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The term "RNA editing" describes a diverse set of biochemical processes whereby genetic information is modulated on a post-transcriptional level i.e. on the level of ribonucleic acids (RNA). RNA editing has been demonstrated in viruses, protozoan organisms, in plants and in mammals and in many cases it has been identified as a key step in the regulation of gene expression. This book dedicates a chapter to each of the main types of RNA editing. All sections are written by experts in the various research areas and a specific focus is put on the correlation between RNA structure and function, as well as on the complex cellular machineries that catalyze the different editing reactions. This leads to a "state of the art" compendium of our current knowledge on RNA editing.
RNA editing. --- Editing, RNA --- Messenger RNA editing --- mRNA editing --- Genetic regulation --- RNA Editing. --- ARN --- Edition --- EPUB-LIV-FT LIVBIOLO SPRINGER-B
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This publication summarizes the current status of our understanding of RNA, with particular emphasis on the chemistry of this key biological molecule. The various RNAs covered are messenger RNA, ribosomal RNA, transfer RNA and RNA enzymes (ribozymes). The different chapters detail biophysical and chemical methods to investigate RNA structure and function, the synthesis of native and modified RNAs and the latest advances in our understanding of the vast array of biological processes in which RNA is involved.
RNA. --- Biochemical genetics. --- Chemical genetics --- Biochemistry --- Molecular genetics --- Ribonucleic acid --- Ribose nucleic acid --- Nucleic acids --- Ribose --- RNA --- ARN --- ELSEVIER-B EPUB-LIV-FT
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Molecular biology --- RNA --- ARN --- periodicals --- Periodicals --- Périodiques --- Molecular Biology --- RNA. --- ARN. --- Health Sciences --- Life Sciences --- Physiology --- Genetics --- Ribonucleic acid --- Ribose nucleic acid --- Gene Products, RNA --- Non-Polyadenylated RNA --- RNA, Non-Polyadenylated --- Ribonucleic Acid --- Acid, Ribonucleic --- Non Polyadenylated RNA --- RNA Gene Products --- RNA, Non Polyadenylated --- Biopolymers --- Nucleic acids --- Ribose --- ר.נ.א. (חמצת גרעין)
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The large potential of RNA sequencing and other ""omics"" techniques has contributed to the production of a huge amount of data pursuing to answer many different questions that surround the science's great unknowns. This book presents an overview about powerful and cost-efficient methods for a comprehensive analysis of RNA-Seq data, introducing and revising advanced concepts in data analysis using the most current algorithms. A holistic view about the entire context where transcriptome is inserted is also discussed here encompassing biological areas with remarkable technological advances in the study of systems biology, from microorganisms to precision medicine.
Genetics. --- RNA. --- Access Research Network. --- Ribonucleic acid --- Ribose nucleic acid --- Nucleic acids --- Ribose --- Biology --- Embryology --- Mendel's law --- Adaptation (Biology) --- Breeding --- Chromosomes --- Heredity --- Mutation (Biology) --- Variation (Biology) --- ARN --- Life Sciences --- Microbiology --- Genetics and Molecular Biology --- Biochemistry --- Microbial Genetics
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This laboratory guide represents a growing collection of tried, tested and optimized laboratory protocols for the isolation and characterization of eukaryotic RNA, with lesser emphasis on the characterization of prokaryotic transcripts. Collectively the chapters work together to embellish the RNA story, each presenting clear take-home lessons, liberally incorporating flow charts, tables and graphs to facilitate learning and assist in the planning and implementation phases of a project.RNA Methodologies, 3rd edition includes approximately 30% new material, including chapters on
RNA --- Molecular Biology --- ARN --- isolation & purification --- methods --- physiology --- Analysis --- Laboratory manuals. --- Analyse --- Manuels de laboratoire --- ELSEVIER-B EPUB-LIV-FT --- Nucleic acids --- Polynucleotides --- Biomolecules --- Ribonucleic acid --- Ribose nucleic acid --- Ribose --- Biochemistry.
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Responding to the immense changes due to recent development in research, Genomes is the first in a generation of molecular genetics books which combine standard molecular biology with more contemporary genomics. This book focuses on genome organization, expression, replication, and evolution, and includes a description of applications for molecular ecology and anthropology, reflecting the impact of genome biology on other fields of study.
Molecular biology --- genomen (geneeskunde) --- Genomes. --- Génomes --- genomes --- Carte génétique --- genetic maps --- Génie génétique --- genetic engineering --- Protéine de liaison --- Binding proteins --- ADN --- DNA --- ARN --- RNA --- Réplication --- replication --- Biologie moléculaire --- Biochimie --- biochemistry --- Phylogénie --- Phylogeny --- 575.113 --- #ABIB:aimm --- Genetica --- Genomen --- Gene. Genetic apparatus. Genome --- 575.113 Gene. Genetic apparatus. Genome --- Génomes --- moleculaire biologie --- DNA. --- RNA. --- replication. --- Molecular Biology. --- Molecular Biology --- Genes --- Genome, human --- Proteome
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extracellular RNA --- disease biomarkers --- RNA --- RNA. --- Ribonucleic acid --- Ribose nucleic acid --- Nucleic acids --- Ribose --- Gene Products, RNA --- Non-Polyadenylated RNA --- RNA, Non-Polyadenylated --- Ribonucleic Acid --- Acid, Ribonucleic --- Non Polyadenylated RNA --- RNA Gene Products --- RNA, Non Polyadenylated --- Biopolymers --- extracellular rna --- Biology --- Pharmacology. Therapy --- ARN
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Bones --- Non-coding RNA. --- Diseases --- Genetic aspects. --- fRNA --- Functional RNA --- ncRNA --- nmRNA --- Non-messenger RNA --- Non-translated RNA --- Noncoding RNA --- Nontranslated RNA --- Small non-messenger RNA --- Small RNA --- snmRNA --- sRNA --- Untranslated RNA --- RNA --- Teixit ossi --- Ossos (Teixits) --- Teixits ossis --- Esquelet --- Teixit connectiu --- Calcificació --- Ossos --- Àcid ribonucleic --- ARN --- Àcids nucleics --- Micro RNAs
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This open access volume gathers a variety of models, delivery systems, and approaches that can be used to assess RNA technology for exploiting antisense as a therapeutic intervention. Beginning with a section on the design of antisense technology and their delivery, the book continues by covering model systems developed to evaluate efficacy, both in vivo and in vitro, as well as methods to evaluate preclinically the toxicity associated with these new potential drugs, and intellectual property considerations. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Antisense RNA Design, Delivery, and Analysis provides basic knowledge and a large collection of methods to facilitate the work of newcomers to this vibrant and expanding field. This book was conceived thanks to the network DARTER (Delivery of Antisense RNA Therapeutics). DARTER is funded by the EU Cooperation of Science and Technology (COST), which aims to enhance interaction and collaborations between researchers in Europe and other countries.
Therapeutics. --- Biomaterials. --- Nucleic acids. --- Nucleic Acid. --- Polynucleotides --- Biomolecules --- Medical treatment --- Therapy --- Treatment of diseases --- Treatments for diseases --- Clinical medicine --- RNA therapeutics --- Antisense technology --- Therapeutic design --- Oligonucleotides --- Model systems --- Oligonucleotide-mediated toxicology --- Open Access --- Àcids nuclèics --- RNA --- Teràpia genètica --- Teràpia gènica --- Terapèutica genètica --- Enginyeria genètica --- Terapèutica --- Àcid ribonucleic --- ARN --- Àcids nucleics --- Micro RNAs --- Biomolècules --- ADN --- Nucleoproteïnes --- Transformació genètica --- Àcids nucleics.
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This text provides a broad range of up-to-date techniques presented in a functional framework. It provides the necessary background and strategies for approaching any RNA investigation, as well as detailed protocols and extensive tips and troubleshooting information.
RNA --- ARN --- Analysis --- Laboratory manuals --- Analyse --- Manuels de laboratoire --- Genetic techniques --- Genetic Techniques --- Gene Products, RNA --- Non-Polyadenylated RNA --- RNA, Non-Polyadenylated --- Ribonucleic Acid --- Acid, Ribonucleic --- Non Polyadenylated RNA --- RNA Gene Products --- RNA, Non Polyadenylated --- Biopolymers --- Genetic Technic --- Genetic Technics --- Genetic Technique --- Technic, Genetic --- Technics, Genetic --- Technique, Genetic --- Techniques, Genetic --- Genetics --- Genetic Counseling --- Genetic Phenomena --- Ribonucleic acid --- Ribose nucleic acid --- Nucleic acids --- Ribose --- methods --- Genetic Techniques. --- Rna
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