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The past twenty years have seen remarkable advances in neuroscience, neurology, imaging techniques, and diagnostic strategies. These advances have been successfully applied to many different diseases, including thiamine deficiency and associated clinical disorders. Syndromes such as beriberi, Wernicke’s disease, Leigh’s disease, African Seasonal Ataxia, and various inherited ataxias, have all benefited from improved scientific approaches. Thiamine Deficiency and Associated Clinical Disorders represents an intriguing area of both basic and clinical investigation. Modern imaging and diagnostic strategies have facilitated the rapid treatment, and potential reversal of these clinical disorders. The fusion of laboratory and clinical knowledge serve as an example of how research can translate to successful treatment. This book is designed to bring together cogent results from both basic and clinical investigation. These data will be of interest to neurologists, internists, nutritionists, biochemists, neurochemists, neuroscientists, and many others with interest in thiamine deficiency. About the Author: Dr. David W. McCandless is the John J. Sheinin Professor of Anatomy in the Department of Cell Biology and Anatomy at The Chicago Medical School, Rosalind Franklin University, North Chicago, IL, USA. He has over 35 years of laboratory research into basic mechanisms of various metabolic encephalopathies. He serves as Editor-in Chief of the journal Metabolic Brain Disease (Springer), now in its 25th year. Dr. McCandless has been on the faculty or research staff at The University of Vermont College of Medicine, NIH-NINCDS, University of Texas Medical School at Houston, and The Chicago Medical School, and was a visiting professor at Washington University School of Medicine. Dr. McCandless has published in journals such as The J. Clinical Investigation, Nature, Proc. National Academy of Sciences, Amer. J. of Physiology, Brain Research, J. Neurochemistry, Teratology, Epilepsia, Stroke, and many others.

Deficiency diseases. --- Nutritionally induced diseases. --- Vitamin B1 deficiency. --- Deficiency diseases --- Nutritionally induced diseases --- Vitamin B1 deficiency --- Thiamine Deficiency --- Vitamin B Deficiency --- Avitaminosis --- Deficiency Diseases --- Malnutrition --- Nutrition Disorders --- Nutritional and Metabolic Diseases --- Diseases --- Metabolic & Nutritional Diseases --- Neurology --- Animal Biochemistry --- Medicine --- Human Anatomy & Physiology --- Health & Biological Sciences --- Ataxia. --- Thiamine deficiency --- Medicine. --- Neurosciences. --- Neurochemistry. --- Food --- Nutrition. --- Public health. --- Neurology. --- Medicine & Public Health. --- Public Health. --- Food Science. --- Biotechnology. --- Nervous system --- Neuropsychiatry --- Community health --- Health services --- Hygiene, Public --- Hygiene, Social --- Public health services --- Public hygiene --- Sanitary affairs --- Social hygiene --- Health --- Human services --- Biosecurity --- Health literacy --- Medicine, Preventive --- National health services --- Sanitation --- Alimentation --- Nutrition --- Physiology --- Diet --- Dietetics --- Digestion --- Food habits --- Food biotechnology --- Biotechnology --- Genetically modified foods --- Biochemistry --- Neurosciences --- Neural sciences --- Neurological sciences --- Neuroscience --- Medical sciences --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Pathology --- Physicians --- Health aspects --- Movement disorders --- Food science. --- Science --- Neurology . --- Food—Biotechnology. --- Nutrition   .