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This volume presents recent research achievements concerning the molecular genetic basis of agronomic traits in rice. Rice (Oryza sativa L.) is the most important food crop in the world, being a staple food for more than half of the world’s population. Recent improvements in living standards have increased the worldwide demand for high-yielding and high-quality rice cultivars. To achieve improved agricultural performance in rice, while overcoming the challenges presented by climate change, it is essential to understand the molecular basis of agronomically important traits. Recently developed techniques in molecular biology, especially in genomics and other related omics fields, can reveal the complex molecular mechanisms involved in the control of agronomic traits. As rice was the first crop genome to be sequenced, in 2004, molecular research tools for rice are well-established, and further molecular studies will enable the development of novel rice cultivars with superior agronomic performance.

chloroplast RNA splicing and ribosome maturation (CRM) domain --- intron splicing --- chloroplast development --- rice --- rice (Oryza sativa L.), grain size and weight --- Insertion/Deletion (InDel) markers --- multi-gene allele contributions --- genetic variation --- rice germplasm --- disease resistance --- microbe-associated molecular pattern (MAMP) --- Pyricularia oryzae (formerly Magnaporthe oryzae) --- Oryza sativa (rice) --- receptor-like cytoplasmic kinase (RLCK) --- reactive oxygen species (ROS) --- salinity --- osmotic stress --- combined stress --- GABA --- phenolic metabolism --- CIPKs genes --- shoot apical meristem --- transcriptomic analysis --- co-expression network --- tiller --- nitrogen rate --- rice (Oryza sativa L.) --- quantitative trait locus --- grain protein content --- single nucleotide polymorphism --- residual heterozygote --- rice (Oryza sativa) --- specific length amplified fragment sequencing --- Kjeldahl nitrogen determination --- near infrared reflectance spectroscopy --- heterosis --- yield components --- high-throughput sequence --- FW2.2-like gene --- tiller number --- grain yield --- CRISPR/Cas9 --- genome editing --- off-target effect --- heat stress --- transcriptome --- anther --- anthesis --- pyramiding --- bacterial blight --- marker-assisted selection --- foreground selection --- background selection --- japonica rice --- cold stress --- germinability --- high-density linkage map --- QTLs --- seed dormancy --- ABA --- seed germination --- chromosome segment substitution lines --- linkage mapping --- Oryza sativa L. --- chilling stress --- chlorophyll biosynthesis --- chloroplast biogenesis --- epidermal characteristics --- AAA-ATPase --- salicylic acid --- fatty acid --- Magnaporthe oryzae --- leaf senescence --- quantitative trait loci --- transcriptome analysis --- genetic --- epigenetic --- global methylation --- transgenic --- phenotype --- OsNAR2.1 --- dwarfism --- OsCYP96B4 --- metabolomics --- NMR --- qRT-PCR --- bHLH transcription factor --- lamina joint --- leaf angle --- long grain --- brassinosteroid signaling --- blast disease --- partial resistance --- pi21 --- haplotype --- high night temperature --- wet season --- dry season --- n/a

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Fungal Nanotechnologies (FN) 1 and 2 provide updated and comprehensive information that deals with the green and sustainable production of metal- and organic-based nanostructures by various fungal species. Additionally, intracellular and extracellular mechanisms will be investigated, as well as fungal nanotechnology applications in the biomedical, environmental, and agri-food sectors. FN is still in its infant stage; therefore, many studies should be focused on this area. Plants, animal and humans will benefit greatly from this, and efficient and ecologically friendly approaches should be created.

aflatoxins --- Aspergillus section Flavi --- chitosan --- nanocomposites --- fungal nanotechnology --- Trichoderma spp. --- ZnO nanoparticles --- antibacterial activity Xanthomonas oryzae pv. oryzae --- co-cultivation --- secondary metabolites --- biotransformation --- biomineralization --- metal oxide nanoparticles --- nanoparticle dissolution --- nanoparticle mobility --- fungal leaching --- ecotoxicity --- nanomaterial --- nanosensors --- phytopathogens --- zinc --- endophytic bacteria --- silver nanoparticles --- Magnaporthe oryzae --- antifungal activity --- oyster mushroom --- application --- antibacterial --- anticancer --- antioxidant --- nanohybrids --- polymer-metal composites --- antifungal --- postharvest --- Fusarium --- synthesis --- nanoparticles --- mechanism --- medicine --- agriculture --- nanofactory --- toxicity --- copper (I) iodide --- composites --- atomic force microscopy --- Vicia faba --- plant disease --- root rot --- R. solani --- Se-NPs --- nano-biosynthesis --- plant promotion --- metal oxides --- nano-fungicides --- pathogenic fungi --- protein profiling --- radical scavenging activity --- resistance --- homeostasis --- fungal–metal interaction --- lichen --- green synthesis --- eco-friendly --- antimicrobial --- MgO-NPs --- optimization --- mosquitocidal and repellence activity --- tannery effluents --- chromium ion --- nanoantifungal --- mycotoxin degradation --- theragnostic --- veterinary --- n/a --- bamboo --- Ag/TiO2 --- visible light photoactivity --- energy storage --- fungal-metal interaction

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This volume presents recent research achievements concerning the molecular genetic basis of agronomic traits in rice. Rice (Oryza sativa L.) is the most important food crop in the world, being a staple food for more than half of the world’s population. Recent improvements in living standards have increased the worldwide demand for high-yielding and high-quality rice cultivars. To achieve improved agricultural performance in rice, while overcoming the challenges presented by climate change, it is essential to understand the molecular basis of agronomically important traits. Recently developed techniques in molecular biology, especially in genomics and other related omics fields, can reveal the complex molecular mechanisms involved in the control of agronomic traits. As rice was the first crop genome to be sequenced, in 2004, molecular research tools for rice are well-established, and further molecular studies will enable the development of novel rice cultivars with superior agronomic performance.

Research & information: general --- Biology, life sciences --- Technology, engineering, agriculture --- chloroplast RNA splicing and ribosome maturation (CRM) domain --- intron splicing --- chloroplast development --- rice --- rice (Oryza sativa L.), grain size and weight --- Insertion/Deletion (InDel) markers --- multi-gene allele contributions --- genetic variation --- rice germplasm --- disease resistance --- microbe-associated molecular pattern (MAMP) --- Pyricularia oryzae (formerly Magnaporthe oryzae) --- Oryza sativa (rice) --- receptor-like cytoplasmic kinase (RLCK) --- reactive oxygen species (ROS) --- salinity --- osmotic stress --- combined stress --- GABA --- phenolic metabolism --- CIPKs genes --- shoot apical meristem --- transcriptomic analysis --- co-expression network --- tiller --- nitrogen rate --- rice (Oryza sativa L.) --- quantitative trait locus --- grain protein content --- single nucleotide polymorphism --- residual heterozygote --- rice (Oryza sativa) --- specific length amplified fragment sequencing --- Kjeldahl nitrogen determination --- near infrared reflectance spectroscopy --- heterosis --- yield components --- high-throughput sequence --- FW2.2-like gene --- tiller number --- grain yield --- CRISPR/Cas9 --- genome editing --- off-target effect --- heat stress --- transcriptome --- anther --- anthesis --- pyramiding --- bacterial blight --- marker-assisted selection --- foreground selection --- background selection --- japonica rice --- cold stress --- germinability --- high-density linkage map --- QTLs --- seed dormancy --- ABA --- seed germination --- chromosome segment substitution lines --- linkage mapping --- Oryza sativa L. --- chilling stress --- chlorophyll biosynthesis --- chloroplast biogenesis --- epidermal characteristics --- AAA-ATPase --- salicylic acid --- fatty acid --- Magnaporthe oryzae --- leaf senescence --- quantitative trait loci --- transcriptome analysis --- genetic --- epigenetic --- global methylation --- transgenic --- phenotype --- OsNAR2.1 --- dwarfism --- OsCYP96B4 --- metabolomics --- NMR --- qRT-PCR --- bHLH transcription factor --- lamina joint --- leaf angle --- long grain --- brassinosteroid signaling --- blast disease --- partial resistance --- pi21 --- haplotype --- high night temperature --- wet season --- dry season --- chloroplast RNA splicing and ribosome maturation (CRM) domain --- intron splicing --- chloroplast development --- rice --- rice (Oryza sativa L.), grain size and weight --- Insertion/Deletion (InDel) markers --- multi-gene allele contributions --- genetic variation --- rice germplasm --- disease resistance --- microbe-associated molecular pattern (MAMP) --- Pyricularia oryzae (formerly Magnaporthe oryzae) --- Oryza sativa (rice) --- receptor-like cytoplasmic kinase (RLCK) --- reactive oxygen species (ROS) --- salinity --- osmotic stress --- combined stress --- GABA --- phenolic metabolism --- CIPKs genes --- shoot apical meristem --- transcriptomic analysis --- co-expression network --- tiller --- nitrogen rate --- rice (Oryza sativa L.) --- quantitative trait locus --- grain protein content --- single nucleotide polymorphism --- residual heterozygote --- rice (Oryza sativa) --- specific length amplified fragment sequencing --- Kjeldahl nitrogen determination --- near infrared reflectance spectroscopy --- heterosis --- yield components --- high-throughput sequence --- FW2.2-like gene --- tiller number --- grain yield --- CRISPR/Cas9 --- genome editing --- off-target effect --- heat stress --- transcriptome --- anther --- anthesis --- pyramiding --- bacterial blight --- marker-assisted selection --- foreground selection --- background selection --- japonica rice --- cold stress --- germinability --- high-density linkage map --- QTLs --- seed dormancy --- ABA --- seed germination --- chromosome segment substitution lines --- linkage mapping --- Oryza sativa L. --- chilling stress --- chlorophyll biosynthesis --- chloroplast biogenesis --- epidermal characteristics --- AAA-ATPase --- salicylic acid --- fatty acid --- Magnaporthe oryzae --- leaf senescence --- quantitative trait loci --- transcriptome analysis --- genetic --- epigenetic --- global methylation --- transgenic --- phenotype --- OsNAR2.1 --- dwarfism --- OsCYP96B4 --- metabolomics --- NMR --- qRT-PCR --- bHLH transcription factor --- lamina joint --- leaf angle --- long grain --- brassinosteroid signaling --- blast disease --- partial resistance --- pi21 --- haplotype --- high night temperature --- wet season --- dry season

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A virus (from the Latin word ‘v?rus’ meaning ‘venom’ or ‘poison’) is a microorganism invisible to the naked eye. Viruses can multiply exclusively by entering a cell and using the cell’s resources to create copies of themselves. As the origin of their name suggests, viruses are generally considered dangerous, harmful and often deadly. Some of the most well-studied and widely known viruses, such as HIV and influenza, infect humans. However, viruses can also infect animals, plants and microorganisms, including fungi. Many fungi are medically, ecologically and economically significant, for example, causing diseases to humans, plants and insects or being used in industry to produce bread, cheese, beer and wine. Viruses that infect fungi are called mycoviruses (from the Greek work ‘myco’, meaning ‘fungus’). Mycoviruses do not cause harm to or kill the infected fungus; in contrast, they are ‘friendly’ viruses and we can utilize them to control the growth, pathogenicity and toxin production of fungi. This book describes a range of different mycoviruses and their geographical distribution, transmission and evolution, together with their effects on the fungal hosts and how these are brought about.

n/a --- recombination --- Brunchorstia pinea --- fungal viruses --- virus evolution --- isogenic --- fusarivirus --- Castanea sativa --- sequencing --- PsV-F --- conidiogenesis --- Narnaviridae --- Prunus --- virus discovery --- dicer --- totivirus --- killer toxin --- Saccharomyces paradoxus --- Aspergillus fumigatus tetramycovirus-1. --- Fusarium head blight --- dsRNA --- hypovirus --- killer system --- victorivirus --- Leptosphaeria biglobosa quadrivirus --- Entomophthora --- biological control --- RNA genome --- stone fruit --- hypervirulence --- Aspergillus fumigatus chrysovirus --- phylogeny --- A. fumigatus --- Mymonaviridae --- endornavirus --- mycovirus --- Aspergillus --- double-stranded RNA virus --- gemycircularvirus --- Alphapartitivirus --- Partitivirus --- capsid structure --- RnQV1 --- dsRNA virus --- RNA silencing --- capsid protein --- Rhizoctonia solani AG-1 IA --- multiplex PCR --- A. nidulans --- conifers --- Entomophthoromycotina --- Magnaporthe oryzae. chrysovirus 1 --- sclerogenesis --- Mitovirus --- chrysovirus --- A. niger --- selection pressure --- viral lineage --- A. thermomutatus --- transmission --- Tymovirales --- brown rot --- PcV --- Botrytis cinerea mymonavirus 1 --- Hymenoscyphus pseudoalbidus --- mitovirus --- populations study --- ssRNA --- mitochondrion --- partitivirus --- rice blast fungus --- database mining --- fungal virus --- horizontal virus transmission --- antiviral --- Aspergillus fumigatus partitivirus-1 --- hypovirulence --- Ethiopia --- chestnut blight --- Trichoderma atroviride --- Botrytis cinerea --- Cryphonectria parasitica --- Totiviridae --- small RNA --- infection cushion --- ash dieback --- Beauveria bassiana --- Rhizophagus --- Sclerotinia minor --- polymycovirus --- biocontrol --- genomic structure analysis --- Mycovirus --- dsRNA mycoviruses --- mycorrhizal fungi --- evolution --- invasive species --- transmissibility --- Chalara fraxinea --- tRFs --- ScV-L-A

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Nature continuously produces biologically useful molecules and provides humankind with life-saving drugs or therapies. Natural products (NPs) offer a vast, unique and fascinating chemical diversity and these molecules have evolved for optimal interactions with biological macromolecules. Moreover, natural products feature pharmacologically active pharmacophores which are pharmaceutically validated starting points for the development of new lead compounds. Over half of all approved (from 1981 to 2014) small-molecule drugs derived from NPs, including unaltered NPs, NPs synthetic derivatives and synthetic natural mimics, originated from a NPs pharmacophore or template. According to the FDA, NPs and their derivatives represent over one-third of all FDA-approved new drugs, in particular for anticancer/antibiotic lead compounds, which are remarkably enriched with NPs.

Research & information: general --- Chemistry --- Organic chemistry --- multi-component reaction --- fusidic acid --- TEMPO-conjugate --- electron paramagnetic resonance (EPR) spectroscopy --- caspase-3 --- incomptine A --- sesquiterpene lactone --- Decachaeta incompta --- cytotoxic activity --- iTRAQ --- apoptosis --- ROS production --- violacein --- hepatocellular carcinoma --- proliferation --- stemness --- natural products --- tumor microenvironment (TME) --- lung cancer --- phytochemicals --- botanical agents --- steroidal alkaloids --- solanidane alkaloids --- demissidine --- solanidine --- flavonoids --- coronavirus --- SARS-CoV-2 --- SARS-CoV --- MERS-CoV --- anticancer activity --- apoptosis resistance --- ophiobolin A --- polygodial --- Wittig reaction --- melanoma --- tumor heterogeneity --- pregnancy --- anti-tumor peptides --- in vitro model --- medicinal herbs --- cancer treatment --- cancer stem cells --- drug resistance --- metastasis --- RCE-4 --- PCD --- ATG 4B --- the Bcl-2–Beclin 1 complex --- Sparticola junci --- structure elucidation --- ECD-TDDFT --- COX inhibitory --- molecular docking --- antiproliferative --- cytotoxic --- Sepedonium ampullosporum --- peptaibols --- ampullosporin --- glutamic acid methyl ester --- solid-phase peptide synthesis --- antifungal --- anticancer --- target identification --- kaempferol --- docking --- DARTS --- Src --- breast cancer --- butein --- frondoside-A --- STAT3 --- angiogenesis --- invasion --- viability --- tumor growth --- marine fungi --- Cosmospora sp. --- soudanone --- Magnaporthe oryzae --- co-culture --- phytopathogen --- molecular networking --- metabolomics --- bispecific antibody --- Trypsiligase --- click chemistry --- biorthogonal chemistry --- antibody engineering --- n/a --- the Bcl-2-Beclin 1 complex