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For anyone who treats postmenopausal women, this latest edition of Rogerio Lobo's classic work combines the best from two well-known references: Menopause, and the second edition of Treatment of the Postmenopausal Woman. By adding significant discussions of the basic science behind menopause, it is possible to objectively assess the clinical value and limitations of current approaches to treatment and provide a basis and rationale for strategies that will result in better individualized and specialized care. Not only does the third edition discuss diagnosis and treatment of menop
Menopause --- Complications. --- Hormone therapy. --- Estrogen replacement therapy for menopause --- Hormone replacement therapy for menopause --- Hormone therapy --- Change of life in women --- Female change of life --- Female climacteric --- Climacteric --- Estrogen replacement therapy --- Hormone replacement therapy
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The increasing awareness on the varied consequences of hypogonadism in distinct organs and systems has supported the notion of estrogens as systemic agents. This observation is congruent with the variety of tissues affected by - trogens when used in hormone therapy formulations on hypogonadic women. Apart from the genital tract and the breast, recognized as traditional targets for estrogens, the skeleton, the vascular tree, or the central nervous system, are good examples of territories that have demonstrated sensitivity to estrogens. This evidence has created great interest, as shown by the great amount of lit- ature that has been produced on the bene?ts and risks associated with the use of estrogens. In parallel to the clinical interest, basic research has improved our kno- edge on the complexities involved in estrogen action at the molecular level. Together with effects mediated through speci?c receptors, a concept that has been the mainstay of the interpretation of estrogen action for years, there is enough evidence to hold the notion of receptor-independent effects. The substantial advances in modern technology applied to research have helped in enlightening the particulars of this versatile action of estrogens. This more detailed knowledge on the sophisticated mechanism of action of estrogens has nourished the emergence of multiple hypotheses speculating with the p- sibility of manipulating estrogen action. The notion that a widely extended regulatory system of cell function, as it is the estrogen receptor machinery, might be modulated at wish has arisen as an attractive, although still elusive postulate.
Selective estrogen receptor modulators. --- Menopause --- Estrogen --- Hormone therapy. --- Antagonists. --- Antagonists, Estrogen --- Antiestrogens --- Estrogen antagonists --- Hormone antagonists --- Estrogen replacement therapy for menopause --- Hormone replacement therapy for menopause --- Hormone therapy --- Estrogen receptor modulators, Selective --- SERMs (Drugs) --- Estrogen replacement therapy --- Hormone replacement therapy --- Agonists --- Antagonists --- Gynecology. --- Rheumatology. --- Endocrinology. --- Internal medicine --- Hormones --- Connective tissues --- Joints --- Gynaecology --- Medicine --- Generative organs, Female --- Diseases --- Gynecology . --- Endocrinology .
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This volume presents the evolution of the authors' ideas about estrogen action and its modulation by a new group of drugs called SERMs (Selective Estrogen Receptor Modulators). The pioneering SERMs - tamoxifen and raloxifene - are known to have saved the lives of millions of women around the world and improved the health of millions more. Estrogen is the central hormone of women's health and reproduction. The book is a journey through 40 years of discovery and success in advancing women's health, with the prospect of improved innovation through medicinal chemistry for the future.
Selective estrogen receptor modulators. --- Menopause --- Estrogen --- Women --- Health of women --- Health education of women --- Estrogen replacement therapy --- Estrogen replacement therapy for menopause --- Hormone replacement therapy for menopause --- Hormone therapy --- Estrogen receptor modulators, Selective --- SERMs (Drugs) --- Hormone therapy. --- Therapeutic use. --- Health and hygiene. --- Hygiene --- Diseases --- Hormone replacement therapy --- Agonists --- Antagonists --- Breast --- Receptors. --- Cancer --- Endocrine aspects.
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Removing the shroud of complexity that had engulfed the field of menopause research and management for more than a decade, this unique, case-based resource discusses a range of topics relevant to the reproductive health of the aging female. The opening section includes chapters covering the symptomatology, epidemiology and impact of the menopausal burden, and reviews in depth the most current evidence on the efficacy, risks and benefits of pharmacological and alternative therapies. Utilizing vibrant case material, the second section details common symptoms of menopause and an individualized approach to management, such as sleep loss, skeletal fragility, sexual dysfunction, hirsutism and alopecia, primary ovarian insufficiency and failure, and vasomotor symptoms. Chapters reviewing therapeutic options and considerations tailored to gynecologic and breast cancer patients and survivors comprise the third and final section. Developed as a multidisciplinary collaboration and addressing the needs of practicing reproductive medicine clinicians and researchers providing care to an aging female population, Essentials of Menopause Management provides clear, up-to-date information and recommendations on the range of current treatment strategies for menopause and its symptoms.
Medicine. --- Gynecology. --- Endocrinology. --- Reproductive medicine. --- Medicine & Public Health. --- Reproductive Medicine. --- Menopause --- Hormone therapy. --- Treatment. --- Change of life in women --- Female change of life --- Female climacteric --- Estrogen replacement therapy for menopause --- Hormone replacement therapy for menopause --- Estrogen replacement therapy --- Hormone replacement therapy --- Climacteric --- Hormone therapy --- Internal medicine --- Hormones --- Gynaecology --- Medicine --- Generative organs, Female --- Human reproduction --- Human reproductive health --- Human reproductive medicine --- Reproductive medicine --- Health --- Diseases --- Health aspects --- Gynecology . --- Endocrinology .
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Menopause --- Climacteric --- Menopause. --- Climacteric. --- Hormone Replacement Therapy. --- Sex. --- Women's Health. --- Hormone therapy --- Hormone therapy. --- Estrogen replacement therapy for menopause --- Hormone replacement therapy for menopause --- Change of life in women --- Female change of life --- Female climacteric --- Change of life --- Woman's Health --- Womens Health --- Health, Woman's --- Health, Women's --- Health, Womens --- Genotypic Sex --- Phenotypic Sex --- Sex, Genotypic --- Sex, Phenotypic --- Therapy, Hormone Replacement --- Replacement Therapy, Hormone --- Hormone Replacement Therapies --- Replacement Therapies, Hormone --- Therapies, Hormone Replacement --- Change of Life --- Climacterics --- Life Change --- Life Changes --- Change of Life, Female --- Estrogen replacement therapy --- Hormone replacement therapy --- Middle age --- Physiology --- Sexual Behavior --- Sex Characteristics --- Sex Determination Analysis
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When it comes to any current scientific debate, there are more than two sides to every story. 'Controversies in Science and Technology' analyzes controversial topics in science and technology - infrastructure, ecosystem management, food security and plastics and health - from multiple points of view.
Science and civilization. --- Genetic engineering. --- Antibiotics in animal nutrition. --- Menopause --- Bioterrorism. --- Science --- Technology --- Bio-terrorism --- Biological terrorism --- Bioterrorism --- Terrorism --- Estrogen replacement therapy for menopause --- Hormone replacement therapy for menopause --- Hormone therapy --- Antibiotics in agriculture --- Antibiotics in nutrition --- Medicated feeds --- Designed genetic change --- Engineering, Genetic --- Gene splicing --- Genetic intervention --- Genetic surgery --- Genetic recombination --- Biotechnology --- Transgenic organisms --- Civilization and science --- History and science --- Science and history --- Science and society --- Progress --- Sociology of science --- Hormone therapy. --- Social aspects. --- Law and legislation --- Estrogen replacement therapy --- Hormone replacement therapy --- Sustainable development. --- Development, Sustainable --- Ecologically sustainable development --- Economic development, Sustainable --- Economic sustainability --- ESD (Ecologically sustainable development) --- Smart growth --- Sustainable development --- Sustainable economic development --- Economic development --- Environmental aspects
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The decision-making process that underlies ovarian hormone therapy (HT) is a fallible one. The question is whether or not physicians should prescribe HT to menopausal women, who are at a time in their lives when they are factoring various concerns into their decision to take (or not take) HT. Not only is it difficult to determine whether or not to prescribe HT, but what kind; should physicians recommend estrogen or progestin, or another combination of related hormones? The decision of whether or not to use HT has affected, and will continue to affect, many women in the United States and throughout the world and is an important model elucidating the forces that influence medical decision-making. Two recent large-scale studies, one conducted here in the United States (the Women’s Health Initiative) and the other in Great Britain (the Million Women Study), were highly publicized and cast a negative light on the use of HT. Since HT’s inception, views have oscillated, due in part to expectations of benefits extending over the course of long-term use beyond the peri-menopausal period, and perhaps due to the overselling of research investigating the efficacy of HT. Thus, the decision for women to go on HT remains a controversial issue, and the decision-making process is undermined further by overzealous advertising and an exaggerated understanding of the research results (both positive and negative). This book is unique in that it integrates core findings from within the Decision Sciences and Evidence Based Medicine in light of the research that has been done on HT. Medical Decisions, Estrogen and Aging integrates the various components that go into medical decision making in the context of understanding the dilemmas that surround HT. Therefore this book is intended for both specialists and generalists in the field, and it is ideally suited for use by graduate and medical students, medical health care professionals, behavioral scientists, medical ethicists, gerontologists, historians of science, and endocrinologists.
Menopause --- Middle-aged women --- Hormone therapy. --- Health and hygiene. --- Estrogen replacement therapy for menopause --- Hormone replacement therapy for menopause --- Hormone therapy --- Estrogen replacement therapy --- Hormone replacement therapy --- Medicine. --- Aging --- Quality of Life --- Medical Education. --- Medicine-Philosophy. --- Biomedicine general. --- Aging. --- Quality of Life Research. --- Philosophy of Medicine. --- Research. --- Medical personnel --- Professional education --- Life, Quality of --- Economic history --- Human ecology --- Life --- Social history --- Basic needs --- Human comfort --- Social accounting --- Work-life balance --- Age --- Ageing --- Senescence --- Developmental biology --- Gerontology --- Longevity --- Age factors in disease --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Medical sciences --- Pathology --- Physicians --- Education --- Physiological effect --- Medicine --- Philosophy. --- Medical logic --- Medical research. --- Medical education. --- Medicine—Philosophy. --- Biomedicine, general. --- Health Workforce --- Biomedical research --- Medical research
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Menopause --- Estrogen Replacement Therapy --- Hormone therapy --- Menopause. --- Estrogen Replacement Therapy. --- Gynecology. --- Societies, Medical. --- Hormone therapy. --- Estrogen Progestin Combination Therapy --- Estrogen Progestin Replacement Therapy --- Estrogen Replacement --- Replacement, Estrogen --- Therapy, Estrogen Replacement --- Hormone Replacement Therapy, Post-Menopausal --- Postmenopausal Hormone Replacement Therapy --- Replacement Therapy, Estrogen --- Estrogen Replacement Therapies --- Estrogen Replacements --- Hormone Replacement Therapy, Post Menopausal --- Replacement Therapies, Estrogen --- Replacements, Estrogen --- Therapies, Estrogen Replacement --- Change of Life, Female --- Change of life in women --- Female change of life --- Female climacteric --- Estrogen replacement therapy for menopause --- Hormone replacement therapy for menopause --- Medical Societies --- Medical Society --- Society, Medical --- Estrogen replacement therapy --- Hormone replacement therapy --- Gynecologic Surgical Procedures --- Climacteric --- Gynecology --- Societies, Medical --- Health Sciences --- Medical Education, Training & Research --- Obstetrics and Gynecology --- Oncology --- Reproduction & Reproductive Medicine --- Menopausa --- Menopausa.
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Testosterone has inspired dreams-of restored youth, recharged sexual appetites, faster running, quicker thinking, bigger muscles-since it was first synthesized in 1935. This provocative book investigates the complex, bizarre, and sometimes outrageous history of synthetic testosterone and other male hormone therapies. Exploring many little-known social arenas-both inside and outside the medical world-in which these substances are becoming increasingly available and accepted, Testosterone Dreams examines the implications and dangers of their use in professional sports, in the workplace, in our sex lives, and beyond. Testosterone Dreams tells the story of testosterone's growing and sometimes concealed influence in our culture over the past 70 years. It explores such controversial topics as the invention and marketing of the male menopause, the disturbing history of hormonal and other medical treatments aimed at boosting or suppressing women's sexuality, and hormone doping in sporting events such as the Tour de France and the Olympics, and in Major League Baseball. It brings to light the hidden use of hormone doping by policemen, soldiers, and other workers in a variety of jobs. It also discusses the burgeoning steroid use in the gay community and its relation to AIDS, and takes a hard look at the pharmaceutical industry's promotional campaigns to create new markets for testosterone products. Testosterone Dreams is the first book to bring together the whole story of testosterone and to consider its social and ethical implications: Where does therapy end and performance enhancement begin? How are changing medical technologies affecting how we think about our identities as men and women and the elusive goal of "well-being"? This book will be essential reading as we move inexorably toward the wide-open, libertarian pharmacology that is now making these drug regimes available to a wider and wider clientele.
Testosterone. --- Hormone therapy. --- Menopause --- Testosterone --- Longevity. --- Aphrodisiacs. --- Love philters --- Love philtres --- Love potions --- Philters --- Philtres --- Drugs --- Life, Long --- Life extension --- Life span prolongation --- Long life --- Prolongation of life span --- Age --- Health --- Life spans (Biology) --- Old age --- Androgens --- Estrogen replacement therapy for menopause --- Hormone replacement therapy for menopause --- Hormone therapy --- Endocrine therapy --- Hormones --- Therapeutics --- Therapeutic use. --- Physiological effect. --- Estrogen replacement therapy --- Hormone replacement therapy --- Therapeutic use --- Aphrodisiacs --- Longevity --- 613.83 --- 796.011.5 --- 796.011.5 Ethiek van de sport. Fair play --- Ethiek van de sport. Fair play --- 613.83 Narcotics --- Narcotics --- Physiological effect --- 20th century. --- aids. --- aphrodisia. --- athletes. --- controversial topic. --- ethics of testosterone use. --- hormone dipping. --- hormone doping. --- hormone therapy. --- hormone treatments. --- male hormones. --- masculinity. --- medical community. --- medical technologies. --- medical treatments. --- men and women. --- muscle building. --- pharmacology. --- professional sports. --- scientists. --- sexual appetites. --- sexuality. --- social perspective. --- social sciences. --- soldiers. --- steroid use. --- synthetic testosterone. --- testosterone.
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