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Modern Menopausal Hormone Treatment
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ISBN: 9783030927356 Year: 2022 Publisher: Cham Springer International Publishing :Imprint: Springer

Treatment of the postmenopausal woman : basic and clinical aspects
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ISBN: 128104962X 9786611049621 0080553095 0123694434 Year: 2007 Publisher: Burlington, MA : Academic Press/Elsevier,

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For anyone who treats postmenopausal women, this latest edition of Rogerio Lobo's classic work combines the best from two well-known references: Menopause, and the second edition of Treatment of the Postmenopausal Woman. By adding significant discussions of the basic science behind menopause, it is possible to objectively assess the clinical value and limitations of current approaches to treatment and provide a basis and rationale for strategies that will result in better individualized and specialized care. Not only does the third edition discuss diagnosis and treatment of menop

Selective estrogen receptor modulators : a new brand of multitarget drugs
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ISBN: 1280716649 9786610716647 3540347429 3540242279 3642445527 Year: 2006 Publisher: Berlin ; New York : Springer,

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The increasing awareness on the varied consequences of hypogonadism in distinct organs and systems has supported the notion of estrogens as systemic agents. This observation is congruent with the variety of tissues affected by - trogens when used in hormone therapy formulations on hypogonadic women. Apart from the genital tract and the breast, recognized as traditional targets for estrogens, the skeleton, the vascular tree, or the central nervous system, are good examples of territories that have demonstrated sensitivity to estrogens. This evidence has created great interest, as shown by the great amount of lit- ature that has been produced on the bene?ts and risks associated with the use of estrogens. In parallel to the clinical interest, basic research has improved our kno- edge on the complexities involved in estrogen action at the molecular level. Together with effects mediated through speci?c receptors, a concept that has been the mainstay of the interpretation of estrogen action for years, there is enough evidence to hold the notion of receptor-independent effects. The substantial advances in modern technology applied to research have helped in enlightening the particulars of this versatile action of estrogens. This more detailed knowledge on the sophisticated mechanism of action of estrogens has nourished the emergence of multiple hypotheses speculating with the p- sibility of manipulating estrogen action. The notion that a widely extended regulatory system of cell function, as it is the estrogen receptor machinery, might be modulated at wish has arisen as an attractive, although still elusive postulate.


Book
Estrogen action, selective estrogen receptor modulators, and women's health
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ISBN: 1848169582 9781848169586 1299713645 9781299713642 Year: 2013 Publisher: London Imperial College Press

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This volume presents the evolution of the authors' ideas about estrogen action and its modulation by a new group of drugs called SERMs (Selective Estrogen Receptor Modulators). The pioneering SERMs - tamoxifen and raloxifene - are known to have saved the lives of millions of women around the world and improved the health of millions more. Estrogen is the central hormone of women's health and reproduction. The book is a journey through 40 years of discovery and success in advancing women's health, with the prospect of improved innovation through medicinal chemistry for the future.


Book
Essentials of Menopause Management : A Case-Based Approach
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ISBN: 3319424513 3319424491 Year: 2017 Publisher: Cham : Springer International Publishing : Imprint: Springer,

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Removing the shroud of complexity that had engulfed the field of menopause research and management for more than a decade, this unique, case-based resource discusses a range of topics relevant to the reproductive health of the aging female. The opening section includes chapters covering the symptomatology, epidemiology and impact of the menopausal burden, and reviews in depth the most current evidence on the efficacy, risks and benefits of pharmacological and alternative therapies. Utilizing vibrant case material, the second section details common symptoms of menopause and an individualized approach to management, such as sleep loss, skeletal fragility, sexual dysfunction, hirsutism and alopecia, primary ovarian insufficiency and failure, and vasomotor symptoms. Chapters reviewing therapeutic options and considerations tailored to gynecologic and breast cancer patients and survivors comprise the third and final section. Developed as a multidisciplinary collaboration and addressing the needs of practicing reproductive medicine clinicians and researchers providing care to an aging female population, Essentials of Menopause Management provides clear, up-to-date information and recommendations on the range of current treatment strategies for menopause and its symptoms.


Book
Controversies in science & technology.
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ISBN: 0197562973 0199383782 9780199383788 9780199383771 Year: 2014 Publisher: Oxford

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When it comes to any current scientific debate, there are more than two sides to every story. 'Controversies in Science and Technology' analyzes controversial topics in science and technology - infrastructure, ecosystem management, food security and plastics and health - from multiple points of view.


Book
Medical decisions, estrogen and aging
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ISBN: 1281141062 9786611141066 1402066864 Year: 2008 Publisher: [Berlin] : Springer,

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The decision-making process that underlies ovarian hormone therapy (HT) is a fallible one. The question is whether or not physicians should prescribe HT to menopausal women, who are at a time in their lives when they are factoring various concerns into their decision to take (or not take) HT. Not only is it difficult to determine whether or not to prescribe HT, but what kind; should physicians recommend estrogen or progestin, or another combination of related hormones? The decision of whether or not to use HT has affected, and will continue to affect, many women in the United States and throughout the world and is an important model elucidating the forces that influence medical decision-making. Two recent large-scale studies, one conducted here in the United States (the Women’s Health Initiative) and the other in Great Britain (the Million Women Study), were highly publicized and cast a negative light on the use of HT. Since HT’s inception, views have oscillated, due in part to expectations of benefits extending over the course of long-term use beyond the peri-menopausal period, and perhaps due to the overselling of research investigating the efficacy of HT. Thus, the decision for women to go on HT remains a controversial issue, and the decision-making process is undermined further by overzealous advertising and an exaggerated understanding of the research results (both positive and negative). This book is unique in that it integrates core findings from within the Decision Sciences and Evidence Based Medicine in light of the research that has been done on HT. Medical Decisions, Estrogen and Aging integrates the various components that go into medical decision making in the context of understanding the dilemmas that surround HT. Therefore this book is intended for both specialists and generalists in the field, and it is ideally suited for use by graduate and medical students, medical health care professionals, behavioral scientists, medical ethicists, gerontologists, historians of science, and endocrinologists.


Periodical
Climacteric : the journal of the International Menopause Society.
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ISSN: 14730804 13697137 Year: 1998 Publisher: [New York] : [Parthenon Pub.]

Testosterone dreams
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ISBN: 1282358502 9786612358500 0520939786 1597349356 9780520939783 9781597349352 1417573961 9781417573967 0520221516 9781282358508 0520248228 9780520248229 6612358505 Year: 2005 Publisher: Berkeley University of California Press

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Testosterone has inspired dreams-of restored youth, recharged sexual appetites, faster running, quicker thinking, bigger muscles-since it was first synthesized in 1935. This provocative book investigates the complex, bizarre, and sometimes outrageous history of synthetic testosterone and other male hormone therapies. Exploring many little-known social arenas-both inside and outside the medical world-in which these substances are becoming increasingly available and accepted, Testosterone Dreams examines the implications and dangers of their use in professional sports, in the workplace, in our sex lives, and beyond. Testosterone Dreams tells the story of testosterone's growing and sometimes concealed influence in our culture over the past 70 years. It explores such controversial topics as the invention and marketing of the male menopause, the disturbing history of hormonal and other medical treatments aimed at boosting or suppressing women's sexuality, and hormone doping in sporting events such as the Tour de France and the Olympics, and in Major League Baseball. It brings to light the hidden use of hormone doping by policemen, soldiers, and other workers in a variety of jobs. It also discusses the burgeoning steroid use in the gay community and its relation to AIDS, and takes a hard look at the pharmaceutical industry's promotional campaigns to create new markets for testosterone products. Testosterone Dreams is the first book to bring together the whole story of testosterone and to consider its social and ethical implications: Where does therapy end and performance enhancement begin? How are changing medical technologies affecting how we think about our identities as men and women and the elusive goal of "well-being"? This book will be essential reading as we move inexorably toward the wide-open, libertarian pharmacology that is now making these drug regimes available to a wider and wider clientele.

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