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Drug development is very expensive and a fight against time. PET offers possibilities to speed up this process by adding unique in vivo information on pharmacokinetics/dynamics of a drug at an early stage. This information can help decision makers to move the drug in the drug development process or to decide to stop further developments. This unique and complete book highlights the different ways PET can be used and describes the latest trends in the various disciplines within nuclear medicine to further improve methodologies and increase the number of tools to accelerate drug development. Var

Drug development. --- Polyethylene terephthalate. --- Ethylene terephthalate polymer --- Mylar (Trademark) --- PET (Chemical) --- Terephthalic acid-ethylene glycol polymer --- Phthalate esters --- Polyesters --- Thermoplastics --- Development of drugs --- Drugs --- New drug development --- Pharmacology --- Pharmacy --- Development

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PET and SPECT in Psychiatry showcases the combined expertise of renowned authors whose dedication to the investigation of psychiatric disease through nuclear medicine technology has achieved international recognition. The classical psychiatric disorders as well as other subjects – such as suicide, sleep, eating disorders, and autism – are discussed and the latest results in functional neuroimaging are detailed. Most chapters are written jointly by a clinical psychiatrist and a nuclear medicine expert to ensure a multidisciplinary approach. This state of the art compendium will be valuable to all who have an interest in the field of neuroscience, from the psychiatrist and the radiologist/nuclear medicine specialist to the interested general practitioner and cognitive psychologist. It is the first volume of a trilogy on PET and SPECT imaging in the neurosciences; other volumes will focus on PET and SPECT in neurology and PET and SPECT of neurobiological systems.

Psychiatry --- Tomography, Emission --- Single-photon emission computed tomography --- Research. --- SPECT (Tomography) --- Computerized emission tomography --- Emission tomography --- PET (Tomography) --- PET-CT (Tomography) --- Positron emission tomography --- Positron emission transaxial tomography --- Radionuclide tomography --- Scintigraphy, Tomographic --- Tomography, Radionuclide --- Diagnosis --- Diagnostic imaging --- Positrons --- Radioisotope scanning --- Mental health --- Mental illness --- Psychiatric research --- Psychology, Pathological --- Data processing --- Emission --- Research --- Nuclear medicine. --- Radiology, Medical. --- Psychiatry. --- Nuclear Medicine. --- Imaging / Radiology. --- Medicine and psychology --- Clinical radiology --- Radiology, Medical --- Radiology (Medicine) --- Medical physics --- Atomic medicine --- Radioisotopes in medicine --- Medical radiology --- Radioactive tracers --- Radioactivity --- Physiological effect --- Radiology. --- Radiological physics --- Physics --- Radiation

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PET and SPECT of Neurobiological Systems combines the expertise of renowned authors whose dedication to the development of novel probes and techniques for the investigation of neurobiological systems has achieved international recognition. Various aspects of neurotransmission in the brain are discussed, such as visualization and quantification of (more than 20 different) neuroreceptors, neuroinflammatory markers, transporters, and enzymes as well as neurotransmitter synthesis, β-amyloid deposition, cerebral blood flow, and the metabolic rate of glucose. The latest results in probe development are also detailed. Most chapters are written jointly by radiochemists and nuclear medicine specialists to ensure a multidisciplinary approach. This state of the art compendium will be valuable to anyone in the field of clinical or preclinical neuroscience, from the radiochemist and radiologist/nuclear medicine specialist to the interested neurobiologist and general practitioner. It is the second volume of a trilogy on PET and SPECT imaging in the neurosciences. Other volumes focus on PET and SPECT in psychiatry and PET and SPECT in neurology".

Medicine. --- Neurology. --- Nuclear medicine. --- Radiology, Medical. --- Tomography, Emission. --- Tomography, Emission-Computed --- Neurosciences --- Biology --- Investigative Techniques --- Biological Science Disciplines --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Image Enhancement --- Radionuclide Imaging --- Tomography --- Image Interpretation, Computer-Assisted --- Diagnostic Imaging --- Diagnostic Techniques, Radioisotope --- Natural Science Disciplines --- Photography --- Diagnostic Techniques and Procedures --- Disciplines and Occupations --- Diagnosis --- Positron-Emission Tomography --- Tomography, Emission-Computed, Single-Photon --- Neurobiology --- Methods --- Medicine --- Health & Biological Sciences --- Radiology, MRI, Ultrasonography & Medical Physics --- Neurology --- Atomic medicine --- Radioisotopes in medicine --- Computerized emission tomography --- Emission tomography --- PET (Tomography) --- PET-CT (Tomography) --- Positron emission tomography --- Positron emission transaxial tomography --- Radionuclide tomography --- Scintigraphy, Tomographic --- Tomography, Radionuclide --- Radiology. --- Medicine & Public Health. --- Nuclear Medicine. --- Imaging / Radiology. --- Medical radiology --- Radioactive tracers --- Radioactivity --- Physiological effect --- Diagnostic imaging --- Positrons --- Radioisotope scanning --- Data processing --- Emission --- Nervous system --- Neuropsychiatry --- Clinical radiology --- Radiology, Medical --- Radiology (Medicine) --- Medical physics --- Diseases --- Neurology . --- Radiological physics --- Physics --- Radiation

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Physical methods for diagnosis --- Psychiatry --- psychiatrie --- radiologie --- medische beeldvorming