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Bacterial virulence factors and Rho GTPases
Authors: ---
ISBN: 1280306319 9786610306312 3540275118 3540238654 3642062806 Year: 2005 Publisher: Berlin ; [Great Britian] : Springer,

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Abstract

Pathogenic bacteria for human and animals have developed sophisticated weapons, termed virulence factors, to ensure their replication and persistence into their hosts. The first role of these virulence factors is to loosen the host defenses against microorganisms represented by innate and adaptive immunities. Small GTPases of the Rho subfamily have been shown top play important functions in theses systems. The authors of this volume present the synthesis on how the various host cellular Rho GTPases activities are manipulated by bacteria to fulfill their virulence.

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