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This book aims to provide readers with some of the current trends in mycology. Its chapters include discussions on the major invasive fungal diseases, host-pathogen interactions, relationships between fungal growth and the environment, the use of fungal species to control soil parasites, and the antifungal properties of thiosulfonates. The information herein covers topics in mycological research and will be of interest to students and researchers in all biological sciences.
Mycoses. --- Fungal diseases --- Fungal infections --- Fungous diseases --- Mycosis --- Mycotic diseases --- Mycotic infections --- Medical mycology --- Medicine --- Internal Medicine --- Infectious Diseases --- Health Sciences
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The history of mankind has been shaped by infections, more than by war and famine together. At the same time, however, the development of society has had an equally important effect on human diseases. The emergence of agriculture, urban societies and high population densities has been proven to be crucial for the spread of pathogens, and thus human action is currently the single most important driver of infectious epidemiology. Even today, where once major killers such as poliomyelitis have been eradicated, new pathogens are appearing as result of human activity. One such group of pathogens are the fungi, whose emergence is mainly due to modern medical practices. Fungal microorganisms, from yeasts colonizing the skin or mucosa, to molds from soil or water, are usually harmless in the context of normal host responses. However, the success of chemotherapy, as well as the AIDS pandemia, has led to immune deficiencies in a significant segment of the patient population, and the extensive use of intravenous catheters has provided a way of access for microorganisms which otherwise would find difficult to infect the host. As a result, a yeast such as Candida is now on the 4th place on the list of the most frequent sepsis agents, whereas infection with the mold Aspergillus is increasing in incidence and it is one of the most feared complications in patients with hematological malignancies.
Mycoses --- Pathogenic fungi. --- Immunological aspects. --- Fungi, Pathogenic --- Fungi --- Pathogenic microorganisms --- Medical mycology --- Fungal diseases --- Fungal infections --- Fungous diseases --- Mycosis --- Mycotic diseases --- Mycotic infections --- Immunology. --- Microbiology. --- Emerging infectious diseases. --- Medical Microbiology. --- Infectious Diseases. --- Emerging infections --- New infectious diseases --- Re-emerging infectious diseases --- Reemerging infectious diseases --- Communicable diseases --- Microbial biology --- Biology --- Microorganisms --- Immunobiology --- Life sciences --- Serology --- Medical microbiology. --- Infectious diseases.
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Mycoses. --- medical mycology --- Mycoses --- Fungal Diseases --- Fungal Infections --- Fungus Infections --- Fungus Diseases --- Disease, Fungal --- Disease, Fungus --- Diseases, Fungal --- Diseases, Fungus --- Fungal Disease --- Fungal Infection --- Fungus Disease --- Fungus Infection --- Infection, Fungal --- Infection, Fungus --- Infections, Fungal --- Infections, Fungus --- Fungal diseases --- Fungal infections --- Fungous diseases --- Mycosis --- Mycotic diseases --- Mycotic infections --- Medical mycology --- Biology --- Pathology
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Bacterial diseases --- Anti-infective agents --- Mycoses --- Chemotherapy --- Periodicals. --- Therapeutic use --- Therapeutic use. --- Chemotherapy. --- Antibacterial agents --- Fungal diseases --- Fungal infections --- Fungous diseases --- Mycosis --- Mycotic diseases --- Mycotic infections --- Medical mycology --- Antiinfective agents --- Antimicrobial agents --- Antimicrobial drugs --- Antimicrobials --- Drugs --- Bacterial infections --- Communicable diseases --- Medical bacteriology --- Pathogenic bacteria
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Fungal immunology, an expanding field of research, studies the interaction between fungi and the immune system. Modulated immunity as well as evasive mechanisms played by fungi all contribute to the chronicity and reoccurrence of fungal infections. Hypersensitivity to various fungal elements plays a major role in the pathogenesis of many diseases. This book will serve as a comprehensive review of all known immune mechanisms for common medically important fungal pathogens. Its novelty lies in the organization: Rather than chapters devoted to specific fungi, chapters are organized by organ system. All other texts in the field, which are now quite old, are arranged according to specific fungi. Organization by body system rather than fungi is important because one particular fungus can have a different effect on defense mechanisms in different parts of the body.
Mycoses --- Pathogenic fungi. --- Immunological aspects. --- Fungi, Pathogenic --- Fungi --- Pathogenic microorganisms --- Medical mycology --- Fungal diseases --- Fungal infections --- Fungous diseases --- Mycosis --- Mycotic diseases --- Mycotic infections --- Immunology. --- Microbiology. --- Emerging infectious diseases. --- Thoracic surgery. --- Medical Microbiology. --- Infectious Diseases. --- Thoracic Surgery. --- Microbial biology --- Biology --- Microorganisms --- Immunobiology --- Life sciences --- Serology --- Emerging infections --- New infectious diseases --- Re-emerging infectious diseases --- Reemerging infectious diseases --- Communicable diseases --- Thoracic surgery --- Thoracic surgeons --- Medical microbiology. --- Infectious diseases.
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Diagnosis and Treatment of Human Mycoses brings together globally-recognized mycoses experts to guide readers in the use of current knowledge in the field of medical mycology to manage those who suffer from fungal infections (mycoses). Often, diagnostic strategies and tests, including basic and directed culturing techniques, histopathology with standard and special stains, serological methods, and radiological studies all need to be considered and commonly combined to make the diagnosis of fungal infection. This volume first introduces and reviews these tools separately and then as they pertain to specific infections or groups of diseases. The volume consists of four parts. Parts I-III provide an overview of diagnostic and therapeutic tools, and part IV presents the human mycoses. Diagnosis and Treatment of Human Mycoses is meant to be a concise text that will provide the busy infectious disease, hematology–oncology, pulmonology, or critical care specialist a practical tool to diagnose and manage fungal infections. In addition, the depth of the material in the text will provide these and other medical specialists and trainees an excellent reference and learning resource.
Medical mycology. --- Mycoses --- Diagnosis. --- Treatment. --- Fungal diseases --- Fungal infections --- Fungous diseases --- Mycosis --- Mycotic diseases --- Mycotic infections --- Medical mycology --- Medical microbiology --- Mycology --- Pathogenic fungi --- Immunology. --- Emerging infectious diseases. --- Allergy. --- Internal medicine. --- Infectious Diseases. --- Allergology. --- Internal Medicine. --- Medicine, Internal --- Medicine --- Allergic diseases --- Allergies --- Hypersensitivity --- Hypersensitivity, Immediate --- Immediate allergy --- Immediate hypersensitivity --- Immunologic diseases --- Immunoglobulin E --- Emerging infections --- New infectious diseases --- Re-emerging infectious diseases --- Reemerging infectious diseases --- Communicable diseases --- Immunobiology --- Life sciences --- Serology --- Infectious diseases.
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Mycological studies of yeasts are entering a new phase, with the sequencing of multiple fungal genomes informing our understanding of their ability to cause disease and interact with the host. At the same time, the ongoing use of traditional methods in many clinical mycology laboratories continues to provide information for the diagnosis and treatment of patients. This volume reviews various aspects of pathogenic yeasts and what is known about their molecular and cellular biology and virulence, in addition to looking at clinical and laboratory findings. As each chapter is written by a leading expert in the field, this book summarizes in one volume much of the latest research on several pathogenic yeasts, including Candida, Cryptococcus, Malassezia and yeasts of emerging importance. The importance of laboratory diagnosis, antifungal susceptibility testing, antifungal resistance and yeast diseases in animals are reviewed.
Medical mycology. --- Pathogenic fungi. --- Yeast fungi. --- Yeast fungi --- Pathogenic fungi --- Medical mycology --- Bacterial Infections and Mycoses --- Fungi --- Yeasts --- Mycoses --- Eukaryota --- Diseases --- Organisms --- Biology --- Botany --- Microbiology & Immunology --- Fungi & Algae --- Health & Biological Sciences --- Earth & Environmental Sciences --- Candidiasis. --- Mycoses. --- Fungal diseases --- Fungal infections --- Fungous diseases --- Mycosis --- Mycotic diseases --- Mycotic infections --- Candida infection --- Candidosis --- Moniliasis --- Life sciences. --- Biodiversity. --- Microbiology. --- Life Sciences. --- Eukaryotic Microbiology. --- Biological diversification --- Biological diversity --- Biotic diversity --- Diversification, Biological --- Diversity, Biological --- Biocomplexity --- Ecological heterogeneity --- Numbers of species --- Microbial biology --- Microorganisms
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Medical mycology --- Fungi --- Mycoses --- Fungal diseases --- Fungal infections --- Fungous diseases --- Mycosis --- Mycotic diseases --- Mycotic infections --- Medical microbiology --- Mycology --- Pathogenic fungi --- Fungi. --- Mycology. --- Mycoses. --- Medical mycology. --- Fungal kingdom --- Fungus kingdom --- Funguses --- Mycobiota --- Mycota --- Cryptogams --- Fungal Diseases --- Fungal Infections --- Fungus Infections --- Fungus Diseases --- Disease, Fungal --- Disease, Fungus --- Diseases, Fungal --- Diseases, Fungus --- Fungal Disease --- Fungal Infection --- Fungus Disease --- Fungus Infection --- Infection, Fungal --- Infection, Fungus --- Infections, Fungal --- Infections, Fungus --- Infectious Disease Medicine --- Fungi, Filamentous --- Molds --- Filamentous Fungi --- Filamentous Fungus --- Fungus --- Fungus, Filamentous --- Mold --- Allergens --- Fungal Proteins --- Microbiology
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The currently available means of combating fungal infections are still weak and clumsy. The application of fungal genomics offers an unparalleled opportunity to develop novel antifungal drugs. Interestingly, several novel antifungal drug targets have already been identified and validated. However, it is too early to expect any novel antifungal drug as drug discovery programs are still in their infancy. In addition to classical and genomic approaches to drug discovery, traditional knowledge derived from natural products and phytomedicine can provide a multitude of alternative modes of combating fungal infection. This book comprises 20 chapters on various aspects pertaining to fungal diseases in human and animals, their reservoir, fungal pathogenesis, their management and recent advances in their treatment. Issues of antifungal drug toxicity, especially nephrotoxicity, are also discussed. The development of resistance in fungal pathogens, including multidrug resistance and its mechanism, is dealt with in two chapters. Diverse diagnostic approaches to fungal infections are also reviewed. The combinational drug strategies used in combating invasive fungal infections are addressed in detail. The management of pulmonary mycoses in stem cell transplantation is also given special focus. Novel antifungal drugs (synthetic and herbal), fungal vaccines, and metabolic pathways as drug targets are discussed in detail in three different chapters. Subsequently the roles of innate immunity, cytokine therapy and immunomodulators in the treatment of fungal infections are elaborated upon. As novel drug delivery systems have a great potential for modifying the pharmacokinetics of medications, the last chapter takes this fact into consideration in its examination of state-of-the-art delivery systems in controlling fungal infections.
Drug resistance, Fungal. --- Mycoses -- Treatment. --- Mycoses. --- Mycoses --- Bacterial Infections and Mycoses --- Anti-Infective Agents --- Drug Resistance, Microbial --- Drug Resistance, Fungal --- Antifungal Agents --- Microbiological Phenomena --- Drug Resistance --- Diseases --- Therapeutic Uses --- Pharmacologic Actions --- Pharmacological Phenomena --- Phenomena and Processes --- Physiological Phenomena --- Chemical Actions and Uses --- Chemicals and Drugs --- Medicine --- Biology --- Microbiology & Immunology --- Infectious Diseases --- Health & Biological Sciences --- Treatment --- Chemotherapy --- Fungal diseases --- Fungal infections --- Fungous diseases --- Mycosis --- Mycotic diseases --- Mycotic infections --- Medicine. --- Immunology. --- Medical microbiology. --- Pharmacology. --- Microbiology. --- Biomedicine. --- Medical Microbiology. --- Pharmacology/Toxicology. --- Medical mycology --- Toxicology. --- Chemicals --- Pharmacology --- Poisoning --- Poisons --- Immunobiology --- Life sciences --- Serology --- Microbial biology --- Microorganisms --- Toxicology --- Drug effects --- Medical pharmacology --- Medical sciences --- Drugs --- Pharmacy --- Physiological effect
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Pathogenic fungi --- Medical mycology --- Veterinary mycology --- Mycoses --- Mycoses. --- Medical mycology. --- Pathogenic fungi. --- Veterinary mycology. --- Champignon pathogène. --- Mycologie médicale. --- Mycose. --- Mykose --- Zeitschrift --- Online-Ressource --- Fungal Diseases --- Fungal Infections --- Fungus Infections --- Fungus Diseases --- Disease, Fungal --- Disease, Fungus --- Diseases, Fungal --- Diseases, Fungus --- Fungal Disease --- Fungal Infection --- Fungus Disease --- Fungus Infection --- Infection, Fungal --- Infection, Fungus --- Infections, Fungal --- Infections, Fungus --- Fungal diseases --- Fungal infections --- Fungous diseases --- Mycosis --- Mycotic diseases --- Mycotic infections --- Fungous diseases in animals --- Fungi, Pathogenic --- Netzpublikation --- Online-Publikation --- Computerdatei im Fernzugriff --- Online-Dokument --- On-line-Dokument --- On-line-Publikation --- Periodikum --- Zeitschriften --- Pilzinfektion --- Pilzkrankheit --- Mycose --- Health & Medicine (General) --- Mycology. --- Veterinary microbiology --- Medical microbiology --- Mycology --- Fungi --- Pathogenic microorganisms --- Elektronische Publikation --- Presse --- Fortlaufendes Sammelwerk --- Infektionskrankheit --- Pilzbefall --- Health & Medicine (General). --- Mykose. --- Zeitschrift. --- Online-Ressource.
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