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This book contains the art and science in current standards of surgical treatment of pancreatic ductal adenocarcinoma. It explains the clinical role of surgical resection during multimodal treatment in patients with pancreatic ductal adenocarcinoma, novel surgical techniques including extended pancreatectomy and minimally invasive surgery, risk of cancer in IPMN, and the clinical importance of liquid biopsy.

unresectable pancreatic ductal adenocarcinoma --- conversion surgery --- early recurrence --- pancreatic neoplasm/analysis --- pancreatic neoplasm/surgery --- tumor location --- survival --- clinical staging --- branch duct intraductal papillary mucinous neoplasm --- risk factor --- malignancy --- meta-analysis --- laparoscopic --- pancreaticoduodenectomy --- pancreatic cancer --- borderline resectable --- neoadjuvant treatment --- chemoradiotherapy --- prognostic nutritional index --- isolated local recurrence --- pancreatectomy --- pancreatic remnant --- recurrence --- redo surgery --- pancreatic exocrine insufficiency --- adjuvant chemotherapy --- biliary drainage --- prehabilitation --- ERAS --- arterial resection --- total pancreatectomy --- neoadjuvant therapy --- pancreatic ductal adenocarcinoma --- surgical treatment --- technical advances --- pancreatic main duct dilatation --- intraductal papillary mucinous neoplasm --- high grade dysplasia --- invasive carcinoma --- pancreatic cystic neoplasm --- cell-free DNA --- mesopancreas --- superior mesenteric artery --- nerve and fibrous tissues --- lymph node dissection --- R0 resection --- n/a

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The rapid aging of populations in developed countries since the 2000s has placed increasing attention on the issue of musculoskeletal disorders in elderly patients. Notably, spinal disorders not only restrict the social activities of elderly patients, but they also lead to economic loss for society. “Current Advances in Spinal Diseases of Elderly Patients” is a topical collection of articles about current perspectives on diagnosis and treatment of spinal disorders including current surgical strategies. This Special Issue covers a broad range of issues, ranging from managing refractory states such as severe osteoporosis, spinal deformity, ossification of the spinal ligaments, and multiple arthropathy to managing lifestyle-related spinal diseases during the COVID-19 pandemic in elderly populations. We hope that the readers of this Special Issue find the contents interesting.

Medicine --- Pharmacology --- spinal metastasis --- non-small cell lung cancer --- decompression --- survival --- prognosis --- epidermal growth factor receptor --- Uno's C-index --- New England Spinal Metastasis Score --- trunk muscle --- bioelectrical impedance analysis --- MRI --- back muscle strength --- epidemiological study --- osteoporosis --- osteopenia --- locomotive syndrome --- two-step test --- frailty --- cervical myelopathy --- hand grip strength --- falls --- postoperative --- human nonmercaptalbumin --- reduced albumin --- oxidative stress --- spinal sagittal alignment --- low back pain --- health-related quality of life --- conus medullaris --- height --- pelvic incidence --- magnetic resonance imaging --- healthy volunteers --- gender differences --- spine arthrodesis --- spinal fusion --- spine --- deformity --- direct lateral corpectomy --- expandable cage --- global alignment --- local kyphosis --- osteoporosis vertebral fracture --- cervical spine --- clinical findings --- computed tomography --- diffuse idiopathic skeletal hyperostosis --- ossification of the posterior longitudinal ligament --- pain --- patient-reported outcomes --- whole spine --- prevalence --- influence factor --- spinal alignment --- aging --- total knee arthroplasty --- lumbar lordosis --- sagittal spinopelvic parameters --- clinical outcome --- cervical ossification of the posterior longitudinal ligament --- whole-spine computed tomography --- grading system --- multicenter study --- adult spinal deformity (ASD) --- posterior lumbar interbody fusion --- lateral lumbar interbody fusion --- sagittal correction --- perioperative complications --- surgical invasiveness --- degenerative adult deformity --- anterior cervical corpectomy and fusion --- hybrid fusion --- implant failure --- graft subsidence --- complications --- perioperative outcomes --- fusion rate --- segmental paralysis --- mechanical stability --- resident cohort --- resident registry --- spinal balance --- gender --- adult spine --- osteoporotic vertebral fracture --- residual pain --- visual analog scale --- quality of life --- adult spine deformity --- adult spine fusion --- deformity correction --- perioperative parameters --- ODI --- VAS --- disability --- T1 slope --- C2-7 SVA --- C2-7 angle --- back pain --- brace --- spine orthoses --- lumbar support --- spine support --- COVID-19 --- pandemic --- spinal disorder --- elderly --- exercise habit --- female --- activities of daily living --- nutrition --- health checkup data --- full-endoscopic lumbar discectomy --- recurrent herniation --- early recurrence --- spinal metastasis --- non-small cell lung cancer --- decompression --- survival --- prognosis --- epidermal growth factor receptor --- Uno's C-index --- New England Spinal Metastasis Score --- trunk muscle --- bioelectrical impedance analysis --- MRI --- back muscle strength --- epidemiological study --- osteoporosis --- osteopenia --- locomotive syndrome --- two-step test --- frailty --- cervical myelopathy --- hand grip strength --- falls --- postoperative --- human nonmercaptalbumin --- reduced albumin --- oxidative stress --- spinal sagittal alignment --- low back pain --- health-related quality of life --- conus medullaris --- height --- pelvic incidence --- magnetic resonance imaging --- healthy volunteers --- gender differences --- spine arthrodesis --- spinal fusion --- spine --- deformity --- direct lateral corpectomy --- expandable cage --- global alignment --- local kyphosis --- osteoporosis vertebral fracture --- cervical spine --- clinical findings --- computed tomography --- diffuse idiopathic skeletal hyperostosis --- ossification of the posterior longitudinal ligament --- pain --- patient-reported outcomes --- whole spine --- prevalence --- influence factor --- spinal alignment --- aging --- total knee arthroplasty --- lumbar lordosis --- sagittal spinopelvic parameters --- clinical outcome --- cervical ossification of the posterior longitudinal ligament --- whole-spine computed tomography --- grading system --- multicenter study --- adult spinal deformity (ASD) --- posterior lumbar interbody fusion --- lateral lumbar interbody fusion --- sagittal correction --- perioperative complications --- surgical invasiveness --- degenerative adult deformity --- anterior cervical corpectomy and fusion --- hybrid fusion --- implant failure --- graft subsidence --- complications --- perioperative outcomes --- fusion rate --- segmental paralysis --- mechanical stability --- resident cohort --- resident registry --- spinal balance --- gender --- adult spine --- osteoporotic vertebral fracture --- residual pain --- visual analog scale --- quality of life --- adult spine deformity --- adult spine fusion --- deformity correction --- perioperative parameters --- ODI --- VAS --- disability --- T1 slope --- C2-7 SVA --- C2-7 angle --- back pain --- brace --- spine orthoses --- lumbar support --- spine support --- COVID-19 --- pandemic --- spinal disorder --- elderly --- exercise habit --- female --- activities of daily living --- nutrition --- health checkup data --- full-endoscopic lumbar discectomy --- recurrent herniation --- early recurrence

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

The rapid aging of populations in developed countries since the 2000s has placed increasing attention on the issue of musculoskeletal disorders in elderly patients. Notably, spinal disorders not only restrict the social activities of elderly patients, but they also lead to economic loss for society. “Current Advances in Spinal Diseases of Elderly Patients” is a topical collection of articles about current perspectives on diagnosis and treatment of spinal disorders including current surgical strategies. This Special Issue covers a broad range of issues, ranging from managing refractory states such as severe osteoporosis, spinal deformity, ossification of the spinal ligaments, and multiple arthropathy to managing lifestyle-related spinal diseases during the COVID-19 pandemic in elderly populations. We hope that the readers of this Special Issue find the contents interesting.

spinal metastasis --- non-small cell lung cancer --- decompression --- survival --- prognosis --- epidermal growth factor receptor --- Uno’s C-index --- New England Spinal Metastasis Score --- trunk muscle --- bioelectrical impedance analysis --- MRI --- back muscle strength --- epidemiological study --- osteoporosis --- osteopenia --- locomotive syndrome --- two-step test --- frailty --- cervical myelopathy --- hand grip strength --- falls --- postoperative --- human nonmercaptalbumin --- reduced albumin --- oxidative stress --- spinal sagittal alignment --- low back pain --- health-related quality of life --- conus medullaris --- height --- pelvic incidence --- magnetic resonance imaging --- healthy volunteers --- n/a --- gender differences --- spine arthrodesis --- spinal fusion --- spine --- deformity --- direct lateral corpectomy --- expandable cage --- global alignment --- local kyphosis --- osteoporosis vertebral fracture --- cervical spine --- clinical findings --- computed tomography --- diffuse idiopathic skeletal hyperostosis --- ossification of the posterior longitudinal ligament --- pain --- patient-reported outcomes --- whole spine --- prevalence --- influence factor --- spinal alignment --- aging --- total knee arthroplasty --- lumbar lordosis --- sagittal spinopelvic parameters --- clinical outcome --- cervical ossification of the posterior longitudinal ligament --- whole-spine computed tomography --- grading system --- multicenter study --- adult spinal deformity (ASD) --- posterior lumbar interbody fusion --- lateral lumbar interbody fusion --- sagittal correction --- perioperative complications --- surgical invasiveness --- degenerative adult deformity --- anterior cervical corpectomy and fusion --- hybrid fusion --- implant failure --- graft subsidence --- complications --- perioperative outcomes --- fusion rate --- segmental paralysis --- mechanical stability --- resident cohort --- resident registry --- spinal balance --- gender --- adult spine --- osteoporotic vertebral fracture --- residual pain --- visual analog scale --- quality of life --- adult spine deformity --- adult spine fusion --- deformity correction --- perioperative parameters --- ODI --- VAS --- disability --- T1 slope --- C2-7 SVA --- C2-7 angle --- back pain --- brace --- spine orthoses --- lumbar support --- spine support --- COVID-19 --- pandemic --- spinal disorder --- elderly --- exercise habit --- female --- activities of daily living --- nutrition --- health checkup data --- full-endoscopic lumbar discectomy --- recurrent herniation --- early recurrence --- Uno's C-index