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Huntington's disease is a progressive neurodegenerative disorder of the brain. It is one of the quite devastating and currently incurable human conditions. Degeneration of specific types of neurons in the brain results in a triad of clinical features: serious behavioral disturbances, uncontrolled movements of body parts, and deterioration of intellectual capabilities. The underlying complex mechanisms and molecular players of the cellular cascades still need to be deciphered in detail despite considerable advances. Once solved, the related molecular mechanisms will not only enlighten the HD story but will also shed light on other polyglutamine diseases and similar brain disorders. This book, Huntington's Disease-Molecular Pathogenesis and Current Models, is planned to cover recent scientific achievements in understanding the cellular mechanisms of HD. The chapters provide comprehensive description of the key issues in HD research. In this regard, this book will serve as a source for clinicians and researchers in the field and also for life science readers in increasing their understanding and awareness of the clinical correlates, genetic aspects, neuropathological findings, and potential therapeutic interventions related to HD.

Huntington's disease. --- Chronic progressive chorea --- Chronic progressive hereditary chorea --- Degenerative chorea --- HC (Disease) --- HD (Disease) --- Hereditary chorea --- Huntington chorea --- Huntington chronic progressive hereditary chorea --- Huntington disease --- Huntington's chorea --- Lund-Huntington chorea --- Microcellular striatal syndrome --- Progressive hereditary chorea, Chronic --- Chorea --- Dementia --- Genetic disorders --- Nervous system --- Degeneration --- Medicine --- Neurology --- Mental and Behavioural Disorders and Diseases of the Nervous System --- Health Sciences

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'This is a moving true story of how people can find the inner strength to rise above it when their world is turned upside down.'. - Richard Branson. Huntington's Disease (HD) is a hereditary illness passed on via a defective gene. There is a fifty per cent chance of inheriting it from a parent and there is yet no cure. Learning to Live with Huntington's Disease is one family's poignant story of coping with the symptoms, the diagnosis and the effects of HD. This book presents the struggles and strengths of the whole family when one member loses their future to a terminal illness. Told by the su

Huntington's chorea --- Chronic progressive chorea --- Chronic progressive hereditary chorea --- Degenerative chorea --- HC (Disease) --- HD (Disease) --- Hereditary chorea --- Huntington chorea --- Huntington chronic progressive hereditary chorea --- Huntington disease --- Lund-Huntington chorea --- Microcellular striatal syndrome --- Progressive hereditary chorea, Chronic --- Chorea --- Dementia --- Genetic disorders --- Nervous system --- Patients --- Family relationships. --- Degeneration --- Sulaiman, Sandy, --- Sulaiman, Sandra Margaret, --- Health. --- Huntington's disease

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Huntington's disease. --- Chronic progressive chorea --- Chronic progressive hereditary chorea --- Degenerative chorea --- HC (Disease) --- HD (Disease) --- Hereditary chorea --- Huntington chorea --- Huntington chronic progressive hereditary chorea --- Huntington disease --- Huntington's chorea --- Lund-Huntington chorea --- Microcellular striatal syndrome --- Progressive hereditary chorea, Chronic --- Chorea --- Dementia --- Genetic disorders --- Nervous system --- Degeneration

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Huntington's chorea. --- Brain --- Brain diseases --- Psychology, Pathological --- Chronic progressive chorea --- Chronic progressive hereditary chorea --- Degenerative chorea --- HC (Disease) --- HD (Disease) --- Hereditary chorea --- Huntington chorea --- Huntington chronic progressive hereditary chorea --- Huntington disease --- Huntington's chorea --- Lund-Huntington chorea --- Microcellular striatal syndrome --- Progressive hereditary chorea, Chronic --- Chorea --- Dementia --- Genetic disorders --- Nervous system --- Diseases. --- Degeneration --- Huntington's disease.

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This book project was initiated at The Tribute Workshop in Honour of Gunnar Sparr and the follow-up workshop Inequalities, Interpolation, Non-commutative Analysis, Non-commutative Geometry and Applications, held at the Centre for Mathematical Sciences, Lund University in May and November of 2008.  The resulting book is dedicated in celebration of Gunnar Sparr's sixty-fifth anniversary and more than forty years of exceptional service to mathematics and its applications in engineering and technology, mathematics and engineering education, as well as interdisciplinary, industrial and international cooperation.   This book presents new advances in several areas of mathematics and engineering mathematics including applications in modern technology, engineering and life sciences.  Thirteen high-quality chapters put forward many new methods and results, reviews of up to date research and open directions and problems for future research. A special chapter by Gunnar Sparr and Georg Lindgren contains a historical account and important aspects of engineering mathematics research and education, and the implementation of the highly successful education programme in Engineering Mathematics at Lund Institute of Technology,  where not only the mathematical sciences have played a role. This book will serve as a source of inspiration for a broad spectrum of researchers and research students.

Engineering mathematics. --- Mathematical analysis. --- Mathematics. --- Mathematical analysis --- Engineering mathematics --- Engineering & Applied Sciences --- Applied Mathematics --- Engineering --- Engineering analysis --- 517.1 Mathematical analysis --- Mathematics --- Analysis (Mathematics). --- Applied mathematics. --- Applications of Mathematics. --- Appl.Mathematics/Computational Methods of Engineering. --- Signal, Image and Speech Processing. --- Analysis. --- Mathematics Education. --- Study and teaching. --- Math --- Science --- Global analysis (Mathematics). --- Mathematical and Computational Engineering. --- Analysis, Global (Mathematics) --- Differential topology --- Functions of complex variables --- Geometry, Algebraic --- Signal processing. --- Image processing. --- Speech processing systems. --- Mathematics—Study and teaching . --- Computational linguistics --- Electronic systems --- Information theory --- Modulation theory --- Oral communication --- Speech --- Telecommunication --- Singing voice synthesizers --- Pictorial data processing --- Picture processing --- Processing, Image --- Imaging systems --- Optical data processing --- Processing, Signal --- Information measurement --- Signal theory (Telecommunication) --- Angewandte Mathematik. --- Lund <2008> --- Engineering—Data processing. --- Mathematics—Study and teaching. --- Mathematical and Computational Engineering Applications. --- Signal, Speech and Image Processing .