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Medicine has coined the concept of 'disease', but individual patients frequently present complicated cases marked by the coexistence of several conditions or syndromes. The doctor needs to reflect on this complexity because, in his daily practice, he has to address and resolve it for a correct management of the patient. This is why we must, with genuine humility, seek to share a journey in which there are no major landmarks. The authority of the various colleagues who have contributed the different chapters can offer elements of guidance that are useful in a series based on the leitmotif of the cornerstone concepts of complexity. My thanks to those who have accepted this challenge, in the sincere hope that it may enrich us – even just a little and by slow degrees – with an enhanced capacity to address the daily issue of the complexity of the sick.
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Cette édition numérique a été réalisée à partir d'un support physique, parfois ancien, conservé au sein du dépôt légal de la Bibliothèque nationale de France, conformément à la loi n° 2012-287 du 1er mars 2012 relative à l'exploitation des Livres indisponibles du XXe siècle.
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Medicine has coined the concept of 'disease', but individual patients frequently present complicated cases marked by the coexistence of several conditions or syndromes. The doctor needs to reflect on this complexity because, in his daily practice, he has to address and resolve it for a correct management of the patient. This is why we must, with genuine humility, seek to share a journey in which there are no major landmarks. The authority of the various colleagues who have contributed the different chapters can offer elements of guidance that are useful in a series based on the leitmotif of the cornerstone concepts of complexity. My thanks to those who have accepted this challenge, in the sincere hope that it may enrich us – even just a little and by slow degrees – with an enhanced capacity to address the daily issue of the complexity of the sick.
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Medicine has coined the concept of 'disease', but individual patients frequently present complicated cases marked by the coexistence of several conditions or syndromes. The doctor needs to reflect on this complexity because, in his daily practice, he has to address and resolve it for a correct management of the patient. This is why we must, with genuine humility, seek to share a journey in which there are no major landmarks. The authority of the various colleagues who have contributed the different chapters can offer elements of guidance that are useful in a series based on the leitmotif of the cornerstone concepts of complexity. My thanks to those who have accepted this challenge, in the sincere hope that it may enrich us – even just a little and by slow degrees – with an enhanced capacity to address the daily issue of the complexity of the sick.
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This dissertation by Albert Duvetorp explores the complex interplay of comorbidity, comedication, and disease biomarkers in psoriasis, an inflammatory skin disease. The work is grounded in research conducted at Linköping University and aims to address the broader impacts of psoriasis beyond skin symptoms, advocating for a holistic approach to treatment. Key studies within the dissertation investigate the potential of serum calprotectin as a biomarker and examine the effects of narrowband UVB treatment on psoriasis. The research highlights the importance of understanding comorbid conditions and aims to promote integrated care strategies. This work primarily targets medical professionals and researchers interested in dermatology and systemic disease management.
Psoriasis. --- Comorbidity. --- Psoriasis --- Comorbidity
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This dissertation explores the complex interactions between stress, comorbidities, and fatigue in patients with Irritable Bowel Syndrome (IBS). The research aims to deepen understanding of IBS, a disorder characterized by altered gut-brain interactions. It highlights the role of stress and immune activation in IBS pathology, examining factors like hair cortisol levels and self-rated health. The study utilizes data from IBS patients in primary and secondary care settings, comparing them with control groups to assess stress responses and healthcare utilization. The findings suggest IBS patients often experience higher stress and fatigue, with comorbid sleep disorders significantly impacting healthcare usage. The research emphasizes the need for targeted interventions to improve patient outcomes, particularly in addressing fatigue and enhancing patients' sense of coherence. This work is intended for healthcare professionals and researchers interested in the psychosocial aspects of chronic gastrointestinal disorders.
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This publication by the World Health Organization provides a comprehensive framework for addressing tuberculosis (TB) alongside its comorbidities. It aims to enhance collaborative action through governance strengthening, service quality analysis, resource mobilization, and the scaling up of TB-related healthcare services. The document outlines key drivers and risk factors of the TB epidemic, emphasizing the importance of coordinated planning and resource allocation. It includes principles, goals, and objectives for global TB programs, and it is intended for stakeholders involved in TB management and public health policy. The framework serves as a guideline for implementing effective TB care, monitoring, evaluation, and research, while targeting a global audience of health professionals, policymakers, and organizations involved in TB prevention and treatment.
Tuberculosis. --- Comorbidity. --- Tuberculosis --- Comorbidity
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Whilst the vast majority of headaches are minor ailments, some patients develop chronic symptoms that have psychiatric dimensions. These symptoms can be immensely challenging to manage and can have a serious impact on the patient's quality of life. The relationship between headache and psychiatric disease is often rationalized as cause and effect; however, the interplay between the two is complex. Management of each of the co-morbid disorders affects the other one in positive and/or negative ways. The Neuropsychiatry of Headache details the current concepts of various headache conditions and the psychiatric syndromes; topics covered include migraine, mood disorders, medication overuse and personality disorders. Headache specialists, neurologists, psychiatrists, neuropsychiatrists and neuropsychologists will find this an invaluable resource for understanding and co-managing these conditions.
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Comorbidity. --- Substance abuse --- Treatment.
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