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Book
Scent from the Garden of Paradise
Author:
ISBN: 9789004336247 9004336249 9789004336315 9004336311 Year: 2017 Publisher: Leiden Boston

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Abstract

Since antiquity, musk has been a valued perfume and medicine. Because the musk deer only lives in Central Eurasia, people in other locations had to trade for its musk. For medieval Islamic civilization, musk became the most important of all aromatics. The musk trade thus illuminates the nature of medieval Asian trade and musk's cultural effects on the Islamic world. Scent from the Garden of Paradise: Musk and the Medieval Islamic World examines the history of musk from its origins in Asia to its uses in the medieval Middle East, surveys the Islamic literature on musk, and discusses the roles of musk in perfumery and medicine, as well as the symbolic importance of musk in Islam.


Book
Silver Nano/Microparticles : Modification and Applications 2.0
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Year: 2020 Publisher: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute

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Currently, nano/microparticles are widely used in various fields. Silver particles are one of the most vital of the various particles, due to their unique optical–physical–chemical properties. The developed materials have been proposed for use in various fields such as in biosensors, diagnostics, imaging, catalysts, solar cells, and as antibacterials. Their unique, size-dependent plasmonic properties render the particles superior in biomedical applications. This importance of silver materials led to the first edition of Silver Nano/Microparticles: Modification and Applications, which was successfully published last year with ten outstanding papers. This second edition of the Special Issue also provides original contributions detailing the synthesis, modification, and applications of silver materials. Eleven outstanding papers which describe examples of the most recent advances in silver nano/microparticles are included.


Book
Metal Free C-H Functionalization of Aromatics : Nucleophilic Displacement of Hydrogen
Authors: ---
ISBN: 3319070193 3319070185 Year: 2014 Publisher: Cham : Springer International Publishing : Imprint: Springer,

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The series Topics in Heterocyclic Chemistry presents critical reviews on present and future trends in the research of heterocyclic compounds. Overall the scope is to cover topics dealing with all areas within heterocyclic chemistry, both experimental and theoretical, of interest to the general heterocyclic chemistry community. The series consists of topic related volumes edited by renowned editors with contributions of experts in the field.


Book
Calixarene Complexes: Synthesis, Properties and Applications
Authors: ---
Year: 2021 Publisher: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute

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A growing interest has been devoted to the development of host systems for ionic and neutral species based on calixarenes. These cyclic oligomers show important host–guest properties, which has led to numerous applications in a broad range of fields, including organocatalysis, sensing, extraction and separation, and, more recently, biomedical applications. The relative ease of the functionalization of their upper and lower rims and the presence of a pre-organized cavity that is available in different sizes and conformations make calixarenes attractive building blocks for the construction of supramolecular assemblies. This book presents the most recent developments on the host–guest properties of calixarenes, as well as the new synthetic methods and applications.


Book
Iptycenes chemistry : from synthesis to applications
Authors: ---
ISBN: 3642328873 364243939X 3642328881 1283911426 Year: 2013 Publisher: Berlin ; Heidelberg : Springer,

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Iptycenes Chemistry: From Synthesis to Applications provides a comprehensive overview of the development of iptycene chemistry in the past seventy years. This book covers: (1) the basic nomenclature and general properties of iptycenes and their derivatives; (2) the synthesis and functionalization reactions of triptycenes, pentiptycenes, higher iptycenes, heterotriptycenes, and homotriptycenes; (3) the methods for the preparation of iptycene-based polymers with different types; and (4) the applications of iptycenes and their derivatives in molecular machines, materials science, host-guest chemistry, self-assembly, coordination chemistry, physical organic chemistry, medicinal chemistry, and so on. Consequently, such a book is not only helpful to researchers working in iptycene chemistry, but can also facilitate future research in wide areas.


Book
Polymers Enhancing Bioavailability in Drug Delivery
Authors: ---
ISBN: 3036556834 3036556842 Year: 2022 Publisher: Basel MDPI - Multidisciplinary Digital Publishing Institute

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Abstract

This Special Issue provides an update on the state of the art and current trends in polymeric drug-delivery systems specifically designed for improving drug bioavailability. The multiple contributions received further strengthen the role of polymers in modern drug delivery and targeting, illustrating the different approaches possible and unveiling what the future may bring.

Keywords

Medicine --- Pharmaceutical industries --- cystic fibrosis --- Pseudomonas aeruginosa --- liposomes --- efflux pump inhibitor --- PABN --- aminoglycosides --- macrolides --- poloxamer --- thiourea --- thiolation --- mucoadhesion --- drug release --- in vivo analysis --- in vitro dissolution studies --- S-propargyl-cysteine --- poly(lactic acid) --- endogenous hydrogen sulfide --- water-in-oil-in-water --- rheumatoid arthritis --- chitosan --- drug delivery --- drug absorption --- intestinal assimilation --- oral bioavailability --- nanoemulsions --- micelles --- SEDDS --- zeta potential --- sustained release --- albumin nanoparticle --- MPT0B291 --- high-pressure homogenizer --- histone deacetylase --- calix[8]arenes --- silibinin --- inclusion complexes --- PEGylation --- cytotoxicity --- oromucosal films --- sodium alginate --- nanoparticle drug carriers --- digoxin --- zein --- heart failure --- polymer–liposome complexes --- Pluronic®-poly(acrylic acid) --- Pluronic®-poly(N,N-dimethylaminoethyl methacrylate) --- stimuli-responsive --- intelligent drug delivery systems --- liposome --- polymer --- long circulation --- polymer–lipid conjugates --- targeting --- stimulus-responsive --- antibody --- affinity --- cyclodextrin --- protein therapeutics --- sustained drug delivery --- Nitric oxide --- hydrogel --- wound dressing --- chronic wounds --- glycyrrhetinic acid --- Soluplus® --- solid dispersions --- anti-inflammatory --- biosafety --- bioavailability --- n/a --- polymer-liposome complexes --- polymer-lipid conjugates


Book
Supramolecular Systems for Gene and Drug Delivery
Authors: --- ---
Year: 2022 Publisher: Basel MDPI - Multidisciplinary Digital Publishing Institute

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Dear Colleagues,Supramolecular systems (calixarenes, cyclodextrins, polymers, peptides, etc.) have attracted special attention due to their excellent therapeutic properties for biomedical applications such as gene and drug delivery. Numerous biomaterials-based supramolecular systems have been developed in the last decade for enhancing of biocompatibility and pharmacological activity. In particular, supramolecular nanomaterials are considered a hot research topic, because nanomedicine has become an interesting tool for the treatment of genetic diseases or cancer. Nevertheless, novel systems and their properties are being continuously studied, contributing to the development of efficient delivery systems.This Special Issue provides and highlights current progress in the use of the supramolecular systems for boosting gene and drug delivery. Preparation, characterization, and use of these systems, as well as the latest developments in this research field, are especially welcome.Authors are encorauged to submit original research articles and reviews in this promising research field.


Book
Advances in Cross-Coupling Reactions
Authors: ---
Year: 2020 Publisher: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute

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In this Special Issue, recent advances in cross-coupling reactions are presented in the form of original research articles, reviews, and short communications. These contributions cover different topics in this area, including novel coupling reactions, reaction conditions, synthetic alternatives, metal ligands, and applications for new pharmaceutical compounds and organic materials. In particular, the reviews deal with methodologies such as the synthesis of diarylketones through palladium catalysis and the most relevant examples of Suzuki–Miyaura and Buchwald–Hartwig coupling reactions in the synthesis of bioactive compounds. The synthetic utility of cross-coupling reactions for the synthesis of medium-size rings and the utility of Stille and Suzuki coupling reactions for the synthesis of new molecular machines based on sterically hindered anthracenyl trypticenyl units are also summarized. The original research articles present the synthesis of 2-alkynylpyrrols by inverse Sonogashira coupling and the synthesis of indoles under oxidative dearomative cross-dehydrogenative conditions. The efficient combination of iridium-catalyzed C–H borylation of aryl halides with the Sonogashira coupling and a sequential iridium-catalyzed borylation of NH-free pyrroles followed by a Suzuki–Miyaura reaction are included. The synthesis of aryl propionic acids, a common structural motif in medicinal chemistry, and the synthesis of new organic dyes are also covered.

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