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This book incorporates a multi-disciplinary approach to present how research results can be translated into clinical trials. The first part begins with a chapter on variants of pancreatic cancer, precursor lesions and groups of people at risk to developing the disease. There is a particular focus on intraductal papillary mucinous neoplasia as a large-scale clinical challenge in pancreatology. The next two parts focus on diagnosis, biomarkers and stratification that emphasize how various approaches to biomarker development are important as both prognostic and predictive tools. The final part consists of personalized treatment approaches that include preclinical models of pancreatic cancer and stromal, epigenetic and metabolism targeting as promising approaches to be translated into early phase clinical trials. Chapters within this part also deal with approaches that are close to being implemented in clinical practice or are already being tested in (early) clinical trials, such as those that targeting the immune systems and strategies to overcome immunotherapy resistance; phase 1 clinical trials and translational approaches in surgical treatment. Written by experts in their fields, Translational Pancreatic Cancer Research provides an outlook towards future directions by integrating information both from basic and clinical research and though demonstrating pathways to better understanding pancreatic cancer and current approaches to translating these into clinical practice.

Oncology  . --- Pathology. --- Oncology. --- Disease (Pathology) --- Medical sciences --- Diseases --- Medicine --- Medicine, Preventive --- Tumors --- Pancreas --- Cancer --- Research. --- Càncer de pàncrees --- Cirurgia oncològica --- Cirurgia del càncer --- Extirpació del càncer --- Oncologia quirúrgica --- Cirurgia --- Càncer

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This book covers all essential evidence on perioperative care and anesthetic concerns for cancer surgeries, including the evaluation and assessment of patients’ schedule for cancer surgeries, perioperative anesthetic management of various cancers, perioperative analgesia for cancer surgeries, and issues related to inoperable cancers. It reviews anesthetic considerations of all cancer types as there is a wide variation in anesthetic requirements in this subset of patients. Cancer surgeries are on the rise worldwide and healthcare facilities with cancer as a core specialty are emerging quickly around the globe. As cancer is on rise and efficient surgical management is available, more and more patients are being treated surgically. However, cancer surgeries are complicated, have varied concerns and these are not covered sufficiently in presently available textbooks of anesthesiology. This book fulfills the growing need for complete and comprehensive textbook of onco-anesthesia and fills the gap in the current texts that do not exclusively cover anesthesia for cancer surgeries. This textbook serves as a comprehensive but quick guide for trainee residents/fellows and practicing anesthesiologists, clinicians and surgeons.

Anesthesiology. --- Palliative treatment. --- Oncology  . --- Palliative Medicine. --- Oncology. --- Tumors --- Palliation (Medical care) --- Palliative care --- Palliative medicine --- Therapeutics --- Anaesthesiology --- Surgery --- Anestesiologia --- Cirurgia oncològica --- Cirurgia del càncer --- Extirpació del càncer --- Oncologia quirúrgica --- Cirurgia --- Càncer --- Anestèsia --- Dolor

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This book provides an up-to-date and comprehensive primer on image-guided interventions for cancer. Image-guided interventional oncology is gaining popularity as it is a minimally invasive and more precisely targeted approach that both proves more effective and results in fewer side effects. This book’s aim is to provide a clinical guide to interventional oncology for the entire oncology team. Chapters are approached with the same interdisciplinary perspective that is used in the care itself, with each chapter written by an interventional radiologist with contributions from medical, surgical and/or radiation oncologists. Chapters cover the major cancers that can benefit from interventional oncology treatment (including lung, liver, kidney, and bone), as well as some of the physics and physiology behind these interventional modalities. This is an ideal guide for interventional radiologists, medical oncologists, surgical oncologists, radiation oncologists, as well as relevant trainees. .

Interventional radiology . --- Oncology  . --- Interventional Radiology. --- Oncology. --- Tumors --- Radiology, Interventional --- Medical radiology --- Therapeutics --- Interventional radiology. --- Radiotherapy. --- Neoplasms --- Tumours --- Pathology --- Cysts (Pathology) --- Oncology --- Cirurgia oncològica --- Imatges mèdiques --- Imatges en medicina --- Sistemes d'imatges en medicina --- Tècniques d'imatge en medicina --- Aparells i instruments mèdics --- Sistemes d'imatges --- Diagnòstic per la imatge --- Fotografia mèdica --- Radiografia mèdica --- Cirurgia del càncer --- Extirpació del càncer --- Oncologia quirúrgica --- Cirurgia --- Càncer

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This book provides surgeons and oncologists with a well-founded and detailed overview of the available treatment options for peritoneal malignancy and differential selection of the appropriate forms of therapy. Systemic chemotherapy options are also considered, as are surgical cytoreduction (CRS) and all forms of intraperitoneal chemotherapy (IPC) especially hyperthermic IPC (HIPEC), and immunotherapy, including specific procedures such as PIPAC. Subsequent chapters address perioperative care, complications and recurrences, as well as psycho-oncological, palliative medical and nursing care. The process of parietal and visceral peritonectomy in the large and small intestine is additionally illustrated by three video clips accessible online. Covering a broad range of aspects, including peritoneal metastasis and intraperitoneal chemotherapy, the book offers a valuable tool for surgeons, oncologists and anesthesiologists alike.

Surgery. --- Oncology  . --- Anesthesiology. --- Rehabilitation medicine. --- Oncology. --- Rehabilitation Medicine. --- Medicine, Rehabilitation --- Rehabilitation medicine --- Rehabilitation --- Medicine, Physical --- Anaesthesiology --- Surgery --- Tumors --- Surgery, Primitive --- Medicine --- Cirurgia oncològica --- Tumors de parts toves --- Metàstas --- Peritoneu --- Abdomen --- Membranes (Biologia) --- Neoplasmes dels teixits tous --- Tumors de teixits tous --- Tumors dels teixits tous --- Cirurgia del càncer --- Extirpació del càncer --- Oncologia quirúrgica --- Cirurgia --- Càncer --- Metàstasi

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This book introduces the current state of surgical treatment in this particular location-sacrum and pelvis, presenting progress and innovation, describing in detail the related procedures. The book comprises three main parts, pelvic, sacral and typical cases. In each part, chapters are organized in a parallel fashion, with general considerations, surgical approaches and commonly used procedures. This helps to illustrate and detail the surgical techniques involved. This book is valuable for surgeons dealing with this challenging disease. Additionally, it summarizes and reinforces the previous knowledge of techniques in this field.

Pelvis --- Sacrum --- Pelvic Neoplasms --- Tumors --- Surgery. --- Os sacrum --- Sacral bone --- Sacral vertebrae --- Sacrococcygeal region --- Vertebrae --- Pelvic cavity --- Pelvic region --- Anatomy --- Orthopedics. --- Surgical oncology. --- Surgical Orthopedics. --- Surgical Oncology. --- Cancer --- Oncologic surgery --- Oncological surgery --- Surgical oncology --- Orthopaedics --- Orthopedia --- Surgery --- Excision --- Treatment --- Cirurgia ortopèdica --- Cirurgia oncològica --- Articulació sacroilíaca --- Articulacions --- Cirurgia del càncer --- Extirpació del càncer --- Oncologia quirúrgica --- Cirurgia --- Càncer --- Cirurgia de l'aparell locomotor --- Ortopèdia --- Artroplàstia --- Cirurgia dels ossos --- Pròtesis ortopèdiques --- Traumatologia