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This book examines the role of bioactive lipids as pro- and anti-inflammatory mediators in the diagnosis of and as novel therapies for cardiovascular disease, cancer, ocular and neurologic diseases, and inflammatory conditions. The major pathways of arachidonic acid and omega-3 fatty acid metabolism are represented, including cyclooxygenases, lipoxygenases, cytochrome P450 monooxygenases, specialized pro-resolving mediators, endocannabinoids, and ceramide and other sphingolipids. This book would be of great interest to basic and translational researchers, as well as physician-scientists working on selected topics (e.g., cancer, cardiovascular disease, stroke, diabetes, inflammation, etc.) in which the underlying role of lipid mediators in the pathophysiology is known or suspected. This compilation of peer-reviewed manuscripts represents reviews of timely topics presented at the 15th International Conference on Bioactive Lipids in Cancer, Inflammation and Related Diseases. Authors selected are outstanding junior investigators representative of future leaders in the field of bioactive lipids.

Human genetics. --- Lipids. --- Human physiology. --- Cytology. --- Oncology. --- Medicine. --- Human Genetics. --- Lipidology. --- Human Physiology. --- Cell Biology. --- Cancer Research. --- Molecular Medicine. --- Health Workforce --- Tumors --- Cell biology --- Cellular biology --- Biology --- Cells --- Cytologists --- Human biology --- Medical sciences --- Physiology --- Human body --- Lipides --- Lipins --- Lipoids --- Biomolecules --- Steroids --- Genetics --- Heredity, Human --- Physical anthropology --- Cell biology. --- Cancer research. --- Molecular biology. --- Molecular biochemistry --- Molecular biophysics --- Biochemistry --- Biophysics --- Systems biology --- Cancer research

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Prostate cancer (PCa) is the most common newly diagnosed cancer among men in the United States today. With the advent of the prostate-specific antigen (PSA) test, the number of newly diagnosed cases has increased tremendously. The rates of PCa have increased so dramatically over the last decade that the age-adjusted incidence rate of PCa is no greater than that for any other cancer among men in the United States. Although PCa rates have risen steadily since 1973, there has been a dramatic acceleration in the late 1980s which has been associated with the introduction and use of PSA for screenin

Prostate --- Cancer. --- Cancer --- Molecular aspects.

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