Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

The history of science can teach modern men that our understanding of life is to a great extent based on the accuracy of the analytical methods that we use and, on our readiness to oppose dogmatic opinions, which are based on outdated methods and black/white approaches to the major questions raised by mankind in the past. The recent decades have brought a lot of new insights into the fundamentals of the active principles of reactive oxygen species that are necessary for living cells, but which also cause dangerous pathophysiological processes. Accordingly, although they were previously considered to be the most undesired toxic compounds generated as the final products of the oxidative degradation of lipids, reactive aldehydes are now considered to play important roles both in health and in major diseases. Represented mostly by 4-hydroxynonenal (HNE), a substance discovered only fifty years ago, reactive aldehydes are the focus of research not only because of their toxicity but also because of their positive effects regulating the most important metabolic processes such as growth of living cells or the death of cells. Better understanding the interactions between reactive aldehydes and natural or synthetic antioxidant substances might eventually help us to better monitor, prevent and control modern diseases, thus building pillars for the development of the modern, multidisciplinary life sciences and integrative medicine of the 21st century.

free radicals --- lipids --- cell-based ELISA --- reactive aldehydes --- antioxidants --- fertility --- reactive oxygen species ROS --- human diseases --- lipid peroxidation --- 4-hydroxynonenal --- 1 --- 4-Dihydropyridine Derivatives --- omics --- pathophysiology --- growth control --- cannabinoids --- plant extract --- mass spectrometry --- cell cultures --- cancer --- aging --- oxidative stress --- immunochemistry

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Medicinal plants are used to treat diseases and provide health benefits, and their applications are increasing around the world. A huge array of phytochemicals have been identified from medicinal plants, belonging to carotenoids, flavonoids, lignans, and phenolic acids, and so on, with a wide range of biological activities. In order to explore our knowledge of phytochemicals with the assistance of modern molecular tools and high-throughput technologies, this book collects recent innovative original research and review articles on subtopics of mechanistic insights into bioactivities, treatment of diseases, profiling, extraction and identification, and biotechnology.

Medicine --- network pharmacology --- traditional herbal medicine --- methodological trend --- polysaccharide fraction --- Trichoderma atroviride --- Salvia miltiorrhiza --- proteomics --- tanshinones --- Flos Chrysanthemi indici --- essential oil --- extraction method --- chemical composition --- biological activity --- Garcinia linii --- hypoglycemia --- benzopyran --- triterpene --- bioflavonoid --- phenolic --- in silico --- neurodegenerative diseases --- naringenin --- pharmacological targets --- signaling pathways --- molecular mechanisms --- drug delivery systems --- luteolin --- hyphenated techniques --- chromatography --- colorectal cancer --- diterpenes --- inflammatory bowel diseases --- Polyalthia longifolia --- herbal medicine --- DESs --- preparative-scale purification --- flavonoids --- 20-hydroxyecdysone --- Chenopodium quinoa --- Zinc oxide nanoparticles --- anticancer --- antileishmanial --- antimicrobial --- biocompatibility --- cancer --- apoptosis --- herbs --- cell lines --- in vivo --- quercetin --- polyphenols --- Alzheimer's disease --- mechanistic insights --- clinical directions --- isodon genus --- ent-kaurane diterpenoids --- natural compounds --- pathways --- medicinal plants --- bioactive compounds --- 4-hydroxynonenal --- deleterious effects --- Asiatic acid --- nasopharyngeal cancer --- cisplatin resistance --- MAPK pathway --- Anthocyanin --- Solanum nigrum L. --- flavonoid biosynthesis --- AtPAP1 --- licochalcone D --- non-small cell lung cancer --- reactive oxygen species --- Acorus gramineusand --- Euodia ruticarpa --- pro-/anti-inflammatory cytokines --- steam distillation essential oil --- Th1/Th2 cytokines --- lignans --- Trachelospermum asiaticum --- GNPS --- targeted isolation --- Rheum undulatum --- Glycyrriza uralensis --- hepatic encephalopathy --- MMP-9 --- neuroinflammation --- luteolin-7-O-glucoside --- oral cancer --- migration --- invasion --- MMP-2 --- Astragalus mongholicus --- ultraviolet-B radiation --- phenolics --- untargeted gas chromatography-mass spectrometry --- targeted liquid chromatography-mass spectrometry --- Bacopa monnieri --- cheminformatics --- neurological diseases --- spinocerebellar ataxia --- system pharmacology --- (-)-epigallocatechin-3-gallate (EGCG) --- bone morphogenetic protein-2 (BMP-2) --- catethin --- fracture healing --- local use --- cardiovascular diseases --- inflammation --- lipid metabolism --- non-coding RNA --- oxidative stress --- phenolic compounds --- Peucedanum ostruthium --- Apiaceae --- ELINA --- HetCA, STOCSY --- coumarines --- NF-ĸB --- VCAM-1 --- E-selectin --- Withaferin A --- matrix metalloproteinases --- antioxidant signaling --- Curcuma aromatica --- sesquiterpene --- anti-inflammatory --- luciferase assay --- cytotoxicity

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Medicinal plants are used to treat diseases and provide health benefits, and their applications are increasing around the world. A huge array of phytochemicals have been identified from medicinal plants, belonging to carotenoids, flavonoids, lignans, and phenolic acids, and so on, with a wide range of biological activities. In order to explore our knowledge of phytochemicals with the assistance of modern molecular tools and high-throughput technologies, this book collects recent innovative original research and review articles on subtopics of mechanistic insights into bioactivities, treatment of diseases, profiling, extraction and identification, and biotechnology.

network pharmacology --- traditional herbal medicine --- methodological trend --- polysaccharide fraction --- Trichoderma atroviride --- Salvia miltiorrhiza --- proteomics --- tanshinones --- Flos Chrysanthemi indici --- essential oil --- extraction method --- chemical composition --- biological activity --- Garcinia linii --- hypoglycemia --- benzopyran --- triterpene --- bioflavonoid --- phenolic --- in silico --- neurodegenerative diseases --- naringenin --- pharmacological targets --- signaling pathways --- molecular mechanisms --- drug delivery systems --- luteolin --- hyphenated techniques --- chromatography --- colorectal cancer --- diterpenes --- inflammatory bowel diseases --- Polyalthia longifolia --- herbal medicine --- DESs --- preparative-scale purification --- flavonoids --- 20-hydroxyecdysone --- Chenopodium quinoa --- Zinc oxide nanoparticles --- anticancer --- antileishmanial --- antimicrobial --- biocompatibility --- cancer --- apoptosis --- herbs --- cell lines --- in vivo --- quercetin --- polyphenols --- Alzheimer’s disease --- mechanistic insights --- clinical directions --- isodon genus --- ent-kaurane diterpenoids --- natural compounds --- pathways --- medicinal plants --- bioactive compounds --- 4-hydroxynonenal --- deleterious effects --- Asiatic acid --- nasopharyngeal cancer --- cisplatin resistance --- MAPK pathway --- Anthocyanin --- Solanum nigrum L. --- flavonoid biosynthesis --- AtPAP1 --- licochalcone D --- non-small cell lung cancer --- reactive oxygen species --- Acorus gramineusand --- Euodia ruticarpa --- pro-/anti-inflammatory cytokines --- steam distillation essential oil --- Th1/Th2 cytokines --- lignans --- Trachelospermum asiaticum --- GNPS --- targeted isolation --- Rheum undulatum --- Glycyrriza uralensis --- hepatic encephalopathy --- MMP-9 --- neuroinflammation --- luteolin-7-O-glucoside --- oral cancer --- migration --- invasion --- MMP-2 --- Astragalus mongholicus --- ultraviolet-B radiation --- phenolics --- untargeted gas chromatography-mass spectrometry --- targeted liquid chromatography-mass spectrometry --- Bacopa monnieri --- cheminformatics --- neurological diseases --- spinocerebellar ataxia --- system pharmacology --- (-)-epigallocatechin-3-gallate (EGCG) --- bone morphogenetic protein-2 (BMP-2) --- catethin --- fracture healing --- local use --- cardiovascular diseases --- inflammation --- lipid metabolism --- non-coding RNA --- oxidative stress --- phenolic compounds --- Peucedanum ostruthium --- Apiaceae --- ELINA --- HetCA, STOCSY --- coumarines --- NF-ĸB --- VCAM-1 --- E-selectin --- Withaferin A --- matrix metalloproteinases --- antioxidant signaling --- Curcuma aromatica --- sesquiterpene --- anti-inflammatory --- luciferase assay --- cytotoxicity --- n/a --- Alzheimer's disease