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Intellectual disability facilities --- People with mental disabilities --- History. --- Institutional care --- Pineland Hospital and Training Center (New Gloucester, Me.) --- Mental retardation facilities

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"Ecological restoration is a rapidly evolving discipline that is engaged with developing both methodologies and strategies for repairing damaged and polluted ecosystems and environments. During the last decade the rapid pace of climate change coupled with continuing habitat destruction and the spread of non-native species to new habitats has forced restoration ecologists to re-evaluate their goals and the methods they use. This comprehensive handbook brings together an internationally respected group of established and rising experts in the field. The book begins with a description of current practices and the state of knowledge in particular areas of restoration, and then identifies new directions that will help the field achieve increasing levels of future success. Part I provides basic background about ecological and environmental restoration. Part II systematically reviews restoration in key ecosystem types located throughout the world. In Part III, management and policy issues are examined in detail, offering the first comprehensive treatment of policy relevance in the field, while Part IV looks to the future. Ultimately, good ecological restoration depends upon a combination of good science, policy, planning and outreach - all issues that are addressed in this unrivalled volume."--Provided by publisher.

Restoration ecology.

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Parue en 1546, cette première traduction intégrale en français du commentaire sur Le banquet de Platon par le philosophe Marsille Ficin révèle un remarquable traducteur en la personne de Symon Silvius, valet de chambre de Marguerite de Navarre. Les enjeux philologiques, linguistiques et historiques de ce texte sont explorés.

Platon (0427?-0348?)

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Since the 1984 passage of the Waxman-Hatch Act, generic prescription drugs have become central to disease treatment and generic drug entry and price competition has been vigorous in the U.S. Nonetheless, recent policy concern has focused on potential supply inadequacy and price increases among selected generic drugs. Details regarding the supply of generic drugs throughout the product life cycle are surprisingly unstudied. Here, we examine manufacturer entry, exit, the extent of competition and the relationship between supply structure and inflation adjusted prices among generic drugs. Our empirical approach is descriptive and reduced form, following recent innovations on the older structure-conduct-performance tradition. We employ quarterly national data on quantities, wholesale dollar sales and manufacturers from QuintilesIMS National Sales Perspective data, 2004Q4-2016Q3. Defining a market as the molecule-dosage-form, we observe that median sizes of drug markets are predominantly small, with annual inflation adjusted sales revenues of less than $10 million but increasing over time. The median number of manufacturers in each market is about two, the mean about four. We find evidence to suggest decreasing numbers of suppliers over our study period, particularly following implementation of the Affordable Care Act in 2010 and the Generic Drug User Fee Amendments of 2012, attributable both to more exit and less entry. Approximately 40 percent of markets are supplied by one manufacturer; the share of markets supplied by one or two manufacturers is observed to increase over time and is more likely among non-oral drugs and those belonging to selected therapeutic classes. We find evidence to suggest prices of generic drugs are statistically significantly increasing over time, particularly following the implementation of the 2010 Affordable Care Act and the 2012 Generic Drug User Fee Amendments. Price increases are positively correlated with reduced manufacturer counts and alternative measures of increased supplier concentration, holding all else constant. Our results suggest the market for generic drugs is largely comprised of small revenue products the supply of which has tended towards duopoly or monopoly in recent years. Therefore, it is surprising generic drug prices have not been observed to be higher and potentially risen more over our study period. This issue merits further study; we suggest several testable hypotheses based in economic theory.

Zonder onderwerpscode: economie

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Sherman's March through the Carolinas. --- Sherman's March to the Sea. --- Scouts (Reconnaissance) --- Soldiers --- Quimby, George W., --- United States --- History --- Campaigns. --- Scouts and scouting.