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Pharmacology. Therapy --- Allergy --- Pathological biochemistry --- Pathology of the respiratory system --- Asthma --- Beta adrenoceptors --- Receptors, Adrenergic, beta --- Receptor, Adrenergic, beta --- Adrenergic beta-Receptor --- Adrenergic beta-Receptors --- Receptors, beta-Adrenergic --- beta Adrenergic Receptor --- beta-Adrenergic Receptor --- beta-Adrenergic Receptors --- Adrenergic Receptor, beta --- Adrenergic beta Receptor --- Adrenergic beta Receptors --- Receptor, beta Adrenergic --- Receptor, beta-Adrenergic --- Receptors, beta Adrenergic --- beta Adrenergic Receptors --- beta-Receptor, Adrenergic --- beta-Receptors, Adrenergic --- Asthma, Bronchial --- Bronchial Asthma --- Asthmas --- Bronchial Hyperreactivity --- Adrenergic beta receptors --- Adrenergic receptors, Beta --- Adrenoceptors, Beta --- Beta adrenergic receptors --- Receptors, Beta adrenergic --- Adrenaline --- Adrenergic beta agonists --- Adrenergic beta blockers --- Bronchial asthma --- Bronchi --- Lungs --- Respiratory allergy --- Molecular aspects&delete& --- Congresses --- Receptors --- Diseases --- Diseases, Obstructive --- Conferences - Meetings --- Molecular aspects
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The Beta-3 Adrenoreceptor plays an important role in regulating human fat storage and variants of this receptor are thought to be relevant to diabetes.In addition to the major interest in obesity and diabetes expressed by the pharmaceutical industry, increasing numbers of academic groups are attracted by this general research area. This renewed interest is of course in part stimulated by available financing from industry. It also reflects the growing realisation that metabolism remains an open frontier: little is known about adipocyte sub-populations, specific markers, or endocrine functio
Beta adrenoceptors. --- Adrenergic beta agonists. --- Adrenergic beta receptor agonists --- Beta adrenergic agonists --- Beta adrenergic receptor agonists --- Beta adrenoceptor agonists --- Beta agonists --- Beta sympathomimetic agents --- Beta sympathomimetics --- Sympathomimetic agents --- Beta adrenoceptors --- Adrenergic beta receptors --- Adrenergic receptors, Beta --- Adrenoceptors, Beta --- Beta adrenergic receptors --- Receptors, Beta adrenergic --- Adrenaline --- Adrenergic beta agonists --- Adrenergic beta blockers --- Receptors
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Catecholamines --- Adrenaline --- Physiological effect --- Receptors --- -Catecholamines --- -#Lilly --- Sympathins --- Amines --- Biogenic amines --- Chromaffin cells --- Hormones --- Adrenalin --- Epinephrine --- Bronchodilator agents --- Neurotransmitters --- Sympathomimetic agents --- Adrenergic mechanisms --- #Lilly --- Adrenergic receptors --- Adrenoceptors --- Adrenoreceptors --- Receptors, Adrenergic --- Sympathetic nervous system --- Catecholamines - Physiological effect --- Adrenaline - Receptors
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Pharmacology. Therapy --- Adrenergic mechanisms --- Adrenergic receptors --- Radioligand assay --- Receptors, Adrenergic --- Binding sites --- Adrenaline --- Radioligand Assay --- BINDING SITES --- RECEPTORS, ADRENERGIC --- Receptors --- Binding Sites. --- Radioligand Assay. --- Receptors, Adrenergic. --- -Adrenergic mechanisms --- #Lilly --- Binding assay, Radioligand --- Competitive protein binding assay --- Ligand binding assay (Biochemistry) --- Protein binding assay --- Radioreceptor assay --- Receptor binding assay --- Tissue receptor assay --- Analytical biochemistry --- Ligand binding (Biochemistry) --- Protein binding --- Sympathetic nervous system --- Adrenalin --- Epinephrine --- Bronchodilator agents --- Catecholamines --- Neurotransmitters --- Sympathomimetic agents --- Adrenergic Receptor --- Epinephrine Receptors --- Norepinephrine Receptors --- Adrenergic Receptors --- Adrenoceptors --- Receptors, Epinephrine --- Receptors, Norepinephrine --- Receptor, Adrenergic --- Norepinephrine --- Sympathomimetics --- Racepinephrine --- Protein-Binding Radioassay --- Radioreceptor Assay --- Assay, Radioligand --- Assay, Radioreceptor --- Assays, Radioligand --- Assays, Radioreceptor --- Protein Binding Radioassay --- Protein-Binding Radioassays --- Radioassay, Protein-Binding --- Radioassays, Protein-Binding --- Radioligand Assays --- Radioreceptor Assays --- Ligands --- Protein Binding --- Binding Site --- Combining Site --- Combining Sites --- Site, Binding --- Site, Combining --- Sites, Binding --- Sites, Combining --- Protein Interaction Mapping --- Receptors. --- Binding Sites --- Adrenoreceptors --- Adrenoceptor --- Norepinephrine Receptor --- Receptor, Norepinephrine --- Adrenaline - Receptors
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The adrenergic receptors control many critical functions of the heart, kidney, brain, and all organs under autonomic control. Today significant opportunities exist for molecular and genetic analysis of their function and signaling pathways. In The Adrenergic Receptors: In the 21st Century, senior scientists who have developed novel molecular approaches describe the state-of-the-art understanding of the structure and function of the adrenergic receptor subtypes, as well as the role played by these receptors in physiological and pathophysiological settings. Topics range from structure-function studies and the imaging of adrenergic receptors to the use of genetically altered mouse models and pharmacogenomics. Many of the methods described can be applied to characterize any receptor of interest. Highlights include a survey of the knockout and overexpressed mouse models, a review of the new ways that adrenergic receptors can signal, and the effects of polymorphisms on both clinical outcomes and potential gene therapy applications. Additional chapters address modern techniques for assessing adrenergic function, such as fluorescent labeling and microarrays, and offer an insightful historical survey of the extraordinary progress made in our understanding of these receptors in the twentieth century. Comprehensive and authoritative, The Adrenergic Receptors: In the 21st Century provides researchers-through its side-by-side comparison of all the adrenergic receptors (a1, a2, and b) and their subtypes-with an excellent survey of the field, including the rationale for how best to design better drugs for control of the heart, blood pressure, and related pathophysiological systems.
Adrenaline -- Receptors. --- Pharmacogenetics. --- Adrenaline --- Pharmacogenetics --- Pharmacology --- Receptors, Catecholamine --- Genetics --- Health Occupations --- Biological Science Disciplines --- Biology --- Receptors, G-Protein-Coupled --- Receptors, Biogenic Amine --- Natural Science Disciplines --- Receptors, Cell Surface --- Receptors, Neurotransmitter --- Disciplines and Occupations --- Membrane Proteins --- Proteins --- Amino Acids, Peptides, and Proteins --- Chemicals and Drugs --- Receptors, Adrenergic --- Health & Biological Sciences --- Human Anatomy & Physiology --- Neuroscience --- Pharmacy, Therapeutics, & Pharmacology --- Receptors --- Receptors. --- Adrenergic receptors --- Adrenoceptors --- Adrenoreceptors --- Genetic aspects --- Pharmacy. --- Chemistry --- Medicine --- Drugs --- Materia medica --- Biochemical genetics --- Sympathetic nervous system
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Gynaecology. Obstetrics --- Biopharmaco-efficiency. Pharmacokinetics --- Pregnancy. --- Drug Therapy. --- Fetus --- Infant, Newborn. --- Perinatology. --- Receptors, Adrenergic. --- Receptors, Adrenergic, beta. --- Receptor, Adrenergic, beta --- Adrenergic beta-Receptors --- Receptors, beta-Adrenergic --- beta-Adrenergic Receptors --- Adrenergic beta Receptors --- Receptors, beta Adrenergic --- beta Adrenergic Receptors --- beta-Receptors, Adrenergic --- Adrenergic Receptor --- Epinephrine Receptors --- Norepinephrine Receptors --- Adrenergic Receptors --- Adrenoceptors --- Receptors, Epinephrine --- Receptors, Norepinephrine --- Receptor, Adrenergic --- Epinephrine --- Norepinephrine --- Sympathomimetics --- Racepinephrine --- Newborns --- Neonate --- Infants, Newborn --- Neonates --- Newborn --- Newborn Infant --- Newborn Infants --- Neonatology --- Therapy, Drug --- Chemotherapy --- Pharmacotherapy --- Chemotherapies --- Drug Therapies --- Pharmacotherapies --- Therapies, Drug --- Disease --- Pharmaceutical Preparations --- Pharmacologic Actions --- Gestation --- Pregnancies --- Litter Size --- Maternal-Fetal Relations --- Pregnant Women --- drug effects. --- drug therapy --- therapeutic use --- Adrenergic beta-Receptor --- beta Adrenergic Receptor --- beta-Adrenergic Receptor --- Adrenergic Receptor, beta --- Adrenergic beta Receptor --- Receptor, beta Adrenergic --- Receptor, beta-Adrenergic --- beta-Receptor, Adrenergic --- Adrenoceptor --- Norepinephrine Receptor --- Receptor, Norepinephrine --- Fetal Medicine --- Maternal-Fetal Medicine --- Materno-Fetal Medicine --- Fetal Medicines --- Maternal Fetal Medicine --- Maternal-Fetal Medicines --- Materno Fetal Medicine --- Materno-Fetal Medicines --- Medicine, Fetal --- Medicine, Maternal-Fetal --- Medicine, Materno-Fetal --- Pregnancy --- Drug Therapy --- Infant, Newborn --- Perinatology --- Receptors, Adrenergic --- Receptors, Adrenergic, beta --- drug effects
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Receptors, Adrenergic --- Drug effects --- Congresses. --- Physiology --- Receptors, Adrenergic. --- 615.21 --- Adrenergic Receptor --- Epinephrine Receptors --- Norepinephrine Receptors --- Adrenergic Receptors --- Adrenoceptors --- Receptors, Epinephrine --- Receptors, Norepinephrine --- Receptor, Adrenergic --- Epinephrine --- Norepinephrine --- Sympathomimetics --- Racepinephrine --- drug effects. --- physiology. --- Agents predominantly affecting the nervous system --- Adrenaline --- Adrenergic mechanisms --- Neuropharmacology --- Sympathomimetic agents --- Pharmacology --- Receptors --- Effect of drugs on --- Textbooks & monographs 1891-2000 --- Textbooks & monographs 1891-2000. --- 615.21 Agents predominantly affecting the nervous system --- Adrenergic activators --- Adrenergic agents --- Adrenomimetics --- Sympathetic transmitter releasers --- Autonomic drugs --- Biomimetics --- Sympathetic nervous system --- Adrenalin --- Bronchodilator agents --- Catecholamines --- Neurotransmitters --- Receptors&delete& --- Congresses --- Effect of drugs on&delete& --- drug effects --- physiology --- Adrenoceptor --- Norepinephrine Receptor --- Receptor, Norepinephrine
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"The Global Impact of Ergot Alkaloids" addresses the very broad topic of ergot alkaloids and the influence that they have on many facets of life. The content in this Special Issue pertains to research studying fungi, plants, livestock, and humans. While the perspectives of each paper may differ, the common aspect is the interest and emphasis on ergot alkaloids. These compounds cross the spectrum from feared toxins to potential pharmaceutical discoveries. The research included spans the globe and has content that will attract the interest of readers from many different backgrounds.
Medicine --- Medical toxicology --- ergot alkaloids --- strain improvement --- UV --- EMS --- Penicillium citrinum --- response surface methodology --- PBD --- BBD --- integrative interactomics --- integrome --- metabolomics --- microbiome --- tall fescue --- Epichloë coenophiala --- fescue toxicosis --- ergot alkaloid occurrence --- sclerotia --- cereals --- LC-MS/MS --- correlation --- survey --- beef cattle --- endophyte --- ergot alkaloid --- isoflavone --- metabolites --- genetic tolerance --- cytokines --- cow productivity --- CRISPR/Cas9 --- non-transgenic engineered fungi --- genome editing --- genome sequencing --- MinION --- nanopore --- secondary metabolites --- endophyte transmission --- livestock safety --- insect testing --- quality control --- alkaloid profile --- single nucleotide polymorphism --- milk production --- calf growth --- acute ergot exposure --- ergot toxicity --- sheep --- vasoconstriction --- adrenergic receptors --- ergot --- ethnopharmacology --- abortion --- childbirth --- ergovaline --- horse pastures --- pregnant mares --- species composition --- ergot fungi --- gene divergence --- gene diversity --- indole diterpenes --- phylogeny --- Claviceps purpurea --- fungal plant pathogen --- biosynthetic gene cluster --- mycotoxins --- untargeted metabolomics --- mass spectrometry --- blood vessel --- myograph --- serotonin --- ergot alkaloids --- strain improvement --- UV --- EMS --- Penicillium citrinum --- response surface methodology --- PBD --- BBD --- integrative interactomics --- integrome --- metabolomics --- microbiome --- tall fescue --- Epichloë coenophiala --- fescue toxicosis --- ergot alkaloid occurrence --- sclerotia --- cereals --- LC-MS/MS --- correlation --- survey --- beef cattle --- endophyte --- ergot alkaloid --- isoflavone --- metabolites --- genetic tolerance --- cytokines --- cow productivity --- CRISPR/Cas9 --- non-transgenic engineered fungi --- genome editing --- genome sequencing --- MinION --- nanopore --- secondary metabolites --- endophyte transmission --- livestock safety --- insect testing --- quality control --- alkaloid profile --- single nucleotide polymorphism --- milk production --- calf growth --- acute ergot exposure --- ergot toxicity --- sheep --- vasoconstriction --- adrenergic receptors --- ergot --- ethnopharmacology --- abortion --- childbirth --- ergovaline --- horse pastures --- pregnant mares --- species composition --- ergot fungi --- gene divergence --- gene diversity --- indole diterpenes --- phylogeny --- Claviceps purpurea --- fungal plant pathogen --- biosynthetic gene cluster --- mycotoxins --- untargeted metabolomics --- mass spectrometry --- blood vessel --- myograph --- serotonin
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"The Global Impact of Ergot Alkaloids" addresses the very broad topic of ergot alkaloids and the influence that they have on many facets of life. The content in this Special Issue pertains to research studying fungi, plants, livestock, and humans. While the perspectives of each paper may differ, the common aspect is the interest and emphasis on ergot alkaloids. These compounds cross the spectrum from feared toxins to potential pharmaceutical discoveries. The research included spans the globe and has content that will attract the interest of readers from many different backgrounds.
ergot alkaloids --- strain improvement --- UV --- EMS --- Penicillium citrinum --- response surface methodology --- PBD --- BBD --- integrative interactomics --- integrome --- metabolomics --- microbiome --- tall fescue --- Epichloë coenophiala --- fescue toxicosis --- ergot alkaloid occurrence --- sclerotia --- cereals --- LC-MS/MS --- correlation --- survey --- beef cattle --- endophyte --- ergot alkaloid --- isoflavone --- metabolites --- genetic tolerance --- cytokines --- cow productivity --- CRISPR/Cas9 --- non-transgenic engineered fungi --- genome editing --- genome sequencing --- MinION --- nanopore --- secondary metabolites --- endophyte transmission --- livestock safety --- insect testing --- quality control --- alkaloid profile --- single nucleotide polymorphism --- milk production --- calf growth --- acute ergot exposure --- ergot toxicity --- sheep --- vasoconstriction --- adrenergic receptors --- ergot --- ethnopharmacology --- abortion --- childbirth --- ergovaline --- horse pastures --- pregnant mares --- species composition --- ergot fungi --- gene divergence --- gene diversity --- indole diterpenes --- phylogeny --- Claviceps purpurea --- fungal plant pathogen --- biosynthetic gene cluster --- mycotoxins --- untargeted metabolomics --- mass spectrometry --- blood vessel --- myograph --- serotonin --- n/a --- Epichloë coenophiala
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