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Book
Nutrients Intake and Hypertension
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ISBN: 3039286633 3039286625 Year: 2020 Publisher: MDPI - Multidisciplinary Digital Publishing Institute

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Abstract

Hypertension is a major health problem worldwide, increasing cardiovascular (CV) risk and mortality. Together with pharmacological treatments, non-pharmacological approaches, such as nutrient intake modifications, play an important role in optimizing treatment. A link has been demonstrated between hypertension and body weight as well as dietary habits. The aim of this Special Issue is to improve the understanding of the relationships between some nutrients and hypertension, and of the effects of different dietary approaches on hypertension regulation from different points of view.


Book
New Trends in Neuromechanics and Motor Rehabilitation
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ISBN: 3036551786 3036551778 Year: 2022 Publisher: MDPI - Multidisciplinary Digital Publishing Institute

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Neuromechanics has been used to identify optimal rehabilitation protocols that successfully improve motor deficits in various populations, such as elderly people and individuals with neurological diseases (e.g., stroke, Parkinson’s disease, and essential tremor). By investigating structural and functional changes in the central and peripheral nervous systems based on neuromechanical theories and findings, we can expand our knowledge regarding underlying neurophysiological mechanisms and specific motor impairment patterns before and after therapies to further develop new training programs (e.g., non-invasive brain stimulation). Thus, the aim of this Special Issue is to present the main contributions of researchers and rehabilitation specialists in biomechanics, motor control, neurophysiology, neuroscience, and rehabilitation science. The current collection provides new neuromechanical approaches addressing theoretical, methodological, and practical topics for facilitating motor recovery progress.


Book
The Prevention and Treatment of Atherosclerosis
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Year: 2022 Publisher: Basel MDPI - Multidisciplinary Digital Publishing Institute

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This special issue of JCM ‘The Prevention and Treatment of Atherosclerosis’ will walk the Readers across novel diagnostic achievements in atherosclerosis and contemporary actions towards optimizing therapy.Everything begins with diagnosis. Accurate diagnostic tools and tests are of utmost importance. Contemporary research on microparticles, non-coding RNAs, proteomic characterization, …, offers detailed molecular characteristics of athero-thrombosis.Prevention is equally important as treatment. The impact of eating habits in prophylaxis of many pathologies, including cardiovascular disease has been documented.Then new pharmacological agents. Managing hypercholesterolemia with PCSK9 inhibitors, shown great potential in efficient lipid lowering to achieve LDL-C treatment goals, as well as reduction in cardiovascular mortality and morbidity.However, therapeutic goals accomplishment requires supervision. Arising number of data support that cardiovascular risk prediction can be improved with imaging modalities displaying atheroma: carotid plaque ultrasonography, coronary calcium score, intravascular ultrasonography, and optical coherent tomography or many others.As atherosclerosis is a progressive disease, it comes the time for more radical management, including endovascular and surgical intervention. There is field for new stent and equipment technologies, new surgical and endovascular techniques, supervision of endovascular procedures with IVUS, OCT, functional flow assessment or cell therapy.From diagnosis to risk stratification, elaborated prevention models, finally to modern and optimized therapeutic intervention.


Book
Comorbidities in Chronic Kidney Disease (CKD)
Authors: ---
Year: 2021 Publisher: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute

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With a mean worldwide prevalence of 13%, chronic kidney disease imposes a massive health burden on our society. In addition to reduced kidney function, patients with chronic kidney disease increasingly suffer from cardiovascular diseases affecting the heart and vasculature. Cardiovascular diseases account for around half of the deaths of patients with advanced chronic kidney disease. However, therapeutic options are highly insufficient. The pathological mechanisms that underlie increased cardiovascular risk in patients with chronic kidney disease remain largely unknown. This Special Issue provides insights into comorbidities in CKD patients, mainly focused on increased cardiovascular risk, and summarizes current knowledge of underlying pathophysiological mechanisms.


Book
The Effect of Diet on Cardiovascular Disease, Heart Disease and Blood Vessels
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Year: 2022 Publisher: MDPI - Multidisciplinary Digital Publishing Institute

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Cardiovascular disease (CVD), including coronary artery disease, heart disease, arrhythmias, and other types of vascular diseases, is one of the leading causes of death around the world. It is estimated that approximately half of the variabilities of CVD appear to be attributed to genetics. Therefore, the other half of them have been attributed to acquired factors, including diet. It is of note that even a genetic predisposition to CVD can be canceled out by a healthy lifestyle. In this regard, it is important to acknowledge that acquired factors, including diet, are causally associated with CVD. Based on these facts, important papers are presented in this Special Issue entitled “The Effect of Diet on Cardiovascular Disease, Heart Disease, and Blood Vessels”.


Book
Wood Properties and Processing
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ISBN: 3039288229 3039288210 Year: 2020 Publisher: MDPI - Multidisciplinary Digital Publishing Institute

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Wood-based materials are CO2-neutral, renewable, and considered to be environmentally friendly. The huge variety of wood species and wood-based composites allows a wide scope of creative and esthetic alternatives to materials with higher environmental impacts during production, use and disposal. Quality of wood is influenced by the genetic and environmental factors. One of the emerging uses of wood are building and construction applications. Modern building and construction practices would not be possible without use of wood or wood-based composites. The use of composites enables using wood of lower quality for the production of materials with engineered properties for specific target applications. Even more, the utilization of such reinforcing particles as carbon nanotubes and nanocellulose enables development of a new generation of composites with even better properties. The positive aspect of decomposability of waste wood can turn into the opposite when wood or wood-based materials are exposed to weathering, moisture oscillations, different discolorations, and degrading organisms. Protective measures are therefore unavoidable for many outdoor applications. Resistance of wood against different aging factors is always a combined effect of toxic or inhibiting ingredients on the one hand, and of structural, anatomical, or chemical ways of excluding moisture on the other.

Keywords

neural network --- Pinus massoniana Lamb. --- intra-ring variation --- relative humidity --- ultimate state --- nondestructive assessment --- machinability --- stiffness --- wood based composites --- bamboo --- poplar seedlings --- thinning --- blue staining fungi --- tropical woods --- compression --- bending stiffness --- wooden windows --- ultrasonic wave velocity measurement --- glued lamella --- three-point bending --- wood properties --- technological and product innovations --- structural changes --- non-destructive testing --- hardwoods --- brittleness --- green larch --- root-collar diameter --- FTIR --- material preference --- cooling tower --- tensile modulus --- strength grading --- immigrants --- weight of a user --- density --- flexible chair --- predictive performance --- heat treatment --- modulus of elasticity --- orthotropic --- acoustic resonance --- building material --- CIEL*a*b* system --- deflection at the modulus of rupture --- marketing --- bamboo grid packing --- fungi --- minimal curve radius --- European hardwoods --- cyclic loading --- chemical composition --- laminated wood --- volume yield --- tensile strength --- artificial weathering --- glulam --- dynamic modulus of elasticity --- colour changes --- modulus of elasticity (MOE) --- coefficient of wood bendability --- urban housing --- Resistance to Impact Milling (RIM) --- nondestructive testing --- Coniophora puteana --- roughness --- brown rot --- wood --- phenol formaldehyde resin --- wood-processing industry performance --- elemental composition --- natural weathering --- longitudinal stress wave velocity --- mechanical properties --- aluminium reinforcements --- chemical changes --- colour change --- High-Energy Multiple Impact (HEMI)–test --- plantation timber --- fiber-managed hardwoods --- cooling packing --- wood mechanical properties --- flexural rigidity --- moisture content --- ultrasonic speed --- color --- elastic constants --- Douglas-fir --- mixed-effects hierarchical linear models --- wood impregnation --- dynamic strength --- microfibril angle --- silviculture --- low quality round wood --- Eucalyptus --- hybrid beams --- end-product-based fiber attribute determinates --- high frequency drying --- infrared spectroscopy --- building culture background --- lumber --- Euler-Bernoulli --- ultrasound --- cell-wall mechanics --- colour --- deflection at the limit of proportionality


Book
New Insights in the Genetics and Genomics of Adrenocortical Tumors and Pheochromocytomas
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Year: 2022 Publisher: Basel MDPI - Multidisciplinary Digital Publishing Institute

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This book includes 17 papers published in the Special Issue/Article Collection “New Insights in the Genetics and Genomics of adrenocortical tumors and pheochromocytomas” including an editorial, 10 research papers and six review articles. Adrenal tumors represent a hot topic in contemporary endocrine oncology. Significant advancements in the genetics of genomics of these tumors have been made in recent years, and these articles give a useful and comprehensive overview of these issues. Questions regarding molecular pathogenesis, diagnosis (biomarkers) and even treatment are discussed in the papers written by international leaders of the field. Manuscripts are focused on three main topics: i. primary aldosteronism (the most common cause of secondary endocrine hypertension), ii. adrenocortical cancer and iii. pheochromocytoma/paraganglioma, which are the tumors with the highest heritability in humans. The book is edited by Prof. Peter Igaz (Department of Endocrinology, Faculty of Medicine, Semmelweis University).

Keywords

pheochromocytoma --- paraganglioma --- genetics --- non-coding RNA --- malignancy --- biomarker --- treatment --- adaptive metabolism --- adrenal gland --- conn adenoma --- fatty acid metabolism --- ferroptosis --- hyperaldosteronism --- metabolic reprogramming --- β-oxidation --- PPARα --- tumor microenvironment --- Next Generation Sequencing --- hereditary cancer --- endocrine tumor syndrome --- KCNJ5 somatic mutation --- pulse wave velocity --- aldosterone-producing adenoma --- adrenalectomy --- propensity score matching --- arterial stiffness --- pheochromocytomas --- paragangliomas --- mutations --- susceptibility genes --- driver mutations --- hereditary --- germline --- somatic --- environment --- variants --- tumor suppressor genes --- metastatic --- RNAseq --- next generation sequencing --- adrenocortical carcinoma --- in silico analysis --- machine learning --- bioinformatic clustering --- biomarker prediction --- aldosterone producing adenoma --- ATP2B3 --- K416-F418delinsN mutation --- primary aldosteronism --- PPGL --- telomeres --- TERT --- ATRX --- NOP10 --- prognostic biomarker --- ALT --- phaeochromocytoma --- cancer --- mitochondrial complex II --- zebrafish --- therapy --- drug discovery --- redox balance pathway --- Vitamin C --- mitotane --- H295 strains --- microRNA --- aldosterone --- circulating --- adrenocortical --- transcriptomics --- epigenetics --- metabolomics --- epidemiology --- genetic analysis --- mortality --- surveillance --- TP53 R337H --- genetic testing --- adrenocortical tumor --- neonatal screening --- screening --- adenoma --- adrenal --- tissue --- artificial intelligence --- neural network --- n/a


Book
Inaugural Section Special Issue : Key Topics and Future Perspectives in Natural Hazards Research
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Year: 2021 Publisher: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute

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This book collects selected high-quality papers published in 2018–2020 to inaugurate the “Natural Hazards” Section of the Geosciences journal. The topics encompass: trends in publications at international level in the field of natural hazards research; the role of Big Data in natural disaster management; assessment of seismic risk through the understanding and quantification of its different components; climatic/hydro-meteorological hazards; and finally, the scientific analysis and disaster forensics of recent natural hazard events. The target audience includes not only specialists, but also graduate students who wish to approach the challenging, but also fascinating


Book
State of the Art Geo-Energy Technology in China
Authors: --- --- --- --- --- et al.
Year: 2022 Publisher: Basel MDPI - Multidisciplinary Digital Publishing Institute

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Dear colleagues, Geological energy has a long history in China. As early as 500 BC, China began to use coal as fuel. In the middle of the 19th century, China began to develop oil resources. After the foundation of new China, with the discovery of the Daqing oilfield, China's oil industry entered an era of great development. During the 21st century, with the development of drilling technology, the development of unconventional energy such as shale gas and shale oil has entered a new era. In recent years, the development of flammable ice has set off a wave of clean energy. With the carbon reduction plan proposed by the Chinese government, clean geo-energy has been granted unparalleled development space in the future. China's geo-energy development technology used to lag behind that of major developed countries for a long time, but after years of development, it has become the world's leading edge in some fields. Therefore, we specially set up this collection to collect China's advanced geo-energy exploitation technology and development trends, whilst providing some new directions for thinking about geo-energy development in China and even the world. This collection seeks to contribute to such topics through enhanced scientific and multidisciplinary knowledge.

Keywords

airflow reversal --- gas outburst --- mine ventilation system --- orthogonal experiment --- numerical simulation --- deep chamber --- asymmetric failure --- mechanical analysis --- control measures --- Yinggehai --- overpressure --- hydraulic fracture --- mudstone --- fluid pressure --- red sandstone --- pre-existing cracks --- creep behavior --- temperature --- long-term permeability --- partial saturation --- patchy saturation --- squirt flow --- P-wave velocity dispersion and attenuation --- anelasticity --- ultrasonic measurements --- heavy oil reservoirs --- cyclic steam stimulation --- conformance control --- extreme gradient boost (XGBoost) trees --- prediction model --- Dongsha Waters in the northern South China Sea margin --- velocity inversion --- mud volcano --- magma intrusion --- Mesozoic hydrocarbon --- tubing --- modal analysis --- fluid-structure interaction --- inlet pressure --- pipeline --- water hammer --- gas-liquid two-phase flow --- pressure --- velocity --- lattice Boltzmann method --- discrete element method --- sand production --- force chain network analysis --- seismic sedimentology --- sedimentary facies evolution --- peat accumulation regularity --- frequency–division amplitude fusion --- thin sand bodies --- stable crack propagation --- crack strain --- stress–strain curve --- model --- wing crack --- outburst coal --- primary coal --- structural parameters --- infrared spectrum --- XRD --- oil shale --- in situ conversion project --- biomarker --- pyrolysis process --- organic geochemistry


Book
Remote Sensing in Applied Geophysics
Authors: --- ---
Year: 2020 Publisher: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute

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The Special Issue is focused on recent and upcoming advances in the combined application of remote sensing and applied geophysics. Applied geophysics analyzes the distribution of physical properties in the subsurface for a wide range of geological, engineering, and environmental applications at different scales. Seismic, electrical, magnetic, and electromagnetic methods are among the most applied and well-established geophysical techniques. These methods share the advantages of being non-invasive and exploring wide areas of investigation with respect to conventional methods (e.g., drilling). Geophysical surveys are usually carried out deploying or moving the appropriate instrumentation directly on the ground surface. However, recent technological advances have resulting in the development of innovative acquisition systems becoming more typical of the remote sensing community (e.g., airborne surveys). While applied geophysics mainly focuses on the subsurface, typical remote sensing techniques have the ability to accurately image the Earth’s surface with high-resolution investigations carried out by means of terrestrial, airborne, or satellite-based platforms. The integration of surface and subsurface information is often crucial for several purposes, including the processing of geophysical data, the characterization and time-lapse monitoring of surface and near-surface targets, and the reconstruction of highly detailed and comprehensive 3D models of the investigated areas. Recent contributions showing the added value of surface reconstruction and/or monitoring in the processing, interpretation, and cross-comparison of geophysical techniques for archaeological, environmental, and engineering studies are collected in this book. Pioneering geophysical acquisitions by means of innovative remote systems are also presented.

Keywords

Alpine glaciers --- Belvedere Glacier --- ice thickness estimation --- ice bottom morphology and properties --- ground-penetrating radar (GPR) --- single-station passive seismic measurements --- horizontal-to-vertical spectral ratio (HVSR) --- archaeological prospection --- automated resistivity profiling ARP --- electrical resistivity survey --- multi-channel ground penetrating radar --- geophysical methods integration --- Chang’E-4 --- lunar penetrating radar (LPR) --- 3D velocity spectrum --- properties analysis --- remote sensing and GIS --- field geophysics --- groundwater potentiality --- West Qena --- Egypt --- mine collapse --- anthropogenic hazard --- seismology --- GNSS --- InSAR --- post-seismic deformation mechanism --- InSAR time series algorithm --- Kermanshah earthquake --- viscoelastic relaxation --- near-surface geophysics --- LiDAR --- magnetic gradiometry --- surface magnetic susceptibility --- electromagnetic induction --- Middle Woodland period --- Hopewell archaeology --- depth inversion --- sedimentary processes --- Autonomous Surface Vehicles (ASV) --- marine geophysics --- shallow water environments --- repeated 4D surveys --- NAIADI Project (New Autonomous/automatIc systems for the study AnD monitoring of aquatic envIronments) --- electrical resistivity tomography (ERT) --- frequency domain electromagnetic (FDEM) --- archaeology --- terramare --- bronze age --- elastic full waveform inversion --- acoustic-elastic coupled --- ocean bottom seismic --- multicomponent --- multiparameter --- ground penetrating radar (GPR) --- moisture content --- velocity analysis --- optimal gather --- passive seismic interferometry --- surface wave --- inversion --- shear-wave velocity --- ambient noise --- dispersion curve --- aerial archaeology --- landscape archaeology --- frequency-domain electromagnetic methods (FDEM) --- paleochannel --- Snow Eagle 601 --- aerogeophysics --- Princess Elizabeth Land --- ice-penetrating radar --- Antarctic ice sheet --- n/a --- Chang'E-4

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