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This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact

preclinical imaging --- PET --- SPECT --- MRI --- ultrasound --- microscopy --- quantification

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Since the introduction of personalized medicine, the primary focus of imaging has moved from detection and diagnosis to tissue characterization, the determination of prognosis, prediction of treatment efficacy, and measurement of treatment response. Precision (personalized) imaging heavily relies on the use of hybrid technologies and quantitative imaging biomarkers. The growing number of promising theragnostics require accurate quantification for pre- and post-treatment dosimetry. Furthermore, quantification is required in the pharmacokinetic analysis of new tracers and drugs and in the assessment of drug resistance. Positron Emission Tomography (PET) is, by nature, a quantitative imaging tool, relating the time–activity concentration in tissues and the basic functional parameters governing the biological processes being studied. Recent innovations in single photon emission computed tomography (SPECT) reconstruction techniques have allowed for SPECT to move from relative/semi-quantitative measures to absolute quantification. The strength of PET and SPECT is that they permit whole-body molecular imaging in a noninvasive way, evaluating multiple disease sites. Furthermore, serial scanning can be performed, allowing for the measurement of functional changes over time during therapeutic interventions. This Special Issue highlights the hot topics on quantitative PET and SPECT.

Medicine --- Clinical & internal medicine --- PET --- SPECT --- PET/CT --- SPECT/CT --- Absolute quantification --- Quantitative accuracy --- Dynamic PET --- Phantoms --- Repeatability --- Tumor delineation --- Prognosis --- Dosimetry --- Radiomics --- Artificial intelligence --- Deep learning --- Imaging biomarkers --- Tumor segmentation --- Harmonization

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"This book focuses on research developments, models, and practical applications of animal-assisted interventions for diverse populations who have experienced trauma. Physiological and psychological trauma is explored across three broad areas: 1) child maltreatment and family violence; 2) acute and post-traumatic stress, including that which is associated with military service, war, and developmental trauma; and 3) times of crisis, such as natural disasters and the ever-increasing risks associated with climate change, community violence, terrorism, and periods of personal loss and grief. Contributing authors, who include both national and international experts in the fields of human-animal connection and trauma, discuss how our relationships with animals can help build resiliency and foster healing to transform trauma and trauma response."

Resilience, Psychological --- Bonding, Human-Pet --- Trauma and Stressor Related Disorders --- Animal Assisted Therapy --- therapy --- methods --- Animal-Human Bonding --- Human-Pet Bonding --- Pet-Human Bonding --- Animal Human Bonding --- Animal-Human Bondings --- Bonding, Animal-Human --- Bonding, Human Pet --- Bonding, Pet-Human --- Bondings, Animal-Human --- Bondings, Human-Pet --- Bondings, Pet-Human --- Human Pet Bonding --- Pet Human Bonding --- Pet-Human Bondings --- Pets --- Psychological Resilience --- Psychological Resiliences --- Resiliences, Psychological --- Human-Animal Bonding --- Bond, Human-Animal --- Bonding, Human-Animal --- Bonds, Human-Animal --- Human Animal Bond --- Human Animal Bonding --- Human-Animal Bondings --- Human-Animal Bonds --- Human-Pet Bondings --- Resilience, Psychological. --- Human-Animal Bond. --- therapy. --- methods. --- AAT (Animal-assisted therapy) --- Animal-assisted therapy --- Resilience (Personality trait) --- Human-animal relationships. --- Psychic trauma --- Animals --- Post-traumatic stress disorder --- Treatment. --- Therapeutic use. --- Alternative treatment. --- Animal-human relationships --- Animal-man relationships --- Animals and humans --- Human beings and animals --- Man-animal relationships --- Relationships, Human-animal --- Human resilience --- Resiliency (Personality trait) --- Personality --- Psychology --- psychology --- animals --- Resilience

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This book's stated purpose is to provide a discussion of the technical basis and clinical applications of positron emission tomography (PET), as well as their recent progress in nuclear medicine. It also summarizes current literature about research and clinical science in PET. The book is divided into two broad sections: basic science and clinical science. The basic science section examines PET imaging processing, kinetic modeling, free software, and radiopharmaceuticals. The clinical science section demonstrates various clinical applications and diagnoses. The text is intended not only for scientists, but also for all clinicians seeking recent information regarding PET.

Tomography, Emission. --- Computerized emission tomography --- Emission tomography --- PET (Tomography) --- PET-CT (Tomography) --- Positron emission tomography --- Positron emission transaxial tomography --- Radionuclide tomography --- Scintigraphy, Tomographic --- Tomography, Radionuclide --- Diagnosis --- Diagnostic imaging --- Positrons --- Radioisotope scanning --- Data processing --- Emission --- Radiology

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Languages & Literatures --- Germanic Literature --- Jacobsen, J. P. --- Jacobsen, Jens Peter, --- Yaʻakobsen, Yens Peṭer, --- Danemark --- conte de fées --- fantastique (littérature) --- poésie --- littérature danoise --- Copenhague --- Jutland