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This book is a printed edition of the Special Issue Promising Detoxification Strategies to Mitigate Mycotoxins in Food and Feed that was published in Toxins

Trichoderma --- n/a --- photodegradation product --- physical decontamination --- growth performance --- toxigenic Fusarium --- curcumin --- mitigation --- Aspergillus flavus --- food and beverage --- ascladiol --- biological control --- antioxidant capability --- trichothecene --- bioprospecting --- turkey --- processing --- chicks --- Sporobolomyces sp. IAM 13481 --- mycotoxins --- epimer --- Tri101 --- enzymes --- neutral electrolyzed water --- antioxidant function --- purification --- ameliorating effects --- aflatoxin-degrading enzyme --- chemical decontamination --- desoxypatulinic acid --- furan rings --- maize --- atmospheric pressure --- biotransformation --- estrogen receptor (ER) --- oxidative stress --- decontamination --- Bacillus shackletonii --- hyssop --- DBD --- degradation --- TQEF-MS/MS --- CYP450 --- enzymatic detoxification --- low temperature plasma --- Fusarium --- AFBO–DNA --- modified mycotoxin --- Bacillus subtilis ANSB060 --- polarity --- thermal treatment --- serum hormones --- mycotoxins mitigation --- mycotoxin --- zearalenone (ZEA) --- cell viability --- detoxification --- patulin --- biodegradation --- interactions --- intracellular and extracellular enzymes --- Bacillus licheniformis CK1 --- deoxynivalenol --- aflatoxins --- aflatoxin B1 --- biological decontamination --- Corylus avellana --- molecular --- Pichia caribbica --- mild technologies --- microbial patulin degradation --- enzyme --- proteomics --- fatty acids --- spores of Ganoderma lucidum --- inhibition --- residue --- food safety --- cold atmospheric pressure plasma technology --- application --- post-weaning female piglets --- laccase --- aflatoxin biodegradation preparation --- Aflatoxin B1 --- microorganism identification --- AFBO-DNA

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Crop contamination by mycotoxins is a global problem that poses significant economic burdens due to a number of factors, including the food/feed losses that are caused by reduced production rates; the resulting adverse effects on human and animal health and productivity; and the trade losses associated with the costs incurred by inspection, sampling, and analysis before and after shipments. In this scenario, the development of fit-for-purpose analytical methods for regulated and (re)-emerging mycotoxins continues to be a dynamic research area. Some of the current trends in this research area are presented in this book. The collected contributions address either the need for improved methods for mycotoxin detection addressed by new or incoming regulation (ergot alkaloids and Alternaria toxins) as well as methods for the detection of multiple mycotoxins. New approaches to enhance the performance of well-established methodologies, such as the enzyme-linked immunosorbent assay (ELISA) and fluorescence polarization immunoassays (FPIA), are also addressed.

Research & information: general --- Chemistry --- Analytical chemistry --- FPIA --- mycotoxin --- OTA --- detection methods --- food safety --- monoclonal antibody (mAb) --- tracer --- HPLC --- trichothecenes --- zearalenone --- Fusarium toxins --- wheat --- liquid chromatography-mass spectrometry --- official control --- collaborative study --- ergot alkaloids --- sum parameter method --- hydrazinolysis --- esterification --- swine feed --- dairy feed --- UHPLC-MS/MS --- aflatoxin B1 --- recombinant AflR gene --- VICAM --- I-ELISA --- peanut --- wheat flour --- milk powder --- LC-MS/MS method --- cereal products --- occurrence --- alternariol --- antibody --- ELISA --- hapten design --- immunoassay --- linker site --- FPIA --- mycotoxin --- OTA --- detection methods --- food safety --- monoclonal antibody (mAb) --- tracer --- HPLC --- trichothecenes --- zearalenone --- Fusarium toxins --- wheat --- liquid chromatography-mass spectrometry --- official control --- collaborative study --- ergot alkaloids --- sum parameter method --- hydrazinolysis --- esterification --- swine feed --- dairy feed --- UHPLC-MS/MS --- aflatoxin B1 --- recombinant AflR gene --- VICAM --- I-ELISA --- peanut --- wheat flour --- milk powder --- LC-MS/MS method --- cereal products --- occurrence --- alternariol --- antibody --- ELISA --- hapten design --- immunoassay --- linker site

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Microbial contamination of agriculture and food commodities may cause significant losses, with economic, social and environmental consequences. Therefore, the search for new, promising substances that demonstrate antagonism towards different microorganisms has been observed in recent years. Different plants, as well as differentiated methods of obtaining of biological compounds, are the research subject. Moreover, current trends focus on the sustainable recovery of antimicrobial substances from waste materials. The contributed articles present original research with a focus on: The biological activity of plant-derived extracts and oils: the research is concentrated on the discovery of new sufficient antimicrobial substances, characterized by broad biological properties including antibacterial, antifungal, antimycotoxigenic and cytotoxic activity. Novel extraction techniques to obtain plant-derived extracts such as supercritical fluid extraction (SFE), which has gained acceptance for the extraction of valuable substances due to its environmentally friendly character, or ultrasound-assisted extraction (UAE). The extraction techniques of the plant-derived bioactive compounds have a significant impact on the quality of the extracts and their chemical composition

Technology: general issues --- Biotechnology --- lactic acid bacteria --- plant extracts --- milk fermentation --- total phenolic content --- antioxidant capacities --- seed oils --- antibacterial properties --- cytotoxicity --- antifungal properties --- omega-3 fatty acids --- omega-6 fatty acids --- antitumor activities --- Portulaca oleracea L. --- Luffa aegyptica Mill. --- Cucurbita maxima L. --- Linum usitatissimum L. --- aflatoxin B1 --- Aspergillus flavus --- carotenoids --- curcumin --- maize varieties --- photosensitization --- preservation technique --- Actinidia deliciosa --- by-product valorization --- extraction optimization --- bioactive properties --- natural ingredients --- antifungal activity --- biological plant protection --- cereals quality --- essential oils --- ergosterol --- food chain safety --- Fusarium spp. --- mycotoxins --- antioxidant activity --- antimicrobial properties --- biofilm --- Glechoma hederacea --- supercritical fluid extraction --- n/a

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Microbial contamination of agriculture and food commodities may cause significant losses, with economic, social and environmental consequences. Therefore, the search for new, promising substances that demonstrate antagonism towards different microorganisms has been observed in recent years. Different plants, as well as differentiated methods of obtaining of biological compounds, are the research subject. Moreover, current trends focus on the sustainable recovery of antimicrobial substances from waste materials. The contributed articles present original research with a focus on: The biological activity of plant-derived extracts and oils: the research is concentrated on the discovery of new sufficient antimicrobial substances, characterized by broad biological properties including antibacterial, antifungal, antimycotoxigenic and cytotoxic activity. Novel extraction techniques to obtain plant-derived extracts such as supercritical fluid extraction (SFE), which has gained acceptance for the extraction of valuable substances due to its environmentally friendly character, or ultrasound-assisted extraction (UAE). The extraction techniques of the plant-derived bioactive compounds have a significant impact on the quality of the extracts and their chemical composition

lactic acid bacteria --- plant extracts --- milk fermentation --- total phenolic content --- antioxidant capacities --- seed oils --- antibacterial properties --- cytotoxicity --- antifungal properties --- omega-3 fatty acids --- omega-6 fatty acids --- antitumor activities --- Portulaca oleracea L. --- Luffa aegyptica Mill. --- Cucurbita maxima L. --- Linum usitatissimum L. --- aflatoxin B1 --- Aspergillus flavus --- carotenoids --- curcumin --- maize varieties --- photosensitization --- preservation technique --- Actinidia deliciosa --- by-product valorization --- extraction optimization --- bioactive properties --- natural ingredients --- antifungal activity --- biological plant protection --- cereals quality --- essential oils --- ergosterol --- food chain safety --- Fusarium spp. --- mycotoxins --- antioxidant activity --- antimicrobial properties --- biofilm --- Glechoma hederacea --- supercritical fluid extraction --- n/a

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A compilation of 12 original research articles and a review on the development of instrumental and immunoanalytical methods for mycotoxins; on the enhancement of sample preparation and selection to improve method applicability; and on practical applications of analytical methods in laboratory fungal cultures, cereal and feed samples, surface water (as a novel matrix of mycotoxins as emerging surface water contaminants), and during mycotoxin decontamination by bacteria. Target analyte mycotoxins include aflatoxins, deoxynivalenol, diacetoxyscirpenol, fumonisins, fusarenone-X, HT-2 toxins, nivalenol, ochratoxins, sterigmatocystin, T-2 toxin, and zearalenone.

Research & information: general --- aflatoxins --- laboratory culture --- extraction --- HPLC --- recovery --- detection limits --- frequency mixing technology --- immunofiltration --- magnetic beads --- mycotoxin --- type B trichothecenes --- modified mycotoxins --- isomer separation --- method validation --- ochratoxin A --- fluorescence --- G-quadruplex --- biosensor --- computation --- simulation --- mycotoxins --- feed --- modified QuEChERS --- LC-MS/MS --- zearalenone --- immunochromatographic assay --- semi-quantification --- quantification --- aflatoxin B1 --- sterigmatocystin --- lactobacilli --- mycotoxin binding --- detoxification --- lactic acid bacteria --- colorimetric detection --- rapid tests --- ELISA --- lateral flow assays --- microfluidics --- nano-materials --- food safety --- commercialization --- immunosensor --- optical waveguide lightmode spectroscopy --- label-free detection --- planar waveguide sensor --- polarisation interferometer --- limit of detection --- competitive immunoassay --- fluorescence detection --- high-performance liquid chromatography --- total internal reflection ellipsometry --- aflatoxin --- chicken feed --- representative sampling --- improved aflatoxin test procedure --- validation --- aflatoxins --- laboratory culture --- extraction --- HPLC --- recovery --- detection limits --- frequency mixing technology --- immunofiltration --- magnetic beads --- mycotoxin --- type B trichothecenes --- modified mycotoxins --- isomer separation --- method validation --- ochratoxin A --- fluorescence --- G-quadruplex --- biosensor --- computation --- simulation --- mycotoxins --- feed --- modified QuEChERS --- LC-MS/MS --- zearalenone --- immunochromatographic assay --- semi-quantification --- quantification --- aflatoxin B1 --- sterigmatocystin --- lactobacilli --- mycotoxin binding --- detoxification --- lactic acid bacteria --- colorimetric detection --- rapid tests --- ELISA --- lateral flow assays --- microfluidics --- nano-materials --- food safety --- commercialization --- immunosensor --- optical waveguide lightmode spectroscopy --- label-free detection --- planar waveguide sensor --- polarisation interferometer --- limit of detection --- competitive immunoassay --- fluorescence detection --- high-performance liquid chromatography --- total internal reflection ellipsometry --- aflatoxin --- chicken feed --- representative sampling --- improved aflatoxin test procedure --- validation