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Autoimmunity is defined as an immune response against a self-antigen. This abnormal immune response can lead to tissue damage and to the development of autoimmune disease. From organ-specific autoimmune diseases, such as myasthenia gravis, to non-organ-specific, such as systemic lupus erythematosus, autoimmune diseases represent a heterogeneous group of disorders which affect approximately 6% of the population. The pathogenesis of many autoimmune diseases is complex and remains not completely understood. The aim of this book is to present current knowledge regarding pathogenic mechanisms of autoimmune diseases, clinical aspects of specific autoimmune diseases, like vitiligo, celiac disease and autoimmune liver disease, as well as insights regarding specific therapies.

Autoimmune diseases --- Treatment. --- Autoimmunologic diseases --- Autoimmunity --- Immunologic diseases --- Immunology

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The new edition covers recent scientific advances, diagnostic techniques, and therapeutic technologies. Each chapter is focused on a single family of autoantibodies. This important reference contains historical notes, definitions, origins and sources of antigens recognized genetic associations, mediated pathogenic mechanisms, methods of detection, as well as clinical utility (disease prevalence and association, diagnostic value, sensitivity and specificity, prognostic value). -- Publisher This book covers recent scientific advances, diagnostic techniques, and therapeutic technologies in the field of autoimmune diseases. Each chapter is focused on a single family of autoantibodies, providing historical notes, origins and sources of antigens recognized genetic associations, mediated pathogenic mechanisms, methods of detection, as well as clinical utility (disease prevalence and association, diagnostic value, sensitivity and specificity, prognostic value).

Autoantibodies. --- Autoimmune diseases --- Etiology. --- Autoimmune Diseases --- etiology. --- Autoimmunity --- Autoimmunologic diseases --- Immunologic diseases --- Immunoglobulins

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The present edition entitled "Autoimmune disorders - Pathogenetic aspects" aims to present the current available evidence of etiopathogenetic insights of both systemic and organ specific autoimmune disorders, the crossover interactions among autoimmunity, cardiovascular morbidity and malignancy as well as novel findings in the exciting fields of osteoimmunology and immunology of pregnancy.

Autoimmune diseases. --- Immunology. --- Immunobiology --- Life sciences --- Serology --- Autoimmunologic diseases --- Autoimmunity --- Immunologic diseases --- Immunology

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Epithelial tissue does not spring to mind as an obvious source of autoimmune phenomena. Yet, genetic predisposition and influence of various environmental and epigenetic factors may lead to epithelium becoming a springboard for the development of autoimmune diseases, such as Sjögren’s syndrome, primary biliary cholangitis, autoimmune pancreatitis, or IgG4-related diseases. This book is intended as an introduction to the problem of “autoimmune epithelitis” and diseases closely related to the immune disturbances of the epithelium, with special emphasis on those affecting exocrine glands. Both theoretical and practical knowledge, presented by authors from a wide range of medical specialties, should be of help for medical professionals who have to deal with this difficult problem in their daily practice.

Autoimmune diseases. --- Autoimmunologic diseases --- Autoimmunity --- Immunologic diseases --- Medicine --- Clinical Immunology --- Immunology --- Allergology and Rheumatology --- Health Sciences

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Autoimmune diseases --- Interferon --- Autoimmunologic diseases --- Autoimmunity --- Immunologic diseases --- Immunotherapy. --- Therapeutic use.