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The aim of this text is to provide a summary of the present day understanding of diagnosis, management, and best medical and surgical treatment of Marfan syndrome. The authors cover lifelong problems, from birth to old age, in each affected system. Patients may initially be referred to any one of a number of specialists and although each doctor is likely to be familiar with a particular aspect of the syndrome, they are less likely to be familiar with its other features. The fact that the syndrome presents in many different ways may also hinder its recognition. By making this information available, Diagnosis and Management of Marfan Syndrome aims to raise awareness of Marfan syndrome, and to promote best management aimed at prolonging lifespan and improving quality of life. This text has been written by a network of expert physicians who wish to share their hard-won knowledge, and is a useful tool for any clinician likely to encounter a patient with this condition.

Cardiovascular Diseases --- Medicine --- Health & Biological Sciences --- Marfan syndrome --- Diagnosis. --- Treatment. --- Achrochondrohyperplasia --- Arachnodactyly --- Congenital mesodermal dystrophy --- Dolichostenomelia --- Dystrophia mesodermalis congenita --- Hyperchondroplasia --- Marfan-Achard syndrome --- Marfan's syndrome --- Spider fingers (Disease) --- Strebdodactyly --- Connective tissues --- Genetic disorders --- Syndromes --- Diseases --- Cardiology. --- Internal medicine. --- Heart --- Internal Medicine. --- Cardiac Surgery. --- Surgery. --- Cardiac surgery --- Open-heart surgery --- Medicine, Internal --- Internal medicine --- Surgery --- Cardiac surgery.

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Gastrointestinal tract disorders are a wide group of diseases involving both the gastrointestinal tube (esophagus, stomach, small and large intestine) and related organs (liver, pancreas, and gallbladder). These dysfunctions may differ by site, etiology, and severity, going from simple malfunctions to mere diseases. Because of their variety and heterogeneity, gastrointestinal disorders can affect many people and are widespread throughout the population. Therefore, scientific research in this area is facing a great challenge. Better knowledge of gastrointestinal disorders in terms of their pathophysiology, clinical features, and possible complications is necessary for the development of new diagnostic methods and therapeutic strategies. During the last several decades, some scientific developments have already been made, giving more opportunities to these patients. However, much remains to be discovered and to be done to help physicians in their everyday work and to give patients a better prognosis. The present Special Issue aims to highlight recent advances in gastrointestinal tract disorders, focusing on their diagnostic and therapeutic path, evolution, and complications.

Research & information: general --- Chemistry --- Crohn's disease --- ulcerative colitis --- biologics --- anemia --- gastroesophageal reflux --- cough --- asthma --- laryngo-pharyngeal reflux --- chest pain --- tooth erosions --- inflammatory bowel diseases --- sleep disorders --- sleep medicine --- PPI --- diverticulosis --- diverticulitis --- risk factors --- Marfan's syndrome --- diverticula --- abdominal symptoms --- ultrasound --- infant --- food allergy --- fecal biomarkers --- tumor necrosis factor α --- eosinophil derived neurotoxin --- calprotectin --- Emorsan®Gel --- hemorrhoidal disease --- hemorrhoidectomy --- pain --- wound healing --- chronic idiopathic constipation --- constipation --- irritable bowel syndrome --- pathophysiology --- primary care --- medical students --- public health --- social media --- dietary habit --- pandemic --- dyspepsia --- diabetes --- gastroparesis --- inflammatory bowel disease --- SCORE --- carotid plaques --- cardiovascular risk --- dyssynergic defecation --- slow transit constipation --- motility --- colonic transit --- anorectal manometry --- gastrointestinal disorders --- endoscopic vacuum therapy --- etiology --- transmural defect --- upper gastrointestinal tract --- Helicobacter pylori --- eradication --- antibiotic resistance --- tailored --- empirical --- gastrointestinal bleeding --- new oral anticoagulants --- vitamin K antagonist --- rebleeding --- chronic gastritis --- peptic ulcer disease --- gastric cancer --- MALT-lymphoma --- therapy --- vaccines --- DA-9701 --- diabetic mouse model --- functional dyspepsia --- diabetic gastroparesis --- STZ --- gastrointestinal motility --- human leukocyte antigen --- celiac disease --- autoimmune hepatitis --- primary sclerosing cholangitis --- primary biliary cholangitis --- autoimmune pancreatitis --- IgG4-related sclerosing cholangitis --- IgG4-related hepatopathy