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Genetic transcription --- Transcription, Genetic --- Genetic transcription. --- Transcription (Genetics) --- Genetic code --- Transcription, Genetic. --- Early Gene Transcription --- Genetic Transcription --- Late Gene Transcription --- Gene Transcription, Early --- Gene Transcription, Late --- Transcription, Early Gene --- Transcription, Late Gene --- DNA, Ribosomal --- Antisense Elements (Genetics) --- Genetics
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transcription. --- gene transcription --- Transcription factors --- Bioinformatics --- gene interaction --- messenger RNA --- degradation. --- Interactomique --- Interactomique
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The book introduces readers to the latest developments in biotechnological methods used for improving the cultivation of silkworms. The text focuses on implementing biotechnological approaches, ranging from basic to advanced techniques, on enhancing silk production, increasing abiotic stress resilience, improving disease tolerance, and developing resistance in silkworm crops. With the current climate crisis and growing demand for high-quality silk, biotechnological applications have become essential in addressing the urgent need to increase silk production. The field of sericulture has made significant breakthroughs, such as identifying DNA markers, linkage association, genome-wide association studies, generating mutants, and introducing transgenic silkworms. Developing silkworms with improved cocoon yield and disease resistance is crucial to boost silk production. The book covers fundamental principles and recent advancements and delves into various methodologies employed inseri-biotechnology for improving silkworm crops. These methodologies include next-generation sequencing for DNA sequencing, using molecular markers to enhance abiotic stress tolerance (specifically high temperature and humidity conditions), expression analysis, RNA interference, gene knockout approaches to bolster disease resistance, and transcriptomics to enhance economically significant parameters such as silk content. The book explains these topics in detail and includes contemporary research appraisals, extensive discussions, and an evaluation of the benefits and risks associated with the use of biotechnological tools. This book serves as an invaluable reference for researchers and academics in biotechnology, molecular biology, and sericulture while also serving as an informative starting point for budding researchers.
Biotechnology. --- Genetic transcription. --- Biology --- Genomics. --- Biology. --- Gene Transcription. --- Biological Techniques. --- Genomic Analysis. --- Biological Sciences. --- Technique.
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This volume presents the most recent advances in techniques for studying the post-transcriptional regulation of gene expression (PTR). With sections on bioinformatics approaches, expression profiling, the protein and RNA interactome, the mRNA lifecycle, and RNA modifications, the book guides molecular biologists toward harnessing the power of this new generation of techniques, while also introducing the data analysis skills that these high-throughput techniques require. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and up-to-date, Post-Transcriptional Gene Regulation, Third Edition serves as a versatile resource for researchers studying post-transcriptional regulation by both introducing the most recent techniques and providing a comprehensive guide to their implementation. Chapter 6 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
Biology—Technique. --- Gene expression. --- Genetic transcription. --- Gene Expression Analysis. --- Gene Transcription. --- Transcription (Genetics) --- Genetic code --- Genes --- Genetic regulation --- Expression
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This book covers various state-of-the-art techniques regarding the associations between transcription factors (TFs) and genes, with a focus on providing methodological and practical references for researchers. The contents cover diverse protocols and summaries of TFs including screening of TF-DNA interactions, detection of open chromatin regions, identification of epigenetic regulations, engineering TFs with genome editing tools, detection of transcriptional activities, computational analysis of TF networks, functions and druggabilities of TFs in biomedical research, and much more. Written for the highly successful Methods in Molecular Biology series, chapters feature the kind of detailed implementation advice from the experts to ensure successful research results. Authoritative and cutting-edge, Transcription Factor Regulatory Networks aims to benefit readers who are interested in using state-of-the-art techniques to study TFs and their myriad effects in cellular life.
Genetic transcription. --- Biology—Technique. --- Gene expression. --- Gene Transcription. --- Gene Expression Analysis. --- Transcription (Genetics) --- Genetic code --- Genes --- Genetic regulation --- Expression
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This book provides a comprehensive overview of genomics and its diverse applications. Chapters cover genomics data generation methods, computational tools, gene annotation, transcriptomics, DNA barcoding, next-generation sequencing, functional genomics, metagenomics, synthetic genomics, microarray analysis, nutrigenomics, genome editing, and more. This book offers a valuable source of information for not only beginners in genomics, but also for students, researchers, scientists, clinicians, practitioners, policymakers, and stakeholders who are interested in harnessing the potential of genomics in many areas.
Genetics. --- Genomics. --- Genetic transcription. --- Pharmacovigilance. --- Synthetic Biology. --- Biology --- Genetics and Genomics. --- Gene Transcription. --- Drug Safety and Pharmacovigilance. --- Biological Techniques. --- Technique.
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This book delves into the fascinating realm of eukaryotic gene regulation. The specific expression of genes shapes the phenotype of cells and tissues. The regulation of gene expression, including up- and downregulation, is a fundamental aspect of nearly all physiological processes, both in health and disease. These dynamic processes respond to various daily challenges, such as dietary changes and infections. Therefore, it is crucial for not only biologists and biochemists but also all students in biomedical disciplines to understand gene regulation concepts. This foundational knowledge will benefit them in their specialized fields. A comprehensive understanding of transcription factors and the mechanisms that alter their activity is a fundamental goal of modern life science research. Epigenetics refers to the packaging and accessibility of the genome in each of the trillions of cells in our bodies. The prefix “epi” (meaning “upon,” “above,” or “beyond”) indicates that epigenetic processes do not alter the DNA sequence of our genome, adding a layer of information beyond that encoded in our genome. Genomic DNA is wrapped around complexes of histone proteins, helping it fit into a cell nucleus with a diameter of less than 10 μm. This protein-DNA complex is known as chromatin. The content of this book is linked to the “Molecular Medicine and Genetics” course, which the author has lectured on in various forms since 2002 at the University of Eastern Finland in Kuopio. This book is an updated version of the textbooks “Mechanisms of Gene Regulation” and “Human Epigenomics.” It is divided into 16 chapters. Following two introductory chapters, four chapters explore gene regulation from the perspective of transcription factors, while another four chapters focus on chromatin and non-coding RNA. Three chapters then discuss the impact of epigenetics from a health perspective, and the final three chapters address epigenetics from the perspective of diseases. A glossary in the appendix explains the major specialist terms.
Molecular biology. --- Genetic transcription. --- Epigenetics. --- Genomics. --- Molecular genetics. --- Medicine --- Biology --- Molecular Biology. --- Gene Transcription. --- Molecular Genetics. --- Biomedical Research. --- Research.
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This book describes transcription factors in the context of hematopoietic development and reveal mechanistic insights how they orchestrate specific gene expression patterns. Several examples from lymphoid and myeloid lineages are given as well as particular examples of leukemia fusion proteins that contain a part of a transcription factor. In the given chapters covering each one particular example, the function of transcription factors is characterized in normal as well as leukemic contexts. New technologies such as ChIP-Seq or RNA-Seq, that make use of genome-wide sequencing, have shown that such master regulators of blood cell development often work in combinatorial fashion and, when dysregulated, results in leukemogenesis. This book is not only intended for experts but it should also be a useful resource for younger scientists or scientists from other disciplines, who may use this book as a stimulating starting point for further discoveries and/ or translational endeavors.
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Eukaryotic Cells. --- Gene Expression Regulation. --- Transcription, Genetic. --- 577.21 --- #WPLT:dd.prof.J.Vendrig --- Early Gene Transcription --- Genetic Transcription --- Late Gene Transcription --- Gene Transcription, Early --- Gene Transcription, Late --- Transcription, Early Gene --- Transcription, Late Gene --- DNA, Ribosomal --- Antisense Elements (Genetics) --- Expression Regulation, Gene --- Regulation, Gene Action --- Regulation, Gene Expression --- Gene Action Regulation --- Regulation of Gene Expression --- RNAi Therapeutics --- Gene Regulatory Networks --- Cell, Eukaryotic --- Cells, Eukaryotic --- Eukaryotic Cell --- Molecular mechanism of coding, storage and realization of inheritance information. Molecular genetics. Molecular biology of the gene --- Eukaryotic cells. --- Genetic regulation. --- Genetic transcription. --- Cells. --- 577.21 Molecular mechanism of coding, storage and realization of inheritance information. Molecular genetics. Molecular biology of the gene --- Eukaryotic cells --- Genetic regulation --- Genetic transcription --- Eukaryotic Cells --- Gene Expression Regulation --- Transcription, Genetic --- Transcription (Genetics) --- Genetic code --- Gene expression --- Gene expression regulation --- Gene regulation --- Biosynthesis --- Cellular control mechanisms --- Molecular genetics --- Eucaryotic cells --- Cells --- Protista --- Regulation --- Transcription, genetic
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Cells. --- Cell Biology. --- Genetic Engineering. --- Transcription, Genetic. --- Early Gene Transcription --- Genetic Transcription --- Late Gene Transcription --- Gene Transcription, Early --- Gene Transcription, Late --- Transcription, Early Gene --- Transcription, Late Gene --- DNA, Ribosomal --- Antisense Elements (Genetics) --- Engineering, Genetic --- Intervention, Genetic --- Genetic Intervention --- Genetic Interventions --- Interventions, Genetic --- Biotechnology --- Cloning, Molecular --- DNA, Recombinant --- Industrial Microbiology --- Artificial Gene Fusion --- Organisms, Genetically Modified --- Animals, Genetically Modified --- Plants, Genetically Modified --- Cellular Biology --- Cytology --- Biologies, Cell --- Biologies, Cellular --- Biology, Cell --- Biology, Cellular --- Cell Biologies --- Cellular Biologies --- Cell --- Cell Biology --- Basic Sciences. Biology --- Eukaryotic cells --- Genetic engineering --- Recombinant DNA --- Transcription, Genetic --- CELLS. --- CYTOLOGY --- GENETIC INTERVENTION, congresses. --- TRANSCRIPTION --- congresses. --- GENETIC. --- Cellular Biology. --- Basic sciences. biology --- Genetic intervention, congresses. --- Genetic intervention --- Recombinant dna --- Transcription --- Transcription, genetic --- Cellular biology. --- Congresses. --- Genetic. --- Cells --- Genetic Engineering
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