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Intracellular Ca2+ signaling is witnessing an amazing resurgence of interest. In addition to traditional Ca2+ aficionados, an astonishing (and growing) number of colleagues from all around the world have started to devote a large part of their research to gain insights into the role of Ca2+ signaling in health and disease. This is why calcium ions interact with virtually every signal transduction pathway not only in mammalian cells, but also across the phylogenetic tree, thereby, driving or modulating most, if not all, cellular functions, ranging from fertilization to apoptosis, passing through learning and memory, cardiac contractility, and immune response. This book gathers a collection of original research articles and reviews by a number of renowned experts who aim to present the state of the art of many pathophysiological aspects of intracellular Ca2+ signaling, such as embryonic development, immune response, extracellular Ca2+ signaling, neoplastic transformation, muscle hypertrophy, pulmonary inflammation, and P2X receptor gating.

STIM --- intracellular Ca2+ oscillations --- Ca2+ signaling --- 5-trisphosphate receptors --- neurovascular coupling --- cardiac contractility --- inositol-1 --- SERCA --- NMDA receptors --- calcineurin --- Orai --- P2X receptors --- Ca2+-Sensing Receptor --- 4 --- immune response --- cancer --- Ca2+-activated K+ channels --- muscle hypertrophy --- ryanodine receptors

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The second edition of this key resource provides a broad and fundamental overview of basic cardiovascular (CV) hemodynamic principles with a focus on clinical assessment of CV physiology. Extensively updated, the book includes new coverage on noninvasive hemodynamic assessment and the effects of selected interventions on CV hemodynamics. It provides an introduction to the basic concepts such as preload, afterload, myocardial contractility, and cardiac output. Subsequent chapters examine the effects of interventions such as vasodilators, beta blockers, pressor agents, inotropes, and different forms of invasive circulatory support. The book also focuses on various methods of hemodynamic evaluation including echocardiography, CT/MRI, noninvasive hemodynamic assessment, and cardiac catheterization. The book concludes with a discussion of proper diagnosis, evaluation, and management of patients using hemodynamic data on a variety of specific disease states. An invaluable contribution to the Contemporary Cardiology Series, the Second Edition of Cardiovascular Hemodynamics: An Introductory Guide is an essential resource for physicians, residents, fellows, medical students, and researchers in cardiology, emergency medicine, critical care, and internal medicine.

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Viscera --- Medicine, Chinese. --- Pulse --- Viscera. --- Medicine, Chinese Traditional. --- Pulse. --- Medicine, Chinese --- Body Regions --- Medicine, East Asian Traditional --- Physical Examination --- Hemodynamics --- Heart Function Tests --- Anatomy --- Medicine, Traditional --- Diagnostic Techniques, Cardiovascular --- Cardiovascular Physiological Phenomena --- Diagnostic Techniques and Procedures --- Complementary Therapies --- Diagnosis --- Culture --- Circulatory and Respiratory Physiological Phenomena --- Therapeutics --- Anthropology, Cultural --- Phenomena and Processes --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Anthropology --- Social Sciences --- Anthropology, Education, Sociology and Social Phenomena --- Medicine, Chinese Traditional --- Medicine --- Health & Biological Sciences --- Internal Medicine --- Chinese Traditional Medicine --- Traditional Chinese Medicine --- Traditional Tongue Assessment --- Traditional Tongue Diagnosis --- Chinese 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