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Myocarditis, the inflammation of the heart muscle, could be in some cases serious and potentially fatal disease. This book is a comprehensive compilation of studies from leading international experts on various aspects of myocarditis. The first section of the book provides a clinical perspective on the disease. It contains comprehensive reviews of the causes of myocarditis, its classification, diagnosis, and treatment. It also includes reviews of Perimyocarditis; Chagas' chronic myocarditis, and myocarditis in HIV-positive patients. The second section of the book focuses on the pathogenesis of myocarditis, discussing pathways and mechanisms activated during viral infection and host immune response during myocarditis. The third, and final, section discusses new findings in the pathogenesis that may lead to new directions for clinical diagnosis, including use of new biomarkers, and new treatments of myocarditis.
Myocarditis. --- Myocardium --- Myositis --- Inflammation --- Diseases --- Cardiovascular medicine
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This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact
immunity --- inflammation --- cardiovascular disease --- arrhythmias --- heart failure --- myocarditis --- valve disease
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This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact
Medicine --- immunity --- inflammation --- cardiovascular disease --- arrhythmias --- heart failure --- myocarditis --- valve disease --- immunity --- inflammation --- cardiovascular disease --- arrhythmias --- heart failure --- myocarditis --- valve disease
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This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact
Medicine --- immunity --- inflammation --- cardiovascular disease --- arrhythmias --- heart failure --- myocarditis --- valve disease
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Myocarditis is a clinical syndrome, most frequently of infectious etiology, that occurs with a broad range of relatively non-specific symptoms, and consists of an inflammatory process of the heart with necrosis and degeneration of the myocardium by inflammatory infiltration of immune cells. The infection can cause direct injury of cardiomyocytes as well as immune-mediated destruction of the myocardium, leading to cardiac dysfunction. In this book, the broad aspects of myocarditis are fully presented by leading international experts. The texts are devoted to both clinical aspects and pathophysiology, and they present comprehensive reviews of the causes of myocarditis, its classification, diagnosis, and treatment, as well as myocarditis in special populations such as pediatric, peripartum and chronic chagasic myocarditis.
Myocarditis. --- Cardiovascular pharmacology. --- Cardiovascular system --- Pharmacology --- Myocardium --- Myositis --- Drug effects --- Effect of drugs on --- Inflammation --- Diseases --- Cardiovascular medicine
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This book is an up-to-date, comprehensive, clinically oriented guide to the diagnosis and treatment of patients with myocarditis. The opening chapters address the classification, histopathology and molecular diagnosis, as well as the polymorphic clinical presentations, ranging from myocardial infarction with normal coronary arteries; arrhythmias of variable type and clinical severity and fulminant, acute, sub-acute or chronic heart failure; to life-threatening unexplained cardiogenic shock and sudden cardiac death. Including chapters from leading International experts in the field, it covers all key issues from bench to bedside. Topics presented include epidemiology, etiology, pathogenesis, clinical and diagnostic work-up, the role of endomyocardial biopsy and of non-invasive cardiac imaging, risk stratification, and cardiological and etiology-specific management and follow-up. For each topic, a comprehensive review of the current literature is provided and practical suggestions are offered for short- and long-term management. Lastly, future perspectives and gaps in the current knowledge are also addressed. The book also covers a key discovery of last the 2 decades, namely the autoimmune origin of myocarditis in a sizable proportion of patients, discussing in detail the role of immunosuppression and immunomodulation, as well as the need for a multidisciplinary approach to the disease. Mainly intended for cardiologists, general physicians, clinical immunologists and rheumatologists, it is also a valuable tool for residents in Cardiology, Internal Medicine, Clinical Immunology and Rheumatology.
Cardiology. --- Rheumatology. --- Immunology. --- Immunobiology --- Life sciences --- Serology --- Internal medicine --- Connective tissues --- Joints --- Heart --- Diseases --- Myocarditis. --- Myocardium --- Myositis --- Inflammation
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Immune response --- Myocarditis. --- Regulation. --- Myocardium --- Myositis --- Immune modulation --- Immunity --- Immunomodulation --- Immunoregulation --- Regulation of immunity --- Regulation of the immune response --- Idiotypic networks --- Biological response modifiers --- Ir genes --- Inflammation --- Diseases --- Regulation --- Miocarditis --- Resposta immunitària
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Cardiomyopathy is one of the most frequent causes of heart failure, and a leading entity of cardiac transplantation in the era of modern heart failure regimens. This volume focuses on major advances in inflammatory cardiomyopathy (DCMi) during the past 10 years. The book is divided up into the following sections: 1. Myocarditis and inflammatory cardiomyopathy – clinical management, epidemiology and prognosis; 2. Animal Models of myocarditis – autoimmunity and viral infection and therapeutic interventions; 3. Alterations of the immune system in human viral and inflammatory cardiomyopathy; 4. Diagnostic concepts of inflammatory and viral cardiomyopathy in endomyocardial biopsies (EMBs) including cardiac magnetic resonance; 5. Conventional and immunomodulatory treatment strategies in inflammatory cardiomyopathy patients. An international group of authors discusses topics as the histological Dallas criteria for clinical diagnostics, emerging relevance of immunohistological detection of DCMi and detectability of viruses in EMBs, and epidemiology and standard clinical treatment of acute myocarditis and dilated cardiomyopathy patients. This volume serves as a valuable source for cardiologists and cardiovascular pathologists to update their knowledge on DCMi, a still enigmatic and fascinating cardiovascular disorder, which has made major steps from bench to bedside in the past decade.
Inflammation. --- Myocarditis. --- Myocardium -- Diseases. --- Myocarditis --- Cardiomegaly --- Cardiomyopathies --- Heart Diseases --- Cardiovascular Diseases --- Diseases --- Cardiomyopathy, Dilated --- Medicine --- Biology --- Health & Biological Sciences --- Microbiology & Immunology --- Myocardium --- Diseases. --- Cardiomyopathy --- Myocardial diseases --- Myocardiopathies --- Myocardiopathy --- Inflammation --- Medicine. --- Immunology. --- Pharmacology. --- Virology. --- Internal medicine. --- Cardiology. --- Infectious diseases. --- Biomedicine. --- Infectious Diseases. --- Pharmacology/Toxicology. --- Internal Medicine. --- Myositis --- Medical virology. --- Emerging infectious diseases. --- Toxicology. --- Medicine, Internal --- Chemicals --- Pharmacology --- Poisoning --- Poisons --- Emerging infections --- New infectious diseases --- Re-emerging infectious diseases --- Reemerging infectious diseases --- Communicable diseases --- Medical microbiology --- Virology --- Virus diseases --- Heart --- Internal medicine --- Immunobiology --- Life sciences --- Serology --- Toxicology --- Microbiology --- Drug effects --- Medical pharmacology --- Medical sciences --- Chemotherapy --- Drugs --- Pharmacy --- Physiological effect
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Cardiomyopathies --- Myocarditis --- Virus Diseases --- Viral Diseases --- Viral Infections --- Virus Infections --- Disease, Viral --- Disease, Virus --- Diseases, Viral --- Diseases, Virus --- Infection, Viral --- Infection, Virus --- Infections, Viral --- Infections, Virus --- Viral Disease --- Viral Infection --- Virus Disease --- Virus Infection --- Carditis --- Myocarditides --- Cardiomyopathies, Primary --- Cardiomyopathies, Secondary --- Primary Myocardial Diseases --- Secondary Myocardial Diseases --- Myocardial Diseases --- Myocardial Diseases, Primary --- Myocardial Diseases, Secondary --- Myocardiopathies --- Cardiomyopathy --- Cardiomyopathy, Primary --- Cardiomyopathy, Secondary --- Disease, Myocardial --- Disease, Primary Myocardial --- Disease, Secondary Myocardial --- Diseases, Myocardial --- Diseases, Primary Myocardial --- Diseases, Secondary Myocardial --- Myocardial Disease --- Myocardial Disease, Primary --- Myocardial Disease, Secondary --- Myocardiopathy --- Primary Cardiomyopathies --- Primary Cardiomyopathy --- Primary Myocardial Disease --- Secondary Cardiomyopathies --- Secondary Cardiomyopathy --- Secondary Myocardial Disease --- Virus diseases. --- Heart --- Myocardial diseases. --- Myocarditis. --- Diseases. --- Infections. --- Virus diseases --- Viral diseases --- Viral infections --- Virus infections --- Communicable diseases --- Medical virology --- Pathogenic viruses --- Cardiac infections --- Heart infections --- Cardiac diseases --- Heart diseases --- Cardiology --- Diseases --- Infections --- Infectious diseases
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