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Transforming Growth Factor-ß in Cancer Therapy, Volumes 1 and 2, provides a compendium of findings about the role of transforming growth factor-ß (TGF-ß) in cancer treatment and therapy. The second volume, Cancer Treatment and Therapy, is divided into three parts. Part I examines transforming growth factor-ß in developing and advanced cancers. Part II details transforming growth factor-ß in cancer treatment and therapy. Part III includes an investigation into the development of inhibitors of transforming growth factor-ß signaling for therapy. This volume’s companion, Basic and Clinical Biology, examines transforming growth factor-ß signaling in normal physiology, cancer pathobiology, normal and tumor biology, and inflammation and fibrosis. Together, Transforming Growth Factor-ß in Cancer Therapy, Volumes 1 and 2, provide researchers and clinicians with a comprehensive and cutting-edge reference for the findings about the role of transforming growth factor-ß in biology and cancer treatment.

Medicine & Public Health. --- Oncology. --- Cancer Research. --- Cell Biology. --- Pathology. --- Medicine. --- Cytology. --- Médecine --- Cancérologie --- Pathologie --- Cytologie --- Carcinogenesis. --- Transforming growth factors-beta. --- Medicine --- Health & Biological Sciences --- Oncology --- Cancer --- Oncogenesis --- Pathogenesis of cancer --- Tumorigenesis --- Beta transforming growth factors --- TGF-beta (Peptide) --- Transforming growth factor beta --- Pathogenesis --- Cancer research. --- Cell biology. --- Cell biology --- Cellular biology --- Biology --- Cells --- Cytologists --- Disease (Pathology) --- Medical sciences --- Diseases --- Medicine, Preventive --- Tumors --- Cancer research --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Pathology --- Physicians --- Genetic toxicology --- Transforming growth factors --- Oncology  . --- Research.

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En 2008, les progrès des connaissances en matière de la carcinogenèse ont permis d'identifier des cibles moléculaires clés dans la genèse de nombreuses tumeurs solides. Bien que non exhaustives encore, ces informations permettent l'utilisation de composés dirigés contre les cibles moléculaires, spécifiquement activées dans les cancers donnant ainsi naissance au concept de thérapie ciblée. Le trastuzumab, dirigé contre HER2 dont le gène est amplifié dans 20 % des adénocarcinomes du sein, et l'imatinib, inhibiteur de kinase dirigé contre la protéine de fusion bcr/abl, issu de la t(9,22) des leuc

Drug targeting --- Cancer --- Médicaments --- Treatment --- Ciblage --- Traitement --- Epidermal growth factor. --- Treatment. --- Anthelone --- EGF (Growth factor) --- EGF-URO (Growth factor) --- EGF-Urogastrone --- Epidermal growth factor-Urogastrone --- Uroanthelone --- Uroenterone --- Growth factors --- Cancer therapy --- Cancer treatment --- Therapy

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Anemia is a frequent complication of cancer and its treatment. It produces many symptoms and significantly impairs metabolic and physiologic functions as well as patients' activity, well-being and quality of life. Life expectancy is also affected. This book, now being published in its second edition, comprehensively presents the current knowledge on anemia in cancer and its treatment with rhEPO. Future developments are also discussed. Based on updated and new chapters, including a broader spectrum of topics, outstanding international experts describe the scientific and clinical aspects of anemia in various fields of oncology and give diagnostic and therapeutic recommendations on when and how to use rhEPO. The book, considered as a standard work, will again serve as an essential source of information for radiotherapists, medical oncologists, hematologists, internists, pediatricians, surgeons, specialists in transfusion and laboratory medicine, and pharmacologists.

Medicine & Public Health. --- Oncology. --- Radiotherapy. --- Hematology. --- Surgery. --- Pharmacology/Toxicology. --- Blood Transfusion Medicine. --- Medicine. --- Toxicology. --- Blood transfusion. --- Médecine --- Toxicologie --- Radiothérapie --- Hématologie --- Cancérologie --- Chirurgie --- Anemia -- Chemotherapy. --- Antineoplastic agents. --- Cancer -- Chemotherapy -- Complications -- Chemotherapy. --- Drug Design. --- Drug Therapy. --- Recombinant erythropoietin -- Therapeutic use. --- Recombinant erythropoietin --- Anemia --- Cancer --- Colony-Stimulating Factors --- Hematologic Diseases --- Diseases --- Hemic and Lymphatic Diseases --- Hematopoietic Cell Growth Factors --- Glycoproteins --- Erythropoietin --- Neoplasms --- Cytokines --- Proteins --- Intercellular Signaling Peptides and Proteins --- Amino Acids, Peptides, and Proteins --- Chemicals and Drugs --- Peptides --- Biological Factors --- Medicine --- Health & Biological Sciences --- Oncology --- Therapeutic use --- Chemotherapy --- Complications --- Therapeutic use. --- Chemotherapy. --- Cancers --- Carcinoma --- Malignancy (Cancer) --- Malignant tumors --- Anaemia --- Epoetin --- Epogen (Trademark) --- Genetically engineered erythropoietin --- Genetic engineering --- Pharmacology. --- Tumors --- Blood --- Recombinant blood proteins --- Oncology  . --- Blood transfusion --- Blood transfusion therapy --- Hemotherapy --- Transfusion medicine --- Transfusion of blood --- Transfusion therapy --- Transfusion therapy, Blood --- Surgery --- Blood banks --- Blood groups --- Hospitals --- Transfusion-free surgery --- Chemicals --- Pharmacology --- Poisoning --- Poisons --- Surgery, Primitive --- Haematology --- Internal medicine --- Radiation therapy --- Electrotherapeutics --- Medical electronics --- Medical radiology --- Therapeutics, Physiological --- Phototherapy --- Transfusion committees --- Toxicology --- Radiological services --- Drug effects --- Medical pharmacology --- Medical sciences --- Drugs --- Pharmacy --- Physiological effect