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Chemotactic Factors --- Cytokines --- Dermatitis --- Interleukin-8 --- Psoriasis --- Skin --- physiology --- immunology
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Chemokines --- Congresses --- Chemokines - Congresses. --- Chemotactic factors --- Chemotaxis, leukocyte --- Cytokines --- Inflammation --- Interleukin-8
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Chemotaxis, Leukocyte --- Cytokines --- Cell Adhesion --- Receptors, Interleukin --- Chemotactic Factors --- immunology --- physiology --- biosynthesis
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Animal psychology and neurophysiology --- Feromonen --- Pheromones --- Pheromomes --- Chemoreceptor Cells --- Pheromones. --- 577.19 --- Hormones --- Semiochemicals --- Sex recognition (Zoology) --- Synomones --- Allelochemicals --- Allomones --- Ectohormones --- Kairomones --- Animal Communication --- Chemotactic Factors --- Pheromones and phytocins --- Internal medicine --- Physiology. --- Endocrinology --- Endocrinology. --- 577.19 Pheromones and phytocins --- Allelochemical --- Allomone --- Kairomone --- Pheromone --- Semiochemical
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Environmental chemistry --- Chemistry --- Ecology --- Pheromones --- Chemical ecology --- Chimie de l'environnement --- Chimie --- Écologie --- Phéromones --- Synomones --- Allelochemicals --- Allomones --- Ectohormones --- Kairomones --- Semiochemicals --- Chemoecology --- Animal Communication --- Chemotactic Factors --- Metabolites --- Chemosensory ecology --- Allelochemical --- Allomone --- Kairomone --- Pheromone --- Semiochemical --- Chemistry. --- Ecology. --- Pheromones. --- Bionomics --- Ecologies --- Environmental Psychology --- Conservation of Natural Resources --- Environmental Health --- Ecosystem --- Écologie chimique --- Chimie. --- Phéromones.
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Animal psychology and neurophysiology --- Mammals --- Smell --- Odors --- Pheromones --- Mammifères --- Odorat --- Odeurs --- Phéromones --- Physiology --- Behavior --- Physiologie --- Moeurs et comportement --- Behavior, Animal. --- Mammals. --- Odors. --- Pheromones. --- -Mammals --- -Odors. --- 591.185.34 --- 591.572.4 --- 591.58 --- Olfaction --- Chemical senses --- Senses and sensation --- Nose --- Hormones --- Semiochemicals --- Sex recognition (Zoology) --- Aromas --- Fragrances --- Scents --- Smells --- Sensory evaluation --- Eutheria --- Mammalia --- Mammalians --- Prototheria --- Theria --- Vertebrates --- Synomones --- Allelochemicals --- Allomones --- Ectohormones --- Kairomones --- Animal Communication --- Chemotactic Factors --- Odor --- Mammal --- Animal Behavior --- Animal Behaviors --- Behaviors, Animal --- Ethology --- Sense of smell (olfaction) --- Mucus and wax secretion --- Communication and expression by sound or ultrasonic vibrations, mime or other signals, smell, touch or chemical sense (chemoreception) --- Animal communication. --- Smell. --- Physiology. --- Odorants. --- Odorant --- Behavior. --- 591.58 Communication and expression by sound or ultrasonic vibrations, mime or other signals, smell, touch or chemical sense (chemoreception) --- 591.572.4 Mucus and wax secretion --- 591.185.34 Sense of smell (olfaction) --- Mammifères --- Phéromones --- Behavior, Animal --- Odorants --- Aroma --- Fragrance --- Scent --- Odours --- Allelochemical --- Allomone --- Kairomone --- Pheromone --- Semiochemical --- Autotomy Animal --- Mammalian physiology --- Mammals - Physiology --- Mammals - Behavior
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Medicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art of medicinal chemistry continues to challenge its practitioners with the need for both intuition and experience to discover new drugs. Hence sharing the experience of drug research is uniquely beneficial to the field of medicinal chemistry. Drug research requires interdisciplinary team-work at the interface between chemistry, biology and medicine. Therefore, the topic-related series Topics in Medicinal Chemistry covers all relevant aspects of drug research, e.g. pathobiochemistry of diseases, identification and validation of (emerging) drug targets, structural biology, drugability of targets, drug design approaches, chemogenomics, synthetic chemistry including combinatorial methods, bioorganic chemistry, natural compounds, high-throughput screening, pharmacological in vitro and in vivo investigations, drug-receptor interactions on the molecular level, structure-activity relationships, drug absorption, distribution, metabolism, elimination, toxicology and pharmacogenomics. In general, special volumes are edited by well known guest editors.
Chemistry. --- Medicinal Chemistry. --- Receptors. --- Pharmaceutical Sciences/Technology. --- Pharmaceutical technology. --- Biochemistry. --- Cell receptors. --- Chimie --- Techniques pharmaceutiques --- Biochimie --- Récepteurs cellulaires --- Chemokines -- Receptors -- Effect of drugs on. --- Chemokines. --- Immunology. --- Natural immunity. --- Inflammation Mediators --- Receptors, Cytokine --- Investigative Techniques --- Cytokines --- Antigens, CD --- Receptors, G-Protein-Coupled --- Chemistry, Pharmaceutical --- Chemotactic Factors --- Pharmacology --- Biological Factors --- Intercellular Signaling Peptides and Proteins --- Receptors, Immunologic --- Receptors, Cell Surface --- Chemistry --- Antigens, Differentiation --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Biological Science Disciplines --- Natural Science Disciplines --- Biological Markers --- Antigens, Surface --- Membrane Proteins --- Proteins --- Chemicals and Drugs --- Peptides --- Antigens --- Amino Acids, Peptides, and Proteins --- Disciplines and Occupations --- Drug Discovery --- Receptors, Chemokine --- Chemokines --- Biology --- Health & Biological Sciences --- Pharmacy, Therapeutics, & Pharmacology --- Microbiology & Immunology --- Chemotactic cytokines --- Inflammatory peptides --- Intercrines --- Medicinal chemistry. --- Proteins. --- Inflammation --- Mediators --- Pharmaceutical laboratory techniques --- Pharmaceutical laboratory technology --- Technology, Pharmaceutical --- Technology --- Cell membrane receptors --- Cell surface receptors --- Receptors, Cell --- Binding sites (Biochemistry) --- Cell membranes --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Medical sciences --- Composition --- Proteins . --- Chemistry, Medical and pharmaceutical --- Drug chemistry --- Drugs --- Medical chemistry --- Medicinal chemistry --- Pharmacochemistry --- Proteids --- Biomolecules --- Polypeptides --- Proteomics
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The aim of the issue is to describe and explain the importance of the chemokine system in hematology. As described in the introduction the chemokine system is probably important for many aspects of normal as well as malignant hematopoiesis. A major focus is the development and treatment of hematologic malignancies, including the immunobiology of stem cell transplantation.” The present reviews illustrate that chemokines can be involved in leukemogenesis. The chemokine system is also important both for the crosstalk between malignant cells and their neighbouring nonmalignant stromal cells (including endothelial cells) as well as for immunoregulation in patients treated with allogeneic stem cell transplantation. Thus, chemokines are important both for the pathogenesis and treatment of hematological diseases.
Blood -- Diseases -- Immunological aspects. --- Blood -- Diseases. --- Chemokines. --- Hematology, Experimental. --- Hematology. --- Chemokines --- Hematology, Experimental --- Blood --- Antigens, CD --- Cell Transplantation --- Cytokines --- Inflammation Mediators --- Chemotaxis --- Chemotactic Factors --- Biological Science Disciplines --- Receptors, G-Protein-Coupled --- Receptors, Cytokine --- Leukemia, Myeloid --- Immune System Diseases --- Chemotaxis, Leukocyte --- Stem Cell Transplantation --- Receptors, Chemokine --- Graft vs Host Disease --- Leukemia, Myeloid, Acute --- Physiology --- Leukemia --- Natural Science Disciplines --- Biological Factors --- Intercellular Signaling Peptides and Proteins --- Antigens, Differentiation --- Diseases --- Transplantation --- Receptors, Immunologic --- Cell Movement --- Receptors, Cell Surface --- Biological Markers --- Peptides --- Neoplasms by Histologic Type --- Proteins --- Disciplines and Occupations --- Chemicals and Drugs --- Surgical Procedures, Operative --- Antigens, Surface --- Membrane Proteins --- Cell Physiological Processes --- Amino Acids, Peptides, and Proteins --- Neoplasms --- Antigens --- Cell Physiological Phenomena --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Phenomena and Processes --- Medicine --- Biology --- Oncology --- Microbiology & Immunology --- Health & Biological Sciences --- Immunological aspects. --- Chemotactic cytokines --- Inflammatory peptides --- Intercrines --- Experimental hematology --- Haematology --- Medicine. --- Cancer research. --- Biomedicine. --- Cancer Research. --- Internal medicine --- Cancer research --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Medical sciences --- Pathology --- Physicians --- Inflammation --- Medicine, Experimental --- Physiology, Experimental --- Body fluids --- Fear of blood --- Mediators --- Oncology. --- Tumors
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Chemokines and their receptors are being recognized as an integral component of the nervous system implicated in fundamental aspects of development and homeostasis, such as neurotransmission, proliferation, differentiation, and neuronal-glial communication. Thus, their involvement in HIV neuropathology goes far beyond the co-receptors role and entails complex interactions of the chemokine system with different cell types and other regulators of neuronal function. The major goal of this volume is to review these topics in order to highlight alterations of chemokine physiology that may contribute to neuroAIDS and other neuropathologies. This book will be of interest to neuroscientists, neurologists, virologists, pharmacologists, and students in these fields. About the Editor: Olimpia Meucci, MD, PhD is a Professor of Pharmacology and Physiology & Microbiology and Immunology at Drexel University College of Medicine in Philadelphia, PA. Since her seminal discovery about the regulation of neuronal signaling by chemokines, her research has primarily focused on the physio-pathological roles of this important class of neuroimmune modulators in the central nervous system and their involvement in neuroAIDS. These studies have significantly contributed to current understanding of the cellular and molecular mechanisms of HIV-related neuropathology including the interaction of the chemokine system with drug of abuse, namely opiates, which continues to be a major area of investigation in the Meucci lab.
AIDS (Disease) -- Complications -- Treatment. --- Chemokines -- Receptors. --- Chemokines. --- HIV infections -- Complications -- Treatment. --- Chemokines --- AIDS (Disease) --- HIV infections --- Nervous system --- Antigens, CD --- Cytokines --- Diseases --- Immunologic Deficiency Syndromes --- Inflammation Mediators --- Receptors, Cytokine --- Sexually Transmitted Diseases, Viral --- Biological Science Disciplines --- Slow Virus Diseases --- Receptors, G-Protein-Coupled --- Lentivirus Infections --- Chemotactic Factors --- Physiology --- Acquired Immunodeficiency Syndrome --- Nervous System Diseases --- HIV Infections --- Receptors, Chemokine --- Immune System Diseases --- Intercellular Signaling Peptides and Proteins --- Antigens, Differentiation --- Sexually Transmitted Diseases --- Biological Factors --- Natural Science Disciplines --- Retroviridae Infections --- Receptors, Cell Surface --- Receptors, Immunologic --- Virus Diseases --- Proteins --- Chemicals and Drugs --- Disciplines and Occupations --- Antigens, Surface --- RNA Virus Infections --- Peptides --- Membrane Proteins --- Biological Markers --- Amino Acids, Peptides, and Proteins --- Antigens --- Medicine --- Biology --- Microbiology & Immunology --- Neurology --- Health & Biological Sciences --- Receptors --- Complications --- Treatment --- Chemotherapy --- Receptors. --- Treatment. --- Chemotherapy. --- HIV (Viruses) infections --- HTLV-III infections --- HTLV-III-LAV infections --- Human T-lymphotropic virus III infections --- Acquired immune deficiency syndrome --- Acquired immunodeficiency syndrome --- Acquired immunological deficiency syndrome --- Chemotactic cytokines --- Inflammatory peptides --- Intercrines --- Medicine. --- Neurosciences. --- Pharmacology. --- Virology. --- Infectious diseases. --- Biomedicine. --- Pharmacology/Toxicology. --- Infectious Diseases. --- Organs (Anatomy) --- Neurosciences --- Lentivirus infections --- Sexually transmitted diseases --- Immunological deficiency syndromes --- Virus-induced immunosuppression --- Inflammation --- Mediators --- Medical virology. --- Toxicology. --- Emerging infectious diseases. --- Emerging infections --- New infectious diseases --- Re-emerging infectious diseases --- Reemerging infectious diseases --- Communicable diseases --- Chemicals --- Pharmacology --- Poisoning --- Poisons --- Medical microbiology --- Virology --- Virus diseases --- Neural sciences --- Neurological sciences --- Neuroscience --- Medical sciences --- Toxicology --- Drug effects --- Medical pharmacology --- Drugs --- Pharmacy --- Microbiology --- Physiological effect
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We are entering one of the most exciting periods in the study of chemical communication since the first pheromones were identified some 40 years ago. This rapid progress is reflected in this book, the first to cover the whole animal kingdom at this level for 25 years. The importance of chemical communication is illustrated with examples from a diverse range of animals including humans, marine copepods, Drosophila, Caenorhabditis elegans, moths, snakes, goldfish, elephants and mice. It is designed to be advanced, but at the same time accessible to readers whatever their scientific background. For students of ecology, evolution and behaviour, this book gives an introduction to the rapid progress in our understanding of olfaction at the molecular and neurological level. In addition, it offers chemists, molecular and neurobiologists an insight into the ecological, evolutionary and behavioural context of olfactory communication.
Animal communication. --- Chemical senses. --- Pheromones. --- Animal communication --- Pheromones --- Chemical senses --- Behavior, Animal --- Sensory Receptor Cells --- Biological Factors --- Chemicals and Drugs --- Neurons, Afferent --- Behavior --- Peripheral Nervous System --- Behavior and Behavior Mechanisms --- Neurons --- Nervous System --- Cells --- Anatomy --- Psychiatry and Psychology --- Chemoreceptor Cells --- Animal Communication --- Zoology --- Health & Biological Sciences --- Animal Behavior --- Synomones --- Allelochemical --- Allelochemicals --- Allomone --- Allomones --- Ectohormones --- Kairomone --- Kairomones --- Pheromone --- Semiochemical --- Semiochemicals --- Chemotactic Factors --- Animal Communications --- Communication, Animal --- Communications, Animal --- Chemoreceptive Cells --- Cell, Chemoreceptive --- Cell, Chemoreceptor --- Cells, Chemoreceptive --- Cells, Chemoreceptor --- Chemoreceptive Cell --- Chemoreceptor Cell --- Chemotaxis --- Sensilla --- Anatomies --- Cell --- Cell Biology --- Nervous Systems --- System, Nervous --- Systems, Nervous --- Nerve Cells --- Cell, Nerve --- Cells, Nerve --- Nerve Cell --- Neuron --- Behavior And Behavior Mechanism --- Nervous System, Peripheral --- Nervous Systems, Peripheral --- Peripheral Nervous Systems --- System, Peripheral Nervous --- Systems, Peripheral Nervous --- Acceptance Process --- Acceptance Processes --- Behaviors --- Process, Acceptance --- Processes, Acceptance --- Afferent Neurons --- Afferent Neuron --- Neuron, Afferent --- Biologic Agents --- Biologic Factors --- Biological Factor --- Factor, Biologic --- Factor, Biological --- Factors, Biological --- Biologic Agent --- Biological Agent --- Biological Agents --- Agent, Biologic --- Agent, Biological --- Agents, Biologic --- Agents, Biological --- Biologic Factor --- Factors, Biologic --- Biological Products --- Neural Receptors --- Receptors, Sensory --- Sensory Neurons --- Sensory Receptors --- Nerve Endings, Sensory --- Neurons, Sensory --- Neuroreceptors --- Receptors, Neural --- Nerve Ending, Sensory --- Neural Receptor --- Neuron, Sensory --- Neuroreceptor --- Receptor Cell, Sensory --- Receptor Cells, Sensory --- Receptor, Neural --- Receptor, Sensory --- Sensory Nerve Ending --- Sensory Nerve Endings --- Sensory Neuron --- Sensory Receptor --- Sensory Receptor Cell --- Sense Organs --- Autotomy Animal --- Animal Behaviors --- Ethology --- Chemoreception --- Senses and sensation --- Chemoreceptors --- Hormones --- Sex recognition (Zoology) --- Animal biocommunication --- Animal language --- Biocommunication, Animal --- Language learning by animals --- Animal behavior --- Animal population --- Communication --- social behaviour --- Sexual behaviour --- Olfactory organs --- Communication animale --- Phéromones --- Chémoréception
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