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Although regular moderate-intensity exercise can activate important cell adaptive properties, sporadic and strenuous bouts of exercise may induce oxidative stress due to an augmented production of reactive metabolites of oxygen (ROS) and nitrogen free radical species (RNS). Exercise-induced free radical formation may impair cell function by oxidatively modifying nucleic acids, where DNA damage and insufficient repair may lead to genomic instability. Likewise, lipid and protein damage are significant cellular events that can elicit potentially toxic perturbations in cellular homeostasis. This book focuses on aspects of exercise-induced oxidative stress while taking into consideration the basic mechanisms, consequences and function of ROS production, and whether antioxidants may either support or hinder these responses.
ApoE --- exercise --- antioxidants --- oxidative stress --- cognition --- motor --- vitamin E --- vitamin C --- aging --- Alzheimer’s disease --- lymphocytes --- mitochondrial transmembrane potential decline --- thiobarbituric acid reactive substance --- protein carbonyl --- skeletal muscle --- obesity --- fatigue --- diazoxide --- catalase --- superoxide dismutase --- oxidized glutathione --- reduced glutathione --- hemoglobin --- power output --- eccentric exercise --- redox status --- erythrocyte --- metabolism --- probiotics --- physical exercise --- male cyclists --- oxidative stress biomarkers --- antioxidative enzymes --- ultraendurance exercise --- muscle injury --- diet --- reactive oxygen species --- adipose tissue --- antioxidant supplement --- circadian rhythms --- reactive oxygen and nitrogen species (RONS) --- exercise training --- antioxidant --- n/a --- Alzheimer's disease
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Although regular moderate-intensity exercise can activate important cell adaptive properties, sporadic and strenuous bouts of exercise may induce oxidative stress due to an augmented production of reactive metabolites of oxygen (ROS) and nitrogen free radical species (RNS). Exercise-induced free radical formation may impair cell function by oxidatively modifying nucleic acids, where DNA damage and insufficient repair may lead to genomic instability. Likewise, lipid and protein damage are significant cellular events that can elicit potentially toxic perturbations in cellular homeostasis. This book focuses on aspects of exercise-induced oxidative stress while taking into consideration the basic mechanisms, consequences and function of ROS production, and whether antioxidants may either support or hinder these responses.
Research & information: general --- Biology, life sciences --- ApoE --- exercise --- antioxidants --- oxidative stress --- cognition --- motor --- vitamin E --- vitamin C --- aging --- Alzheimer's disease --- lymphocytes --- mitochondrial transmembrane potential decline --- thiobarbituric acid reactive substance --- protein carbonyl --- skeletal muscle --- obesity --- fatigue --- diazoxide --- catalase --- superoxide dismutase --- oxidized glutathione --- reduced glutathione --- hemoglobin --- power output --- eccentric exercise --- redox status --- erythrocyte --- metabolism --- probiotics --- physical exercise --- male cyclists --- oxidative stress biomarkers --- antioxidative enzymes --- ultraendurance exercise --- muscle injury --- diet --- reactive oxygen species --- adipose tissue --- antioxidant supplement --- circadian rhythms --- reactive oxygen and nitrogen species (RONS) --- exercise training --- antioxidant --- ApoE --- exercise --- antioxidants --- oxidative stress --- cognition --- motor --- vitamin E --- vitamin C --- aging --- Alzheimer's disease --- lymphocytes --- mitochondrial transmembrane potential decline --- thiobarbituric acid reactive substance --- protein carbonyl --- skeletal muscle --- obesity --- fatigue --- diazoxide --- catalase --- superoxide dismutase --- oxidized glutathione --- reduced glutathione --- hemoglobin --- power output --- eccentric exercise --- redox status --- erythrocyte --- metabolism --- probiotics --- physical exercise --- male cyclists --- oxidative stress biomarkers --- antioxidative enzymes --- ultraendurance exercise --- muscle injury --- diet --- reactive oxygen species --- adipose tissue --- antioxidant supplement --- circadian rhythms --- reactive oxygen and nitrogen species (RONS) --- exercise training --- antioxidant
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Oxidative stress causes chronic diseases such as cardiovascular disease, cancer, Alzheimer, chronic obstructive pulmonary, and neurodegenerative pathologies. Antioxidant systems defend human cells from free radicals. They act by stopping free radicals, decreasing their development, and quenching the formed ROS and RNS. The antioxidant molecules are classified into primary and secondary defense molecules. The primary antioxidant molecules (i.e., vitamins C and E, ubiquinone, and glutathione) reduce oxidation effects by moving a proton to the free radical species or electron donors, or by terminating the chain reactions The secondary antioxidants (i.e., N-acetyl cysteine and lipoic acid) act as cofactors for some enzyme systems or neutralize the production of free radicals by transition metals. This work comprises original research papers and reviews on antioxidant molecules in food, the agricultural practices that maximize their levels in plants, the potential preventive effects of selected classes of antioxidant molecules, their potential use in functional foods, and the pharmaceutical delivery systems that maximize their potential activity when used as supplements.
Research & information: general --- Biology, life sciences --- Food & society --- Trichoderma spp. --- EVOO --- olive pomace --- olive vegetation water --- Olea europea var Leccino --- HRMS-Orbitrap --- phenolic identification --- antioxidant activity --- grape seed oil fatty acid --- novel extraction --- tocopherol --- supercritical fluid --- microwave assisted --- ultrasound assisted --- Soxhlet --- olive mill wastewater --- olive oil --- Olive Pâté --- antioxidants --- nutraceutical --- Q Exactive Orbitrap LC-MS/MS --- Clery strawberry --- food processing --- Polyphenols --- multi-methodological evaluation --- HS-GC/MS analysis --- PCA --- antioxidant --- HepG2 cells --- EVOO extract --- IOC methods --- LDLR --- PCSK9 --- tomatoes --- NMR spectroscopy --- FT-ICR mass spectrometry --- ripening stage --- phenolics --- metabolomics --- phytochemicals --- cardoon --- multipurpose plant --- chlorogenic acid --- fatty acids --- herbal treatment --- organic zinc --- lamb --- Haemonchus contortus --- antioxidant enzymes --- lipid peroxidation --- mineral status --- paraxanthine --- caffeine --- CYP1A2 phenotyping --- human saliva --- differential pulse voltammetry --- egg --- flavonoids --- inductively coupled plasma mass spectrometry (ICP-MS) --- metallome --- quercetin --- walnut --- by-products --- antitussive --- ROS --- NOx --- IL-6 --- CXC-R1 --- histopathological analysis --- sustainable agriculture --- onion skin --- traditional varieties --- flavonols --- dietary antioxidants, --- Helichrysum --- medicinal plants --- infusions --- phenolic compounds --- antioxidative potential --- polyphenols --- flavonids --- endogenous antioxidant enzymes --- reduced glutathione --- oxidized glutathione --- catalase --- superoxide dismutase --- interleukin 6 --- tumor necrosis factor --- endurance sports --- Ficus carica --- oxidative stress protection --- stress hormones --- epidermal skin barrier --- nutricosmetics --- brown rice --- fermentation --- germination --- stress --- bioactive compounds --- untargeted metabolomics --- functional food --- health benefits --- lovage --- elicitation --- phenolic acids --- potential anti-inflammatory potential --- anticancer properties --- antioxidative activity --- bioactive peptides --- peptidomics --- mass spectrometry --- soybean --- plant-based foods --- LDL --- CVD --- lipid oxidation --- dietary fiber --- cholesterol --- hyperlipidemia --- microalgae --- spirulina --- inflammation --- lipopolysaccharide --- dairy cows --- fattening bulls --- leukocytes --- spices --- condiments --- extra-virgin olive oil --- antiviral properties --- antioxidant properties --- nutricosmetic --- grape seed --- pomace --- polyunsaturated fatty acids --- polyphenol --- resveratrol --- rutin --- HPLC --- GC --- coumarins --- green synthesis --- DFT --- red algae --- antioxidant and antimicrobial ability --- lipoperoxidation --- salmon --- anticancer --- marigold --- sage --- bearberry --- eucalyptus --- yarrow --- apples --- pomegranate --- mitochondrial DNA --- DNA damage --- apoptosis --- oral cancer --- arbutin --- melanin --- pigment --- melasma --- skin lightening --- cosmetic --- hyperpigmentation --- tyrosinase --- nuclear factor erythroid 2-related factor 2 (Nrf2) --- Brassicaceae --- light wavelength --- reactive oxygen species (ROS) --- oxidative stress --- antioxidant proteins --- Moringa leaf extract --- nanoencapsulation --- rabbit --- physiology --- reproduction --- Trichoderma spp. --- EVOO --- olive pomace --- olive vegetation water --- Olea europea var Leccino --- HRMS-Orbitrap --- phenolic identification --- antioxidant activity --- grape seed oil fatty acid --- novel extraction --- tocopherol --- supercritical fluid --- microwave assisted --- ultrasound assisted --- Soxhlet --- olive mill wastewater --- olive oil --- Olive Pâté --- antioxidants --- nutraceutical --- Q Exactive Orbitrap LC-MS/MS --- Clery strawberry --- food processing --- Polyphenols --- multi-methodological evaluation --- HS-GC/MS analysis --- PCA --- antioxidant --- HepG2 cells --- EVOO extract --- IOC methods --- LDLR --- PCSK9 --- tomatoes --- NMR spectroscopy --- FT-ICR mass spectrometry --- ripening stage --- phenolics --- metabolomics --- phytochemicals --- cardoon --- multipurpose plant --- chlorogenic acid --- fatty acids --- herbal treatment --- organic zinc --- lamb --- Haemonchus contortus --- antioxidant enzymes --- lipid peroxidation --- mineral status --- paraxanthine --- caffeine --- CYP1A2 phenotyping --- human saliva --- differential pulse voltammetry --- egg --- flavonoids --- inductively coupled plasma mass spectrometry (ICP-MS) --- metallome --- quercetin --- walnut --- by-products --- antitussive --- ROS --- NOx --- IL-6 --- CXC-R1 --- histopathological analysis --- sustainable agriculture --- onion skin --- traditional varieties --- flavonols --- dietary antioxidants, --- Helichrysum --- medicinal plants --- infusions --- phenolic compounds --- antioxidative potential --- polyphenols --- flavonids --- endogenous antioxidant enzymes --- reduced glutathione --- oxidized glutathione --- catalase --- superoxide dismutase --- interleukin 6 --- tumor necrosis factor --- endurance sports --- Ficus carica --- oxidative stress protection --- stress hormones --- epidermal skin barrier --- nutricosmetics --- brown rice --- fermentation --- germination --- stress --- bioactive compounds --- untargeted metabolomics --- functional food --- health benefits --- lovage --- elicitation --- phenolic acids --- potential anti-inflammatory potential --- anticancer properties --- antioxidative activity --- bioactive peptides --- peptidomics --- mass spectrometry --- soybean --- plant-based foods --- LDL --- CVD --- lipid oxidation --- dietary fiber --- cholesterol --- hyperlipidemia --- microalgae --- spirulina --- inflammation --- lipopolysaccharide --- dairy cows --- fattening bulls --- leukocytes --- spices --- condiments --- extra-virgin olive oil --- antiviral properties --- antioxidant properties --- nutricosmetic --- grape seed --- pomace --- polyunsaturated fatty acids --- polyphenol --- resveratrol --- rutin --- HPLC --- GC --- coumarins --- green synthesis --- DFT --- red algae --- antioxidant and antimicrobial ability --- lipoperoxidation --- salmon --- anticancer --- marigold --- sage --- bearberry --- eucalyptus --- yarrow --- apples --- pomegranate --- mitochondrial DNA --- DNA damage --- apoptosis --- oral cancer --- arbutin --- melanin --- pigment --- melasma --- skin lightening --- cosmetic --- hyperpigmentation --- tyrosinase --- nuclear factor erythroid 2-related factor 2 (Nrf2) --- Brassicaceae --- light wavelength --- reactive oxygen species (ROS) --- oxidative stress --- antioxidant proteins --- Moringa leaf extract --- nanoencapsulation --- rabbit --- physiology --- reproduction
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Oxidative stress causes chronic diseases such as cardiovascular disease, cancer, Alzheimer, chronic obstructive pulmonary, and neurodegenerative pathologies. Antioxidant systems defend human cells from free radicals. They act by stopping free radicals, decreasing their development, and quenching the formed ROS and RNS. The antioxidant molecules are classified into primary and secondary defense molecules. The primary antioxidant molecules (i.e., vitamins C and E, ubiquinone, and glutathione) reduce oxidation effects by moving a proton to the free radical species or electron donors, or by terminating the chain reactions The secondary antioxidants (i.e., N-acetyl cysteine and lipoic acid) act as cofactors for some enzyme systems or neutralize the production of free radicals by transition metals. This work comprises original research papers and reviews on antioxidant molecules in food, the agricultural practices that maximize their levels in plants, the potential preventive effects of selected classes of antioxidant molecules, their potential use in functional foods, and the pharmaceutical delivery systems that maximize their potential activity when used as supplements.
Trichoderma spp. --- EVOO --- olive pomace --- olive vegetation water --- Olea europea var Leccino --- HRMS-Orbitrap --- phenolic identification --- antioxidant activity --- grape seed oil fatty acid --- novel extraction --- tocopherol --- supercritical fluid --- microwave assisted --- ultrasound assisted --- Soxhlet --- olive mill wastewater --- olive oil --- Olive Pâté --- antioxidants --- nutraceutical --- Q Exactive Orbitrap LC-MS/MS --- Clery strawberry --- food processing --- Polyphenols --- multi-methodological evaluation --- HS-GC/MS analysis --- PCA --- antioxidant --- HepG2 cells --- EVOO extract --- IOC methods --- LDLR --- PCSK9 --- tomatoes --- NMR spectroscopy --- FT-ICR mass spectrometry --- ripening stage --- phenolics --- metabolomics --- phytochemicals --- cardoon --- multipurpose plant --- chlorogenic acid --- fatty acids --- herbal treatment --- organic zinc --- lamb --- Haemonchus contortus --- antioxidant enzymes --- lipid peroxidation --- mineral status --- paraxanthine --- caffeine --- CYP1A2 phenotyping --- human saliva --- differential pulse voltammetry --- egg --- flavonoids --- inductively coupled plasma mass spectrometry (ICP-MS) --- metallome --- quercetin --- walnut --- by-products --- antitussive --- ROS --- NOx --- IL-6 --- CXC-R1 --- histopathological analysis --- sustainable agriculture --- onion skin --- traditional varieties --- flavonols --- dietary antioxidants, --- Helichrysum --- medicinal plants --- infusions --- phenolic compounds --- antioxidative potential --- polyphenols --- flavonids --- endogenous antioxidant enzymes --- reduced glutathione --- oxidized glutathione --- catalase --- superoxide dismutase --- interleukin 6 --- tumor necrosis factor --- endurance sports --- Ficus carica --- oxidative stress protection --- stress hormones --- epidermal skin barrier --- nutricosmetics --- brown rice --- fermentation --- germination --- stress --- bioactive compounds --- untargeted metabolomics --- functional food --- health benefits --- lovage --- elicitation --- phenolic acids --- potential anti-inflammatory potential --- anticancer properties --- antioxidative activity --- bioactive peptides --- peptidomics --- mass spectrometry --- soybean --- plant-based foods --- LDL --- CVD --- lipid oxidation --- dietary fiber --- cholesterol --- hyperlipidemia --- microalgae --- spirulina --- inflammation --- lipopolysaccharide --- dairy cows --- fattening bulls --- leukocytes --- spices --- condiments --- extra-virgin olive oil --- antiviral properties --- antioxidant properties --- nutricosmetic --- grape seed --- pomace --- polyunsaturated fatty acids --- polyphenol --- resveratrol --- rutin --- HPLC --- GC --- coumarins --- green synthesis --- DFT --- red algae --- antioxidant and antimicrobial ability --- lipoperoxidation --- salmon --- anticancer --- marigold --- sage --- bearberry --- eucalyptus --- yarrow --- apples --- pomegranate --- mitochondrial DNA --- DNA damage --- apoptosis --- oral cancer --- arbutin --- melanin --- pigment --- melasma --- skin lightening --- cosmetic --- hyperpigmentation --- tyrosinase --- nuclear factor erythroid 2-related factor 2 (Nrf2) --- Brassicaceae --- light wavelength --- reactive oxygen species (ROS) --- oxidative stress --- antioxidant proteins --- Moringa leaf extract --- nanoencapsulation --- rabbit --- physiology --- reproduction --- n/a --- Olive Pâté
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