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book (9)


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Book
Water Stress
Authors: --- ---
ISBN: 9535143751 9533079630 Year: 2012 Publisher: IntechOpen

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Abstract

Plants experience water stress either when the water supply to their roots becomes limiting, or when the transpiration rate becomes intense. Water stress is primarily caused by a water deficit, such as a drought or high soil salinity. Each year, water stress on arable plants in different parts of the world disrupts agriculture and food supply with the final consequence: famine. Hence, the ability to withstand such stress is of immense economic importance. Plants try to adapt to the stress conditions with an array of biochemical and physiological interventions. This multi-authored edited compilation puts forth an all-inclusive picture on the mechanism and adaptation aspects of water stress. The prime objective of the book is to deliver a thoughtful mixture of viewpoints which will be useful to workers in all areas of plant sciences. We trust that the material covered in this book will be valuable in building strategies to counter water stress in plants.


Book
New Insights into the Pathogenesis and Therapies of IgA Nephropathy
Authors: ---
Year: 2022 Publisher: Basel MDPI Books

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IgA nephropathy (IgAN) is the most common form of primary glomerulonephritis worldwide and a frequent cause of kidney failure. Better understanding of the pathogenesis of IgAN and the related genetic, immunological, and cellular susceptibility factors are needed to enable the development of effective disease-specific therapy. This book brings together international experts to provide clinical and experimental studies and reviews with an emphasis on early diagnosis, prognosis, disease pathogenesis, determination of disease activity, and new strategies for treatment for IgAN.


Book
Nutra-Cosmeceuticals from Algae for Health and Wellness
Authors: --- ---
Year: 2022 Publisher: Basel MDPI - Multidisciplinary Digital Publishing Institute

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Microalgae and seaweeds are a renewable source of potent bioactive ingredients with confirmed positive impacts on health and wellness. The interest in—and awareness of—the need to improve quality of life and well-being has led to a greater consumption of nutraceuticals, as well as the use of cosmeceuticals for “well-aging”. In this context, algae and microalgae are currently gaining immense popularity within the functional food, nutraceutical, and cosmeceutical industries. Recent advances in the characterization and evaluation of the biological properties of the whole material, fractions, or isolated compounds of algae and microalgae enable their use as ingredients for the development of novel nutraceutical and cosmeceutical products.

Galactose regulon of yeast : from genetics to systems biology
Author:
ISBN: 1281241865 9786611241865 3540740155 3540740147 3642093302 Year: 2008 Publisher: Berlin : Springer,

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The galactose regulon of yeast is one of the best studied regulons. It is an ideal paradigm for demonstrating fundamental and evolving concepts in biology and is used in this book as a model system to explain various facets of conventional and modern biology. The book starts with a brief historical overview on yeast research, i.e. early observations in enzyme adaptation, classical genetics, formulating hypotheses based on genetic inference. This is followed by molecular genetics of the galactose regulon, isolation of genes and testing of the hypotheses. The power of mutational analysis in deciphering molecular mechanisms is conveyed. Further, contemporary topics such as genomics, evolution, single cell analysis of transcriptional switching, binary and graded responses, biological consequences of feed back regulation in genetic circuits, and stochasticity are addressed.


Book
Marine Anti-inflammatory and Antioxidant Agents 2021
Authors: ---
Year: 2022 Publisher: Basel MDPI - Multidisciplinary Digital Publishing Institute

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Abstract

The Special Issue “Marine Anti-Inflammatory and Antioxidants Agents 2021” collected the latest research, both in vitro and in vivo, on natural compounds from a variety of deep-sea organisms with anti-inflammatory and/or antioxidant properties as potential candidates for new drug discovery, and more generally for the field of marine biotechnology. The research presented here discusses the potential benefits of certain peptides and proteins derived from oysters, blue mussels, and cyanobacteria, as well as the carotenoid pigment astaxanthin, which is found in a variety of marine organisms. This Special Issue has carved out an important space for crude extracts from marine products, such as microalgae and green algae, highlighting their potential benefits to human health. Finally, the Special Issue includes a review of the benefits of some natural compounds derived from the algal biome against inflammatory bowel diseases, as well as a research article identifying the presence of the OvoA gene in arthropods for the first time. Through an excursus of high-quality research, this Special Issue provides the entire scientific community with new tools and insights to catch a molecular treasure for human health from the sea.


Book
Sulfur-Containing Marine Bioactives
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Year: 2021 Publisher: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute

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Sulfur is an essential element for all living organisms and is required by algae, plants, fungi, animals, and humans for growth and development. It is present in a variety of biomolecules involved in many biological functions, including the maintenance of cell redox homeostasis, defense, and detoxifying processes. The alteration of sulfur compound metabolism may lead to human diseases as well as to plant and animal pathologies. The marine environment, which is characterized by a high biodiversity of species and a great chemical diversity, represents a great potential source of bioactive sulfur molecules. A broad range of biologically active sulfur compounds with unique structures and pharmacological properties have been reported to occur in marine organisms, from amino acids to different sulfated derivatives. Great attention is also focused on sulfur metabolites in the marine microbial world in relation to the global sulfur cycle. The aim of this Special Issue is to present existing knowledge and recent studies on sulfur-containing marine bioactive compounds in different biological systems. Attention is also focused on metabolites active at the ecological level.


Book
Soft, Biological and Composite Nanomaterials
Authors: ---
Year: 2020 Publisher: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute

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The progress in the area of nanotechnology has opened the door for the fabrication of soft, biological, and composite nanomaterials for targeted applications. Nanomaterials are known to enhance the properties and functionality of composite materials several fold. The properties for the desired applications can often be achieved by the addition of small amounts of nanomaterials into soft materials such as polymers, gels, and biomaterials. This book condenses investigations by scientific groups from highly diverse research fields, which will be beneficial for the wider scientific community.


Book
Molecular Mechanisms of Sensorineural Hearing Loss and Development of Inner Ear Therapeutics
Author:
Year: 2021 Publisher: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute

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The sense of hearing is vulnerable to environmental challenges, such as exposure to noise. More than 1.5 billion people experience some decline in hearing ability during their lifetime, of whom at least 430 million will be affected by disabling hearing loss. If not identified and addressed in a timely way, hearing loss can severely reduce the quality of life at various stages. Some causes of hearing loss can be prevented, for example from occupational or leisure noise. The World Health Organization estimates that more than 1 billion young people put themselves at risk of permanent hearing loss by listening to loud music over long periods of time. Mitigating such risks through public health action is essential to reduce the impact of hearing loss in the community. The etiology of sensorineural hearing loss is complex and multifactorial, arising from congenital and acquired causes. This book highlights the diverse range of approaches to sensorineural hearing loss, from designing new animal models of age-related hearing loss, to the use of microRNAs as biomarkers of cochlear injury and drug repurposing for the therapy of age-related and noise-induced hearing loss. Further investigation into the underlying molecular mechanisms of sensorineural hearing loss and the integration of the novel drug, cell, and gene therapy strategies into controlled clinical studies will permit significant advances in a field where there are currently many unmet needs.


Book
Cellular Oxidative Stress
Authors: ---
Year: 2021 Publisher: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute

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Abstract

This book collects 17 original research papers and 9 reviews that are part of the Special Issue “Cellular Oxidative Stress”, published in the journal Antioxidants. Oxidative stress on a cellular level affects the function of tissues and organs and may eventually lead to disease. Therefore, a precise understanding of how oxidative stress develops and can be counteracted is of utmost importance. The scope of the book is to emphasize the latest findings on the cellular targets of oxidative stress and the potential beneficial effect of antioxidants on human health.

Keywords

Medicine --- neuroinflammation --- clinical --- palmitoylethanolamide --- luteolin --- co-ultramicronization --- CNS pathology --- adaptive immune response --- cell homeostasis --- legumes --- liver --- hepatic steatosis --- lipid dyshomeostasis --- ROS --- traumatic brain injury --- palmitoylethanolamide (PEA) --- therapeutic strategies --- oxidative stress. --- RNA-Seq --- RPE --- Retinitis pigmentosa --- A2E --- diabetes --- glucose exposure --- oxidative stress --- Band 3 protein --- erythrocytes --- SO42− --- 4-hydroxy-2-nonenal --- 3-glutathionyl-4-hydroxynonanal --- astrocytoma cells --- soy --- soybeans --- soy foods --- antioxidants --- reactive oxygen species --- cardiovascular diseases --- cancer --- paw edema --- cashew nuts --- antioxidant --- inflammation --- polyphenols --- analgesic --- d-Galactose --- glycation --- SO42− uptake --- anion exchange --- diseases --- immune system --- NF-κB --- cigarette smoke extract --- nasal fibroblasts --- tissue inhibitor of metalloproteinases --- matrix metalloproteinase --- steroids --- Plasmodium falciparum --- syk kinase inhibitors --- artemisinin derivatives --- hemichromes --- cellular redox state --- mitochondrial function --- cisplatin nephrotoxicity --- acute pancreatitis --- obesity --- nitrosative stress --- PGC-1α --- microparticles --- vesiculation --- band 3 --- tert-Bytyl hydroperoxide t-BOOH --- nitric oxide donor --- calcium ionophore A23187 --- age-related macular degeneration (AMD) --- diet --- Substance-P --- adipose-derived stem cells --- paracrine factors --- epilepsy --- status epilepticus --- Trolox --- HeLa --- prooxidant --- AVD --- apoptosis --- neurodegeneration --- ncRNA --- miRNA --- tRNA fragments --- lncRNA --- circRNA --- preeclampsia --- hemostasis --- platelets --- coagulation --- fish --- mucosal immunity --- nasal immunity --- peroxide --- vitamin C --- NAC --- immunosenescence --- T cells --- vaccination --- aging --- microvascular permeability --- bradykinin --- interleukin 1β --- NADPH oxidase --- simvastatin --- molecular hydrogen --- autophagy --- matrix metalloproteinases --- reactive oxygen species (ROS) --- phytochemicals --- dietary chemicals --- natural compounds --- programmed cell death --- anoikis --- ferroptosis --- pyroptosis

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