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"Peritoneal metastases continue to be a potentially lethal manifestation of gastrointestinal and gynecologic malignancy. In the past little if any treatments except systemic chemotherapy were available. Outcomes of treatment were poor and were routinely regarded as palliative. This dismal outlook has gradually changed as a result of two technical innovations: 1) Cytoreductive surgery with peritonectomy procedures and visceral resections and 2) Perioperative intraperitoneal and systemic chemotherapy. At this time approximately 2000 peritoneal oncology centers are active around the globe. With prevention and treatment of peritoneal metastases a reality the traditional role of the radiologist to characterize the malignancy is mandatory for knowledgeable management. We have discovered that the radiologic description of peritoneal metastases is challenging, to say the least. Progress has occurred. In our Pictorial Essays on Peritoneal Metastases Imaging: CT, MRI and PET-CT our radiologists have gathered together an abundance of information. Our book has established a role of the radiologist as an essential part of multidisciplinary management of a common and complex clinical problem. No longer is the radiologist's role only to determine if peritoneal metastases are absent versus present. The best technology or combinations of technology as CT, MRI or PET-CT must be selected. Not only a diagnosis of peritoneal metastases but extent and distribution of disease is required. The oncologist and surgeon need to know the likelihood of success with treatment. For primary cancer identification of patients at high risk for local-regional recurrence allows special treatments to be utilized before treatment failure occurs. If recurrent disease is suspect, the radiologist may interpret its causation and describe the interventions required to treat or suggest only palliation. The associated features of peritoneal metastases such as ascites or lymphadenopathy must be interpreted. The report must be complete with all information required by the clinician. Finally, the knowledgeable quantitation of concerning radiologic features can have profound prognostic implications. Our book not only verbally describes the images of peritoneal metastases, it shows them in carefully selected radiographs. The figures, figure legends and text allow the findings to be interpreted so they are clinically relevant. The images become a visible guide to construct a management plan. The radiologist's accurate description of peritoneal metastases is difficult at best, sometimes impossible, but comprehensively presented in this book. If one is interested in peritoneal metastases, the Pictorial Essays on Peritoneal Metastases Imaging: CT, MRI and PET-CT is a required addition to the personal library"--
Peritoneum --- Cancer --- Imaging.
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Liver --- Peritonitis. --- Peritoneum --- Diseases. --- Diseases
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Intraperitoneal Cancer Therapy investigates intraperitoneal chemotherapy in a variety of complex and interesting ways. The volume details major clinical trails to date, including immunotherapy, hyperthermic treatment of colo-rectal and ovarian cancers. Authors also examine regional approaches to therapy, systemic therapy, and the use of carboplatin and paclitaxel as the standard treatment for women with stages III and IV ovarian cancer. Other chapters also investigate techniques and procedures in treatment, as well as the future direction of both normothermic and hyperthermic intraperitoneal chemotherapy.
Peritoneum --- Cancer --- Treatment --- Abdomen --- Membranes (Biology)
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The mesothelium is composed by a single layer of mesothelial cells that vest the serosal cavities (pleural, peritoneal and pericardial) and internal organs of the body. The mesothelial cells have a mixed phenotype of epithelial cells and fibroblasts rendering them remarkable plasticity. Besides providing a slippery surface for the frictionless movement of internal organs, the mesothelium participates in a wide range of physiological and pathophysiological processes. Some of its functions include lung development, trans-cellular and para-cellular transport of ions and water, secretion of glycoproteins (mainly hyaluronan), secretion of cytokines and growth factors, wound healing, response to inflammatory stimuli and induction of inflammation, mesothelial to mesenchymal transition and formation of tunneling nanotubes. Many of these functions are pivotal to physiological conditions such as respiratory development, maintenance of steady volume of serosal fluids and serosal permeability, cell-to-cell communication, re-mesotheliazation of serosal membranes after mechanical (e.g. by asbestos or nanoparticles) or inflammatory injury and participation in immune responses. Deviation from the physiological threshold of these functions results in the development of serosal effusions, induction of serosal and lung fibrosis, induction of mesothelial tumorigenesis, leading thus to devastating pathologies. Treatment of pathologies like mesothelioma, pleural and peritoneal fibrosis (in cases of patients under Peritoneal Dialysis) or lung fibrosis still pose a great challenge for researchers.
Mesothelium --- Serosal Membranes --- Physiology --- Pleura --- Peritoneum --- Pericardium
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This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact
peritoneal dialysis --- mesothelial cells --- renal replacement therapy --- peritonitis --- peritoneum
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Pleura. --- Peritoneum. --- Medicine --- Clinical Medicine --- Parametrium --- Parietal Peritoneum --- Peritoneum, Parietal --- Peritoneum, Visceral --- Visceral Peritoneum --- Parametriums --- Parietal Pleura --- Visceral Pleura --- Pleura, Parietal --- Pleura, Visceral --- Pleurisy --- Clinical medicine --- Clinical medicine. --- Medicine. --- Health Workforce --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Medical sciences --- Pathology --- Physicians --- Medicine, Clinical --- pleural effisions --- peritoneum --- cytology --- laparoscopy --- cancer therapy --- radio therapy --- Pleura --- Peritoneum --- Médecine --- Médecine clinique --- Plèvre. --- Péritoine. --- Abdomen --- Membranes (Biology) --- Chest --- Lungs
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Peritoneum. --- Peritoneal Cavity. --- Drug Delivery Systems --- Nanoparticle Drug Delivery System. --- Drug Delivery Systems.
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The term ""ascites"" is from the Greek word askites meaning ""baglike."" Although most commonly due to cirrhosis, severe liver disease or metastatic cancer, its presence can be a sign of other significant medical problems, such as Budd-Chiari syndrome. Diagnosis of the cause is usually done with blood tests, an ultrasound scan of the abdomen, and direct removal of the fluid by a needle or paracentesis (which may also be therapeutic). Treatment using medications (diuretics), external drainage, or other treatments is clearly defined. In this book, the authors describe the physiopathology of the diverse causes of ascites,the types of treatments recommended, the recent advances achieved, the complications and the prognosis of the different clinical situations that doctors must face.
Ascites. --- Abdominal dropsy --- Dropsy, Abdominal --- Dropsy, Peritoneal --- Hydroperitoneum --- Hydroperitonia --- Hydrops abdominis --- Peritoneal dropsy --- Pathology --- Peritoneum --- Diseases --- Medicine --- Hepatology --- Gastroenterology --- Health Sciences
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Diseases --- Ascites --- Abdominal dropsy --- Dropsy, Abdominal --- Dropsy, Peritoneal --- Hydroperitoneum --- Hydroperitonia --- Hydrops abdominis --- Peritoneal dropsy --- Pathology --- Peritoneum --- Aetiology --- Etiology --- Causes and theories of causation. --- Treatment.
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This book is unique in addressing the management and complications of PD-related peritonitis to reduce morbidity and mortality. It addresses the measures to prevent peritonitis, types of tools used for diagnosis, including molecular techniques, the focus of microbiologists for educating peers, catheter-related issues such as catheter care, exit site, and tunnel infection, catheter removal, reimplantation techniques, nurses' role, nutrition aspects, surgical methods and pediatric peritoneal dialysis, peritonitis with its uniqueness in detail. Each chapter starts with a case scenario and pictures related to the branch by the contributors' experience. This book is helpful for physicians, nurses, technicians, microbiologists, ID trainees and consultants, nephrology trainees, nephrologists, and surgeons involved in PD care.
Peritoneal dialysis --- Peritonitis. --- Complications. --- Peritoneum --- Lavage, Peritoneal --- Peritoneal lavage --- Hemodialysis --- Diseases --- Nephrology. --- Gastroenterology. --- Internal medicine. --- Internal Medicine. --- Medicine, Internal --- Medicine --- Internal medicine --- Digestive organs --- Kidneys
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