine (Drugs) --- Medicines (Drugs) --- Pharmaceuticals --- Prescription drugs --- Bioactive compounds --- Medical supplies --- Pharmacopoeias --- Chemotherapy --- Materia medica --- Pharmacology --- Pharmacy --- Emergency service --- Overdosage --- Dosage --- Center for Behavioral Health Statistics and Quality (U.S.). --- DAWN --- National Institute on Drug Abuse. --- Project DAWN --- DAWN (Project) --- ABŞ --- ABSh --- Ameerika Ühendriigid --- America (Republic) --- Amerika Birlăshmish Shtatlary --- Amerika Birlăşmi Ştatları --- Amerika Birlăşmiş Ştatları --- Amerika ka Kelenyalen Jamanaw --- Amerika Qūrama Shtattary --- Amerika Qŭshma Shtatlari --- Amerika Qushma Shtattary --- Amerika (Republic) --- Amerikai Egyesült Államok --- Amerikanʹ Veĭtʹsėndi͡avks Shtattnė --- Amerikări Pĕrleshu̇llĕ Shtatsem --- Amerikas Forenede Stater --- Amerikayi Miatsʻyal Nahangner --- Ameriketako Estatu Batuak --- Amirika Carékat --- AQSh --- Ar. ha-B. --- Arhab --- Artsot ha-Berit --- Artzois Ha'bris --- Bí-kok --- Ē.P.A. --- É.-U. --- EE.UU. --- Egyesült Államok --- ĒPA --- Estados Unidos --- Estados Unidos da América do Norte --- Estados Unidos de América --- Estaos Xuníos --- Estaos Xuníos d'América --- Estatos Unitos --- Estatos Unitos d'America --- Estats Units d'Amèrica --- Ètats-Unis d'Amèrica --- États-Unis d'Amérique --- ÉU --- Fareyniḳṭe Shṭaṭn --- Feriene Steaten --- Feriene Steaten fan Amearika --- Forente stater --- FS --- Hēnomenai Politeiai Amerikēs --- Hēnōmenes Politeies tēs Amerikēs --- Hiwsisayin Amerikayi Miatsʻeal Tērutʻiwnkʻ --- Istadus Unidus --- Jungtinės Amerikos valstybės --- Mei guo --- Mei-kuo --- Meiguo --- Mî-koet --- Miatsʻyal Nahangner --- Miguk --- Na Stàitean Aonaichte --- NSA --- S.U.A. --- SAD --- Saharat ʻAmērikā --- SASht --- Severo-Amerikanskie Shtaty --- Severo-Amerikanskie Soedinennye Shtaty --- Si͡evero-Amerikanskīe Soedinennye Shtaty --- Sjedinjene Američke Države --- Soedinennye Shtaty Ameriki --- Soedinennye Shtaty Severnoĭ Ameriki --- Soedinennye Shtaty Si͡evernoĭ Ameriki --- Spojené obce severoamerické --- Spojené staty americké --- SShA --- Stadoù-Unanet Amerika --- Stáit Aontaithe Mheiriceá --- Stany Zjednoczone --- Stati Uniti --- Stati Uniti d'America --- Stâts Unîts --- Stâts Unîts di Americhe --- Steatyn Unnaneysit --- Steatyn Unnaneysit America --- SUA --- Sŭedineni amerikanski shtati --- Sŭedinenite shtati --- Tetã peteĩ reko Amérikagua --- U.S. --- U.S.A. --- United States of America --- Unol Daleithiau --- Unol Daleithiau America --- Unuiĝintaj Ŝtatoj de Ameriko --- US --- USA --- Usono --- Vaeinigte Staatn --- Vaeinigte Staatn vo Amerika --- Vereinigte Staaten --- Vereinigte Staaten von Amerika --- Verenigde State van Amerika --- Verenigde Staten --- VS --- VSA --- Wááshindoon Bikéyah Ałhidadiidzooígíí --- Wilāyāt al-Muttaḥidah --- Wilāyāt al-Muttaḥidah al-Amirīkīyah --- Wilāyāt al-Muttaḥidah al-Amrīkīyah --- Yhdysvallat --- Yunaeted Stet --- Yunaeted Stet blong Amerika --- ZDA --- Združene države Amerike --- Zʹi͡ednani Derz͡havy Ameryky --- Zjadnośone staty Ameriki --- Zluchanyi͡a Shtaty Ameryki --- Zlucheni Derz͡havy --- ZSA --- Drug Overdose --- Toxicomanie --- Médicaments --- Services des urgences médicales --- Hôpitaux --- Surdosage --- Services des urgences --- Utilisation
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